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Author Details

Richard J Gilbertson
Cancer Research UK Cambridge Institute, University of Cambridge
1992
172
77
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37648039SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma.Biochim Biophys Acta Mol Basis Dis2024
37748809KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.Life Sci Alliance2023
37488363Cancers make their own luck: theories of cancer origins.Nat Rev Cancer2023
36175792The NALCN channel regulates metastasis and nonmalignant cell dissemination.Nat Genet2022
35798383Primary cilia control translation and the cell cycle in medulloblastoma.Genes Dev2022
35717535Challenges and opportunities for physician-scientists in advancing cancer research.Trends Cancer2022
36450980Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.Nature2022
33472850Harnessing brain development to understand brain tumours.Development2021
33879448Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.Cancer Discov2021
33741710ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.Cancer Discov2021
33741711<i>ZFTA</i> Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.Cancer Discov2021
33589423Maturation Block in Childhood Cancer.Cancer Discov2021
34613815Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.Sci Transl Med2021
34419838Mechanically matching the rheological properties of brain tissue for drug-delivery in human glioblastoma models.Biomaterials2021
34678152Serial assessment of measurable residual disease in medulloblastoma liquid biopsies.Cancer Cell2021
33405951Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).J Clin Oncol2021
32502305cIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors.Brain Pathol2020
33049203Advances and Challenges in Pediatric and Childhood Cancers.Cancer Cell2020
32675324Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.Genes Dev2020
32553121DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.Dev Cell2020
30366006Preclinical Modeling of Image-Guided Craniospinal Irradiation for Very-High-Risk Medulloblastoma.Int J Radiat Oncol Biol Phys2019
31639040Correction to: DNA methylation signature is prognostic of choroid plexus tumor aggressiveness.Clin Epigenetics2019
31409384DNA methylation signature is prognostic of choroid plexus tumor aggressiveness.Clin Epigenetics2019
31150022Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'.Nat Rev Clin Oncol2019
30733593Challenges to curing primary brain tumours.Nat Rev Clin Oncol2019
30885981Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.Cancer Res2019
30901264Cancer Treatment in the Genomic Era.Annu Rev Biochem2019
29301833Establishing a Preclinical Multidisciplinary Board for Brain Tumors.Clin Cancer Res2018
29999454A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo.Autophagy2018
30205039Multiomic Medulloblastomas.Cancer Cell2018
29949764A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.Cell Rep2018
29753700Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.Lancet Oncol2018
29778738Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial.Lancet Oncol2018
27858204The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.Acta Neuropathol2017
29103956mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.Dev Cell2017
29029386Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors.Oncotarget2017
28504719Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.Oncogene2017
28640709Brain Tumors: Challenges and Opportunities to Cure.J Clin Oncol2017
27050100Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.Cancer Cell2016
26518542Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors.J Neurooncol2016
27565343Multi-organ Mapping of Cancer Risk.Cell2016
27180681Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation.Sci Rep2016
26802130Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study.Drug Metab Dispos2016
27104090Translational Pharmacokinetic-Pharmacodynamic Modeling and Simulation: Optimizing 5-Fluorouracil Dosing in Children With Pediatric Ependymoma.CPT Pharmacometrics Syst Pharmacol2016
27110286Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.Ecancermedicalscience2016
24747973Orthotopic models of pediatric brain tumors in zebrafish.Oncogene2015
26541630Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma.Neuro Oncol2015
26075792An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.Nat Genet2015
26095253Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.Cell2015
26169613Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.J Clin Oncol2015
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Collaborators

David W Ellison
St. Jude Children's Research Hospital
Co-authored papers 53
Amar Gajjar
St. Jude Children's Research Hospital
Co-authored papers 46
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 22
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 20
Steven C Clifford
Wolfson Childhood Cancer Research Centre, Newcastle University Centre for Cancer
Co-authored papers 18
Martine F Roussel
St. Jude Children's Research Hospital
Co-authored papers 17
Maryam Fouladi
Co-authored papers 17
Giles W Robinson
St. Jude Children's Research Hospital
Co-authored papers 16
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 13
Roger J Packer
Brain Tumor Institute, Children's National Hospital
Co-authored papers 13
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 12
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 12
Stewart Goldman
Co-authored papers 11
Sridharan Gururangan
Co-authored papers 11
Murali Chintagumpala
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 11
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 10
Christopher Calabrese
St. Jude Children's Research Hospital
Co-authored papers 9
Daisuke Kawauchi
University of California-San Diego
Co-authored papers 9
Kristian W Pajtler
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg University
Co-authored papers 9
Jinghui Zhang
Changhai Hospital, Second Military Medical University
Co-authored papers 9
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers 8
Brent A Orr
St. Jude Children's Research Hospital
Co-authored papers 8
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers 8
Stephen C Mack
St Jude Children's Research Hospital
Co-authored papers 8
Eric Bouffet
The Hospital for Sick Children
Co-authored papers 8
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 8
Kenneth Aldape
National Cancer Institute
Co-authored papers 7
Timothy N Phoenix
Co-authored papers 7
Tom Curran
Medical University of South Carolina
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Alberto Broniscer
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Release 1.2