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Author Details

Simin Zheng
Icahn School of Medicine at Mount Sinai
2008
15
9
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37339625Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.Cell Host Microbe2023
36002837RASopathies due to de novo pathogenic variants: clinical features, genetic findings and outcomes in nine neonates born with congenital heart defects.BMC Med Genomics2022
34075878HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.Elife2021
33836156TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.Cell2021
33831416The uncharacterized SANT and BTB domain-containing protein SANBR inhibits class switch recombination.J Biol Chem2021
33970190DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells.J Exp Med2021
33970137Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches.J Vis Exp2021
33299999Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.bioRxiv2020
32084337A Quantitative Genetic Interaction Map of HIV Infection.Mol Cell2020
30411342NME proteins regulate class switch recombination.FEBS Lett2019
25957684Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA.Cell2015
24507154Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Adv Immunol2014
21186367The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA.Nat Immunol2011
21131982CtIP promotes microhomology-mediated alternative end joining during class-switch recombination.Nat Struct Mol Biol2011
17687644Anti-estrogenic mechanism of unliganded progesterone receptor isoform B in breast cancer cells.Breast Cancer Res Treat2008
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Collaborators

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NYU Grossman School of Medicine
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University of Geneva
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Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
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Icahn School of Medicine at Mount Sinai
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University of Cincinnati College of Medicine
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College of Veterinary Medicine, Kansas State University
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Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
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University of California, USA Quantitative Biosciences Institute (QBI) san francisco
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University of California, USA Quantitative Biosciences Institute (QBI) san francisco
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