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Author Details

Jason D Merker
UNC School of Medicine, The University of North Carolina at Chapel Hill
1998
57
27
PMIDPaper TitleJournal TitlePublished Year
35687785Clinical Testing for Tumor Cell-Free DNA: College of American Pathologists Proficiency Programs Reveal Practice Trends.Arch Pathol Lab Med2023
35671151Four-Year Laboratory Performance of the First College of American Pathologists In Silico Next-Generation Sequencing Bioinformatics Proficiency Testing Surveys.Arch Pathol Lab Med2023
35277280Differences in the microbial profiles of early stage endometrial cancers between Black and White women.Gynecol Oncol2022
35809752ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group.Ann Oncol2022
35438717Most Frequently Cited Accreditation Inspection Deficiencies for Clinical Molecular Oncology Testing Laboratories and Opportunities for Improvement.Arch Pathol Lab Med2022
35394429PPA2-associated sudden cardiac death: extending the clinical and allelic spectrum in 20 new families.Genet Med2022
36063163Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
35101336Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
33450747An Overview of Characteristics of Clinical Next-Generation Sequencing-Based Testing for Hematologic Malignancies.Arch Pathol Lab Med2021
34400813PPA2-associated sudden cardiac death: extending the clinical and allelic spectrum in 20 new families.Genet Med2021
34505882Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance.Blood Adv2021
31483999Comparative Performance of High-Risk Human Papillomavirus RNA and DNA In Situ Hybridization on College of American Pathologists Proficiency Tests.Arch Pathol Lab Med2020
31986076Proficiency Testing of Standardized Samples Shows High Interlaboratory Agreement for Clinical Next Generation Sequencing-Based Hematologic Malignancy Assays With Survey Material-Specific Differences in Variant Frequencies.Arch Pathol Lab Med2020
30605766Designing and Implementing NGS Tests for Inherited Disorders: A Practical Framework with Step-by-Step Guidance for Clinical Laboratories.J Mol Diagn2019
31702703High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations.Appl Immunohistochem Mol Morphol2019
30811101Revisiting diagnostic criteria for myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis: Borderline cases without anemia exist.Int J Lab Hematol2019
30865489Next-Generation Sequencing (NGS) Methods Show Superior or Equivalent Performance to Non-NGS Methods on <i>BRAF</i>, <i>EGFR</i>, and <i>KRAS</i> Proficiency Testing Samples.Arch Pathol Lab Med2019
30969158Performance Comparison of Different Analytic Methods in Proficiency Testing for Mutations in the <i>BRAF</i>, <i>EGFR</i>, and <i>KRAS</i> Genes: A Study of the College of American Pathologists Molecular Oncology Committee.Arch Pathol Lab Med2019
30376374Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing-Based Oncology Assays.Arch Pathol Lab Med2019
28640241Long-read genome sequencing identifies causal structural variation in a Mendelian disease.Genet Med2018
30373888Impact of somatic and germline mutations on the outcome of systemic mastocytosis.Blood Adv2018
29504847Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.J Clin Oncol2018
29504834Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.Arch Pathol Lab Med2018
29478781Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder.Am J Hum Genet2018
29242895Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing.JAMA Oncol2018
28744009Efficacy and safety of midostaurin in patients with advanced systemic mastocytosis: 10-year median follow-up of a phase II trial.Leukemia2018
28801508Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in <i>Caenorhabditis elegans</i> and <i>Homo sapiens</i>.G3 (Bethesda)2017
29028368A Window Into Clinical Next-Generation Sequencing-Based Oncology Testing Practices.Arch Pathol Lab Med2017
29025582A novel TRIP11-FLT3 fusion in a patient with a myeloid/lymphoid neoplasm with eosinophilia.Cancer Genet2017
29022581The impact of rare variation on gene expression across tissues.Nature2017
26876592Complete response to gemtuzumab ozogamicin in a patient with refractory mast cell leukemia.Leukemia2016
27388684A Model Study of In Silico Proficiency Testing for Clinical Next-Generation Sequencing.Arch Pathol Lab Med2016
27338637A study of the mutational landscape of pediatric-type follicular lymphoma and pediatric nodal marginal zone lymphoma.Mod Pathol2016
25152313College of American Pathologists' laboratory standards for next-generation sequencing clinical tests.Arch Pathol Lab Med2015
25780004Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry.Am J Clin Pathol2015
25412851Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutations.Mod Pathol2015
24618965Clinical interpretation and implications of whole-genome sequencing.JAMA2014
25257203A Balanced Look at the Implications of Genomic (and Other "Omics") Testing for Disease Diagnosis and Clinical Care.Genes (Basel)2014
23563237STAT3 mutations are frequent in CD30+ T-cell lymphomas and T-cell large granular lymphocytic leukemia.Leukemia2013
23872309Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes.Haematologica2013
23862106Feasibility of using microbeads with holographic barcodes to track DNA specimens in the clinical molecular laboratory.PeerJ2013
23138292Assuring the quality of next-generation sequencing in clinical laboratory practice.Nat Biotechnol2012
23606936Next-generation sequencing in hematologic malignancies: what will be the dividends?Ther Adv Hematol2012
19959796Design and evaluation of a real-time PCR assay for quantification of JAK2 V617F and wild-type JAK2 transcript levels in the clinical laboratory.J Mol Diagn2010
20495067Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements.J Immunol2010
20404132Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.Blood2010
19131546Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system.Blood2009
20161664Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing.Sci Transl Med2009
18515193The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae.DNA Repair (Amst)2008
17494722Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray.J Clin Microbiol2007
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Collaborators

Stanford University School of Medicine
Co-authored papers 14
Walter Reed National Military Medical Center
Co-authored papers 9
Current or past members of the College of American Pathologists
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Stanford Medicine Clinical Genomics Program
Co-authored papers 5
Stanford University
Co-authored papers 5
Stanford Medicine Clinical Genomics Program
Co-authored papers 5
Co-authored papers 5
Stanford University
Co-authored papers 4
Co-authored papers 4
University of Texas MD Anderson Cancer Center
Co-authored papers 4
Toronto General Hospital, University Health Network, University of Toronto
Co-authored papers 4
Partners Healthcare Center for Personalized Genetic Medicine
Co-authored papers 3
Newcastle University
Co-authored papers 3
Newcastle upon Tyne Hospitals NHS Foundation Trust
Co-authored papers 3
Stanford University
Co-authored papers 3
Stanford University School of Medicine
Co-authored papers 3
Centene Center for Health Transformation, Centene Corporation
Co-authored papers 3
University Children's Hospital, Paracelsus Medical University
Co-authored papers 3
Vertex Pharmaceuticals
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
Invitae Corporation
Co-authored papers 3
University of California San Francisco
Co-authored papers 2
Genomic Medicine Institute, Cleveland Clinic Lerner Research Institute
Co-authored papers 2
Washington University
Co-authored papers 2
German Cancer Consortium and German Cancer Research Center
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Indiana University School of Medicine
Co-authored papers 2
German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
Co-authored papers 2