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Author Details
Full Name
Carl H June
Affiliation
University of Pennsylvania Department of Pathology & Laboratory Medicine
ORCID
Career Start Year
1978
Papers
577
H Index
157
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37616575
Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy.
Blood
2024
36253610
Author Correction: Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy.
Nat Med
2023
37651540
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy.
Sci Transl Med
2023
37649085
Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function.
Cancer Immunol Res
2023
37735588
A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer.
Nat Cancer
2023
37776850
Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor TÂ cells.
Immunity
2023
37729825
Beyond youth: Understanding CAR T cell fitness in the context of immunological aging.
Semin Immunol
2023
37495877
CAR T therapy beyond cancer: the evolution of a living drug.
Nature
2023
37602495
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering.
Adv Healthc Mater
2023
37058474
Identifying highly active anti-CCR4 CAR T cells for the treatment of T-cell lymphoma.
Blood Adv
2023
36993359
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.
bioRxiv
2023
37347991
T-cell Therapies Targeting Multiple Cancer Antigens: The Power of Many.
Cancer Immunol Res
2023
37312454
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR TÂ cells.
Mol Ther
2023
37115855
Tumor-Derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors.
Cancer Res
2023
37377890
Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma.
Cancer Res Commun
2023
37171449
CD38 as a pan-hematologic target for chimeric antigen receptor TÂ cells.
Blood Adv
2023
36967127
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future.
Keio J Med
2023
36920923
Combined disruption of T cell inflammatory regulators Regnase-1 and Roquin-1 enhances antitumor activity of engineered human T cells.
Proc Natl Acad Sci U S A
2023
36641624
Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy.
Mol Ther
2023
36630514
Chimeric antigen receptor T cells as adjuvant therapy for unresectable adenocarcinoma.
Sci Adv
2023
36413381
Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy.
Blood Cancer Discov
2023
36351239
Impact of poverty and neighborhood opportunity on outcomes for children treated with CD19-directed CAR T-cell therapy.
Blood
2023
34798542
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy.
Curr Opin Immunol
2022
35676488
Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Nature
2022
35440724
Engineered cellular immunotherapies in cancer and beyond.
Nat Med
2022
35705524
Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome Patients with B-Cell ALL Receiving CAR T19.
Clin Cancer Res
2022
35675405
Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL.
Sci Adv
2022
35536669
A phase I trial of cyclosporine for hospitalized patients with COVID-19.
JCI Insight
2022
35417527
Next-Generation CAR T-cell Therapies.
Cancer Discov
2022
36477542
Author Correction: Decade-long leukaemia remissions with persistence of CD4<sup>+</sup> CAR T cells.
Nature
2022
36513049
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Cancer Cell
2022
36423579
CAR T therapy extends its reach to autoimmune diseases.
Cell
2022
35972732
Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [18F]AlF-FAPI-74.
Clin Cancer Res
2022
36329201
Off-the-shelf CAR T cells to treat cancer.
Cell Res
2022
35896010
CAR T-cell Therapy Meets Clonal Hematopoiesis.
Blood Cancer Discov
2022
36380037
Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Nature
2022
36350990
In vivo gene immunotherapy for cancer.
Sci Transl Med
2022
36026513
Changes in Bone Marrow Tumor and Immune Cells Correlate with Durability of Remissions Following BCMA CAR T Therapy in Myeloma.
Blood Cancer Discov
2022
35288695
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy.
Nat Med
2022
35314826
Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues.
Nat Cancer
2022
35110735
Decade-long leukaemia remissions with persistence of CD4<sup>+</sup> CAR T cells.
Nature
2022
35263570
Human epigenetic and transcriptional TÂ cell differentiation atlas for identifying functional TÂ cell-specific enhancers.
Immunity
2022
34990237
CAR T cells produced in vivo to treat cardiac injury.
Science
2022
34675084
Novel Redirected T-Cell Immunotherapies for Advanced Prostate Cancer.
Clin Cancer Res
2022
34669421
Orthogonal Design of Experiments for Optimization of Lipid Nanoparticles for mRNA Engineering of CAR T Cells.
Nano Lett
2022
34521108
A randomized phase 2 trial of idiotype vaccination and adoptive autologous T-cell transfer in patients with multiple myeloma.
Blood
2022
33437036
Nanomaterials for T-cell cancer immunotherapy.
Nat Nanotechnol
2021
33547459
Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.
Nat Med
2021
33571163
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication.
J Clin Invest
2021
33713436
B-cell maturation antigen chimeric antigen receptor T-cell re-expansion in a patient with myeloma following salvage programmed cell death protein 1 inhibitor-based combination therapy.
Br J Haematol
2021
1 - 50 of 577
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Perelman School of Medicine, University of Pennsylvania
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Co-authored papers
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8
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Michael K Racke
The Ohio State University Wexner Medical Center
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University of Colorado School of Medicine
Co-authored papers
6
Frances T Hakim
National Cancer Institute
Co-authored papers
6
Lawrence H Boise
Winship Cancer Institute, Emory University
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5
Seth M Steinberg
Center for Cancer Research, National Cancer Institute
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Antoni Ribas
University of California Los Angeles (university of california los angeles)
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5
Daniel F Heitjan
Co-authored papers
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Steven Z Pavletic
Center for Cancer Research, National Cancer Institute, National Institutes of Health
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5
Donald M O'Rourke
Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania
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Jessica Perazzelli
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