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Author Details

Barak Rotblat
Ben-Gurion University of the Negev
2002
60
29
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37100955Apoptotic cell death in disease-Current understanding of the NCCD 2023.Cell Death Differ2023
37805501Ecological network analysis reveals cancer-dependent chaperone-client interaction structure and robustness.Nat Commun2023
37508418Gene Expression and Drug Sensitivity Analysis of Mitochondrial Chaperones Reveals That HSPD1 and TRAP1 Expression Correlates with Sensitivity to Inhibitors of DNA Replication and Mitosis.Biology (Basel)2023
37221009The Fitness Effects of Codon Composition of the Horizontally Transferred Antibiotic Resistance Genes Intensify at Sub-lethal Antibiotic Levels.Mol Biol Evol2023
35228525Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation.Cell Death Discov2022
35379801EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma.Cell Death Discov2022
35831316The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.Nat Commun2022
35292516MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer.J Immunother Cancer2022
34115613<i>TP73-AS1</i> is induced by YY1 during TMZ treatment and highly expressed in the aging brain.Aging (Albany NY)2021
34702855CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice.Nat Commun2021
34039605BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.Sci Adv2021
34067117IGF2 Mediates Resistance to Isoform-Selective-Inhibitors of the PI3K in HPV Positive Head and Neck Cancer.Cancers (Basel)2021
32235444Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning.Cancers (Basel)2020
32033217The Amuvatinib Derivative, N-(2H-1,3-Benzodioxol-5-yl)-4-{thieno[3,2-d]pyrimidin-4-yl}piperazine-1-carboxamide, Inhibits Mitochondria and Kills Tumor Cells under Glucose Starvation.Int J Mol Sci2020
331774904EBP1/2 are active under standard cell culture conditions to regulate the translation of specific mRNAs.Cell Death Dis2020
32351714How does mTOR sense glucose starvation? AMPK is the usual suspect.Cell Death Discov2020
30464055<i>SEC31A</i> mutation affects ER homeostasis, causing a neurological syndrome.J Med Genet2019
31511524Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.Nat Commun2019
30867410The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells.Cell Death Dis2019
30860495Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy.JCI Insight2019
30704052High-Throughput Screening Identified Compounds Sensitizing Tumor Cells to Glucose Starvation in Culture and VEGF Inhibitors In Vivo.Cancers (Basel)2019
31081944The long noncoding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells.Int J Cancer2019
29348556Puromycin labeling does not allow protein synthesis to be measured in energy-starved cells.Cell Death Dis2018
30237504IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer.Cell Death Dis2018
29903916Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation.J Biol Chem2018
29844156TAp73 contributes to the oxidative stress response by regulating protein synthesis.Proc Natl Acad Sci U S A2018
30507330Sustained protein synthesis and reduced eEF2K levels in TAp73<sup>-\-</sup> mice brain: a possible compensatory mechanism.Cell Cycle2018
28815059Erratum: Long noncoding RNA: noncoding and not coded.Cell Death Discov2017
28090356Long noncoding RNA: noncoding and not coded.Cell Death Discov2017
28696919Nomad scientists and the ones left behind.Elife2017
26829052Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.Oncogene2016
25284589Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction.Oncogene2015
25464034Stress-mediated translational control in cancer cells.Biochim Biophys Acta2015
24516159HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.Proc Natl Acad Sci U S A2014
25237759Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.Oncotarget2014
24787015High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy.Cell Death Dis2014
23706743The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.Cell2013
24342878Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers.Oncotarget2013
24280494[Surviving nutrient deprivation by restraining translation elongation: biological function of the eEF2 kinase].Med Sci (Paris)2013
23864022Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.Nat Commun2013
21804605A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.Oncogene2012
23174755NRF2 and p53: Januses in cancer?Oncotarget2012
22967496Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click-SILAC approach.J Proteomics2012
221795747th Tuscany Retreat on Cancer Research: genetic profiling, resistance mechanism and novel treatment concepts in cancer.Cell Death Differ2012
21903344A possible role for long non-coding RNA in modulating signaling pathways.Med Hypotheses2011
20700538H-Ras nanocluster stability regulates the magnitude of MAPK signal output.PLoS One2010
21203451Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition.PLoS One2010
18374183The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer.Methods Enzymol2008
18547399AtEHDs, novel Arabidopsis EH-domain-containing proteins involved in endocytosis.Plant J2008
18701484K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3.Cancer Res2008
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Collaborators

Gabriel Leprivier
Institute of Neuropathology, Heinrich-Heine University Dusseldorf
Co-authored papers 20
Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 11
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 6
Guido Reifenberger
Heinrich Heine University
Co-authored papers 6
Thomas G P Gr??newald
German Cancer Research Center
Co-authored papers 6
Daniel Picard
Groupe Hospitalier Universitaire Pitie-Salpetriere
Co-authored papers 5
Cristina E Tognon
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Arndt Borkhardt
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
Co-authored papers 3
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 3
David Pauck
German Cancer Research Center (DKFZ)
Co-authored papers 2
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 2
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 2
Thibault Mayor
Co-authored papers 2
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 2
Nan Qin
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 2
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 2
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 1
Frank Westermann
Co-authored papers 1
Richard N Kitsis
Co-authored papers 1
Antoine Forget (CM4AI)
University of California San Francisco
Co-authored papers 1
Michael R Hayden
Co-authored papers 1
Flavia Bernardi
Institut Curie, PSL Research University, CNRS UMR, INSERM
Co-authored papers 1
Gerhard Steger
Institut fur Pysikalische Biologie, Heinrich Heine University Dusseldorf
Co-authored papers 1
Didier Surdez
Balgrist University Hospital, University of Zurich (UZH)
Co-authored papers 1
Anja Stefanski
Universitatsklinikum
Co-authored papers 1
Lena Bl??mel
German Cancer Research Center (DKFZ)
Co-authored papers 1
Anthony E Oro
Stanford University
Co-authored papers 1
Martin E Gleave
University of British Columbia
Co-authored papers 1
Jennifer R Grandis
University of California san francisco
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Soumav Nath
Institut fur Physikalische Biologie, Heinrich-Heine-Universitat Dusseldorf
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Release 1.2