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Author Details

Thierry Lepage
Institut Biology Valrose, Universite Cote d'Azur
1974
64
30
PMIDPaper TitleJournal TitlePublished Year
37407549RAS-independent ERK activation by constitutively active KSR3 in non-chordate metazoa.Nat Commun2023
37082140Analysis of the <i>P. lividus</i> sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes.Cell Genom2023
33298464Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo.Development2021
32591077Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo.Curr Top Dev Biol2020
30948011Expression of exogenous mRNAs to study gene function in echinoderm embryos.Methods Cell Biol2019
31479176A wnt2 ortholog in the sea urchin Paracentrotus lividus.Genesis2019
30222786MAPK and GSK3/ÿ-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo.PLoS Genet2018
28507001p38 MAPK as an essential regulator of dorsal-ventral axis specification and skeletogenesis during sea urchin development: a re-evaluation.Development2017
26778142A minimal molecular toolkit for mineral deposition? Biochemistry and proteomics of the test matrix of adult specimens of the sea urchin Paracentrotus lividus.J Proteomics2016
26582589A deuterostome origin of the Spemann organiser suggested by Nodal and ADMPs functions in Echinoderms.Nat Commun2015
26352141The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo.PLoS Biol2015
26423516A deuterostome origin of the Spemann organiser suggested by Nodal and ADMPs functions in Echinoderms.Nat Commun2015
23769944Nodal: master and commander of the dorsal-ventral and left-right axes in the sea urchin embryo.Curr Opin Genet Dev2013
23271979Reciprocal signaling between the ectoderm and a mesendodermal left-right organizer directs left-right determination in the sea urchin embryo.PLoS Genet2012
21750039Wnt6 activates endoderm in the sea urchin gene regulatory network.Development2011
21782809Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo.Dev Biol2011
20040489Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo.Development2010
21203442Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm.PLoS Genet2010
19956794Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network.PLoS Biol2009
16838294A conserved role for the nodal signaling pathway in the establishment of dorso-ventral and left-right axes in deuterostomes.J Exp Zool B Mol Dev Evol2008
18582858Lefty acts as an essential modulator of Nodal activity during sea urchin oral-aboral axis formation.Dev Biol2008
18077587FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis [corrected] and regulate gastrulation during sea urchin development.Development2008
17855430Cis-regulatory analysis of nodal and maternal control of dorsal-ventral axis formation by Univin, a TGF-beta related to Vg1.Development2007
16672336Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling.Development2006
17038519Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo.Development2006
17095691The genome of the sea urchin Strongylocentrotus purpuratus.Science2006
17061352Expression pattern of three putative RNA-binding proteins during early development of the sea urchin Paracentrotus lividus.Gene Expr Patterns2006
17027740The sea urchin kinome: a first look.Dev Biol2006
17084834RTK and TGF-beta signaling pathways genes in the sea urchin genome.Dev Biol2006
15992548Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side.Dev Cell2005
15030762Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo.Dev Cell2004
15575626Expression of exogenous mRNAs to study gene function in the sea urchin embryo.Methods Cell Biol2004
14973284A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets.Development2004
12844016[Factors predicting the severity and the degree of symptom control of asthma in a recently diagnosed cohort of adult patients (A.S.M.A study)].Rev Mal Respir2003
11995381[Development over 3 years of asthma recently diagnosed in a cohort of children (ASMA study). Factors related to improvement in clinical status].Presse Med2002
12397099Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish.Development2002
11829094Guidelines versus clinical practice in the treatment of chronic obstructive pulmonary disease.Eur Respir J2001
11203696The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. .Dev Biol2001
10921462Asthma in adults: comparison of adult-onset asthma with childhood-onset asthma relapsing in adulthood.Allergy2000
10433906nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate.Development1999
9609832GSK3beta/shaggy mediates patterning along the animal-vegetal axis of the sea urchin embryo.Development1998
9411613[Asthma in private pneumology practice].Rev Mal Respir1997
8706676Structure of the gene encoding the sea urchin blastula protease 10 (BP10), a member of the astacin family of Zn2+-metalloproteases.Eur J Biochem1996
7854456Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning.Nature1995
8112336Structure of the sea urchin hatching enzyme gene.Eur J Biochem1994
7679074Cell-autonomous expression and position-dependent repression by Li+ of two zygotic genes during sea urchin early development.EMBO J1993
1302080[Color doppler echography in the exploration of vasculogenic impotence].Prog Urol1992
1537434Spatial expression of the hatching enzyme gene in the sea urchin embryo.Dev Biol1992
1339338Spatial and temporal expression pattern during sea urchin embryogenesis of a gene coding for a protease homologous to the human protein BMP-1 and to the product of the Drosophila dorsal-ventral patterning gene tolloid.Development1992
2167841Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo.EMBO J1990
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Collaborators

Sorbonne Universite, CNRS
Co-authored papers 15
Universite Cote d'Azur, CNRS, Inserm
Co-authored papers 12
Universite Cote d'Azur-CNRS-Inserm-Institute for Research on Cancer and Ageing
Co-authored papers 10
Department of Medical Genetics of Nice Universitary Hospital
Co-authored papers 10
Auburn University
Co-authored papers 7
Sorbonne Universite, CNRS
Co-authored papers 5
Duke University
Co-authored papers 5
Boston University
Co-authored papers 3
CTO Hospital
Co-authored papers 3
California State University
Co-authored papers 3
Istituto per la Ricerca e l'Innovazione Biomedica (IRIB)
Co-authored papers 3
Institute of Aerospace and Undersea Medicine, National Defense Medical Center
Co-authored papers 3
CNRS, Sorbonne Universite
Co-authored papers 3
Max-Planck-Institut fur Molekulare Genetik
Co-authored papers 3
Universitat de Barcelona
Co-authored papers 2
Western Michigan University
Co-authored papers 2
Present address: King Abdullah University of Science and Technology
Co-authored papers 2
CNR-Istituto per la Protezione Sostenibile delle Piante
Co-authored papers 2
Duke University
Co-authored papers 2
National Institute of Dental and Craniofacial Research, National Institutes of Health
Co-authored papers 2
St. Petersburg College
Co-authored papers 2
Saitama University
Co-authored papers 2
University of Delhi South Campus
Co-authored papers 2
University of Gothenburg
Co-authored papers 2
Duke University Medical Center
Co-authored papers 2
University of Maine
Co-authored papers 2
Complex Systems Institute Paris Ile-de-France (ISC-PIF, CNRS
Co-authored papers 2
Cellular and Developmental Biology and Marine Science Institute
Co-authored papers 2
University of New Orleans
Co-authored papers 2
National Science Foundation
Co-authored papers 2