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Author Details
Full Name
Simin Zheng
Affiliation
Icahn School of Medicine at Mount Sinai
ORCID
Career Start Year
2008
Papers
15
H Index
9
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37339625
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.
Cell Host Microbe
2023
36002837
RASopathies due to de novo pathogenic variants: clinical features, genetic findings and outcomes in nine neonates born with congenital heart defects.
BMC Med Genomics
2022
34075878
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Elife
2021
33836156
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
Cell
2021
33831416
The uncharacterized SANT and BTB domain-containing protein SANBR inhibits class switch recombination.
J Biol Chem
2021
33970190
DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells.
J Exp Med
2021
33970137
Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches.
J Vis Exp
2021
33299999
Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.
bioRxiv
2020
32084337
A Quantitative Genetic Interaction Map of HIV Infection.
Mol Cell
2020
30411342
NME proteins regulate class switch recombination.
FEBS Lett
2019
25957684
Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA.
Cell
2015
24507154
Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.
Adv Immunol
2014
21186367
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA.
Nat Immunol
2011
21131982
CtIP promotes microhomology-mediated alternative end joining during class-switch recombination.
Nat Struct Mol Biol
2011
17687644
Anti-estrogenic mechanism of unliganded progesterone receptor isoform B in breast cancer cells.
Breast Cancer Res Treat
2008
1 - 15 of 15
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