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Author Details

Song Tan
Penn State University, University Park
1988
68
37
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36623730Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration.J Biol Chem2023
37546845Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C.Res Sq2023
37058572Cryo-EM structure of the human Sirtuin 6-nucleosome complex.Sci Adv2023
36993468Cryo-EM structure of the human Sirtuin 6-nucleosome complex.bioRxiv2023
36996811Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions.Mol Cell2023
32890768The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module.Biochim Biophys Acta Gene Regul Mech2021
34408191The Penn State Protein Ladder system for inexpensive protein molecular weight markers.Sci Rep2021
34198054Principles of nucleosome recognition by chromatin factors and enzymes.Curr Opin Struct Biol2021
32396821Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.Mol Cell2020
33357431Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.Cell Rep2020
30224453Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.Proc Natl Acad Sci U S A2018
28550309The pPSU Plasmids for Generating DNA Molecular Weight Markers.Sci Rep2017
26953260Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.J Mol Biol2016
27219518Differentially Isotope-Labeled Nucleosomes To Study Asymmetric Histone Modification Crosstalk by Time-Resolved NMR Spectroscopy.Angew Chem Int Ed Engl2016
27372748Preparation, Crystallization, and Structure Determination of Chromatin Enzyme/Nucleosome Complexes.Methods Enzymol2016
26739786Elimination of truncated recombinant protein expressed in Escherichia coli by removing cryptic translation initiation site.Protein Expr Purif2016
26764865Recognition of the nucleosome by chromatin factors and enzymes.Curr Opin Struct Biol2016
25495456Nucleosome structure and function.Chem Rev2015
26420880Site specificity analysis of Piccolo NuA4-mediated acetylation for different histone complexes.Biochem J2015
25916846Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex.Nucleic Acids Res2015
25355358Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.Nature2014
23109429Piccolo NuA4-catalyzed acetylation of nucleosomal histones: critical roles of an Esa1 Tudor/chromo barrel loop and an Epl1 enhancer of polycomb A (EPcA) basic region.Mol Cell Biol2013
24065767Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.Genes Dev2013
23928047Strategies for crystallizing a chromatin protein in complex with the nucleosome core particle.Anal Biochem2013
23453805ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes.Mol Cell2013
23352377Protein-nucleic interactions: 'I have a cunning plan⿦'.Curr Opin Struct Biol2013
22435811Deciphering how the chromatin factor RCC1 recognizes the nucleosome: the importance of individuals in the scientific discovery process.Biochem Soc Trans2012
21227680Diversity makes for a rich tapestry.Curr Opin Struct Biol2011
21893203Reprint of: Comparison of affinity tags for protein purification.Protein Expr Purif2011
21984211Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes.Nat Struct Mol Biol2011
21673141Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.Proc Natl Acad Sci U S A2011
21749977Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms.Nucleic Acids Res2011
21176878Nucleosome structural studies.Curr Opin Struct Biol2011
20095602DNA methylation increases nucleosome compaction and rigidity.J Am Chem Soc2010
20739938Structure of RCC1 chromatin factor bound to the nucleosome core particle.Nature2010
20347844RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex.J Mol Biol2010
19056063Preface to special issue on epigenetics.Biochim Biophys Acta2009
19822661Set2-dependent K36 methylation is regulated by novel intratail interactions within H3.Mol Cell Biol2009
18491300Recombinant protein complex expression in E. coli.Curr Protoc Protein Sci2008
17223684Catalytic mechanism of a MYST family histone acetyltransferase.Biochemistry2007
18158898Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin.Mol Cell2007
17309836Expression and purification of recombinant yeast Ada2/Ada3/Gcn5 and Piccolo NuA4 histone acetyltransferase complexes.Methods2007
17274630Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex.Biochemistry2007
16387653ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.Mol Cell2006
16888622SAGA binds TBP via its Spt8 subunit in competition with DNA: implications for TBP recruitment.EMBO J2006
15802226Comparison of affinity tags for protein purification.Protein Expr Purif2005
15917248Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1.J Biol Chem2005
15964809The Saccharomyces cerevisiae Piccolo NuA4 histone acetyltransferase complex requires the Enhancer of Polycomb A domain and chromodomain to acetylate nucleosomes.Mol Cell Biol2005
15766881The pST44 polycistronic expression system for producing protein complexes in Escherichia coli.Protein Expr Purif2005
14966270Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.Mol Cell Biol2004
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Collaborators

Centre Hospitalier Universitaire (CHU) de Quebec-Universite Laval Research Center
Co-authored papers 8
Co-authored papers 4
Laval University Cancer Research Center
Co-authored papers 3
Institut NeuroMyoGene, Universite Lyon1-CNRS UMR1-INSERM U1315
Co-authored papers 2
Chittaranjan National Cancer Institute
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park
Co-authored papers 2
Institute of Molecular and Cell Biology, University of Tartu
Co-authored papers 1
The Francis Crick Institute
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of California davis
Co-authored papers 1
1 Global Smile Foundation
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Co-authored papers 1
Ottawa Institute of Systems Biology, University of Ottawa
Co-authored papers 1
Co-authored papers 1
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Northwestern University
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Loyola University Chicago
Co-authored papers 1
University of Laval
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Princeton University
Co-authored papers 1
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Purdue University
Co-authored papers 1
The University of Michigan Medical School ann arbor
Co-authored papers 1
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1