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Author Details

David W Fardo
University of Kentucky
2007
138
39
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37592813Different cohort, disparate results: Selection bias is a key factor in autopsy cohorts.Alzheimers Dement2024
36840666Associations of potential ADRD plasma biomarkers in cognitively normal volunteers.Alzheimers Dement2023
37528055LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry.J Neuropathol Exp Neurol2023
37658433Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.J Neuroinflammation2023
37641147A neuropathologic feature of brain aging: multi-lumen vascular profiles.Acta Neuropathol Commun2023
37248909Urinary Incontinence in a Community-Based Autopsy Cohort Is Associated with Limbic Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Changes.J Alzheimers Dis2023
37269007Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort.Acta Neuropathol Commun2023
37461624Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies <i>LRRC4C, LHX5-AS1</i> and nominates ancestry-specific loci <i>PTPRK</i> , <i>GRB14</i> , and <i>KIAA0825</i> as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.medRxiv2023
35023380Apolipoprotein E ε4/4 genotype limits response to dietary induction of hyperhomocysteinemia and resulting inflammatory signaling.J Cereb Blood Flow Metab2022
35379992New insights into the genetic etiology of Alzheimer's disease and related dementias.Nat Genet2022
35552371Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.Brain2022
36514441Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue.Alzheimers Dement (N Y)2022
36506564The association of gabapentin initiation and neurocognitive changes in older adults with normal cognition.Front Pharmacol2022
36191742Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.Neurobiol Dis2022
35156446Genome-wide association study of brain arteriolosclerosis.J Cereb Blood Flow Metab2022
35094057Cancer diagnosis is associated with a lower burden of dementia and less Alzheimer's-type neuropathology.Brain2022
35121671Limbic-Predominant Age-Related TDP-43 Encephalopathy: Medical and Pathologic Factors Associated With Comorbid Hippocampal Sclerosis.Neurology2022
33098484Brain arteriolosclerosis.Acta Neuropathol2021
33812378Age and sex are associated with the plasma lipidome: findings from the GOLDN study.Lipids Health Dis2021
33694178Reduced rank multinomial logistic regression in Markov chains with application to cognitive data.Stat Med2021
34526147Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study.Acta Neuropathol Commun2021
34486652Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status.J Neuropathol Exp Neurol2021
34604500Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes.Alzheimers Dement (N Y)2021
34326369Predictors of chronic opioid therapy in Medicaid beneficiaries with HIV who initiated antiretroviral therapy.Sci Rep2021
34214102Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.PLoS One2021
34208838Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer's Disease Risk Reveal a Potential Role for SIGLEC14.Genes (Basel)2021
34057090Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies.J Alzheimers Dis2021
34055880A Highly Predictive MicroRNA Panel for Determining Delayed Cerebral Vasospasm Risk Following Aneurysmal Subarachnoid Hemorrhage.Front Mol Biosci2021
30514930Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.Mol Psychiatry2020
31748784Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene.J Neuropathol Exp Neurol2020
32797255Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy.Acta Neuropathol2020
32844198Genetic variants and functional pathways associated with resilience to Alzheimer's disease.Brain2020
32116527Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflammatory Biomarkers.Front Neurosci2020
32414344Quantitative phenotype scan statistic (QPSS) reveals rare variant associations with Alzheimer's disease endophenotypes.BMC Med Genet2020
32357373The MUC6/AP2A2 Locus and Its Relevance to Alzheimer's Disease: A Review.J Neuropathol Exp Neurol2020
32568358Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults.JAMA Neurol2020
30647434Correction: Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.Mol Psychiatry2020
29653492Visual Arts Education improves self-esteem for persons with dementia and reduces caregiver burden: A randomized controlled trial.Dementia (London)2019
31649416Estimation of Multi-state Models with Missing Covariate Values Based on Observed Data Likelihood.Commun Stat Theory Methods2019
30219892Principals about principal components in statistical genetics.Brief Bioinform2019
30742063Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy.Lab Invest2019
30949760Evaluation of CD33 as a genetic risk factor for Alzheimer's disease.Acta Neuropathol2019
30856115Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis.J Alzheimers Dis2019
30907138Socioemotional selectivity and psychological health in amyotrophic lateral sclerosis patients and caregivers: a longitudinal, dyadic analysis.Psychol Health2019
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
30633773Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study.PLoS One2019
30377206Characterization of Squamous Cell Lung Cancers from Appalachian Kentucky.Cancer Epidemiol Biomarkers Prev2019
30682540TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.Neurobiol Dis2019
30448613Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.Neurobiol Aging2019
29186501The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases.J Neuropathol Exp Neurol2018
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Collaborators

University of Kentucky
Co-authored papers 31
University of Kentucky
Co-authored papers 30
University of Kentucky
Co-authored papers 19
Rush University Medical Center
Co-authored papers 14
University of Washington
Co-authored papers 12
Brigham Young University
Co-authored papers 11
Indiana University School of Medicine
Co-authored papers 10
University of Washington
Co-authored papers 9
Cleveland Institute for Computational Biology, Case Western Reserve University
Co-authored papers 9
University of Kentucky
Co-authored papers 9
Washington University School of Medicine
Co-authored papers 9
Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 9
Co-authored papers 8
University of Washington
Co-authored papers 8
Co-authored papers 7
Co-authored papers 7
Rush University Medical Center
Co-authored papers 7
Stanford University
Co-authored papers 6
Co-authored papers 6
University of Washington
Co-authored papers 6
University of Pittsburgh
Co-authored papers 5
Co-authored papers 5
Mayo Clinic Jacksonville
Co-authored papers 5
University of Pennsylvania
Co-authored papers 5
Brigham Young University
Co-authored papers 5
Columbia University Irving Medical Center, New York Presbyterian Hospital
Co-authored papers 5
University of Washington School of Medicine
Co-authored papers 5
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Mayo Clinic
Co-authored papers 5