Author details

Full Name

Tom Alber

Affiliation

University of California berkeley

ORCID

Career Start Year

1976

Papers

131

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
33182997	Crystal Structure and Mechanistic Molecular Modeling Studies of <i>Mycobacterium tuberculosis</i> Diterpene Cyclase Rv3377c.	Biochemistry	2020
30645119	Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.	J Am Chem Soc	2019
29861345	Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.	Structure	2018
28691068	Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.	ACS Cent Sci	2017
28692281	Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA.	Biochemistry	2017
27601474	Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.	J Biol Chem	2016
25580578	The energy landscape of adenylate kinase during catalysis.	Nat Struct Mol Biol	2015
24452911	Mycobacterium tuberculosis RpfE crystal structure reveals a positively charged catalytic cleft.	Protein Sci	2014
25551456	Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.	PLoS One	2014
24843173	Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.	Proc Natl Acad Sci U S A	2014
24843025	AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.	Elife	2014
24928517	Biochemical and spatial coincidence in the provisional Ser/Thr protein kinase interaction network of Mycobacterium tuberculosis.	J Biol Chem	2014
24884374	Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation.	J Am Chem Soc	2014
24516143	Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c.	Proc Natl Acad Sci U S A	2014
24367103	AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.	Proc Natl Acad Sci U S A	2014
24363322	Protein structural ensembles are revealed by redefining X-ray electron density noise.	Proc Natl Acad Sci U S A	2014
23317505	tRNA binding, structure, and localization of the human interferon-induced protein IFIT5.	Mol Cell	2013
24309377	Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.	Proc Natl Acad Sci U S A	2013
24019530	Structural and biochemical analyses of Mycobacterium tuberculosis N-acetylmuramyl-L-alanine amidase Rv3717 point to a role in peptidoglycan fragment recycling.	J Biol Chem	2013
23471103	The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.	Elife	2013
23468634	Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria.	PLoS Pathog	2013
23251033	HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.	Proc Natl Acad Sci U S A	2013
22362775	Ferritin protein nanocage ion channels: gating by N-terminal extensions.	J Biol Chem	2012
23145064	Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.	PLoS One	2012
22727744	Structure of the sensor domain of Mycobacterium tuberculosis PknH receptor kinase reveals a conserved binding cleft.	J Mol Biol	2012
22773105	Cyclic AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis.	Nat Struct Mol Biol	2012
22275220	A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria.	Sci Signal	2012
22393408	Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.	PLoS One	2012
20708689	Purification and characterization of HIV-human protein complexes.	Methods	2011
22190034	Global landscape of HIV-human protein complexes.	Nature	2011
21788488	Hyaloperonospora arabidopsidis ATR1 effector is a repeat protein with distributed recognition surfaces.	Proc Natl Acad Sci U S A	2011
21873227	Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.	Proc Natl Acad Sci U S A	2011
21918110	Accessing protein conformational ensembles using room-temperature X-ray crystallography.	Proc Natl Acad Sci U S A	2011
21368134	Depletion of antibiotic targets has widely varying effects on growth.	Proc Natl Acad Sci U S A	2011
21190940	Solution structure of the guanine nucleotide-binding STAS domain of SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis.	J Biol Chem	2011
20230004	Dynamic active-site protection by the M. tuberculosis protein tyrosine phosphatase PtpB lid domain.	J Am Chem Soc	2010
21134645	Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.	Structure	2010
20866049	Moving metal ions through ferritin-protein nanocages from three-fold pores to catalytic sites.	J Am Chem Soc	2010
20444707	The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.	J Biol Chem	2010
20471948	HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.	Mol Cell	2010
20499387	Automated electron-density sampling reveals widespread conformational polymorphism in proteins.	Protein Sci	2010
20670276	Diterpene production in Mycobacterium tuberculosis.	FEBS J	2010
19700407	Interdomain communication in the Mycobacterium tuberculosis environmental phosphatase Rv1364c.	J Biol Chem	2009
19956261	Hidden alternative structures of proline isomerase essential for catalysis.	Nature	2009
19889539	Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.	Bioorg Med Chem Lett	2009
19914822	Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases.	Curr Opin Struct Biol	2009
19942140	Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals.	Chem Biol	2009
18698842	Targeting metastable coiled-coil domains by computational design.	J Am Chem Soc	2008
18752626	Protein tyrosine phosphatase PtpA is not required for Mycobacterium tuberculosis growth in mice.	FEMS Microbiol Lett	2008
19008858	Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase.	EMBO J	2008

1 - 50 of 131

Marc C Deller

Incyte Corporation

Career Start Year 2000

Number of shared co-authors 3

Jeffrey B Bonanno

Albert Einstein College of Medicine

Career Start Year 1999

Number of shared co-authors 6

Sergey M Vorobiev

Columbia University

Career Start Year 1998

Number of shared co-authors 2

Udupi A Ramagopal

Poornaprajna Institute of Scientific Research (PPISR)

Career Start Year 1998

Number of shared co-authors 1

Shira Albeck

Weizmann Institute of Science

Career Start Year 1996

Number of shared co-authors 6

Zihe Rao

Nankai University

Career Start Year 1995

Number of shared co-authors 6

Clemens Vonrhein

Global Phasing Ltd

Career Start Year 1995

Number of shared co-authors 0

Orly Dym

Weizmann Institute of Science

Career Start Year 1995

Number of shared co-authors 7

Diana R Tomchick

University of Texas Southwestern Medical Center

Career Start Year 1993

Number of shared co-authors 1

Youngchang Kim

Argonne National Laboratory

Career Start Year 1993

Number of shared co-authors 7

Gye Won Han

Bridge Institute, University of Southern California

Career Start Year 1991

Number of shared co-authors 2

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Career Start Year 1989

Number of shared co-authors 6

Cheryl H Arrowsmith

University of Toronto

Career Start Year 1989

Number of shared co-authors 8

Marc-Andr?? Elsliger

Joint Center for Structural Genomics

Career Start Year 1989

Number of shared co-authors 2

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 9

Liang Tong

Columbia University

Career Start Year 1988

Number of shared co-authors 6

Scott A Lesley

Merck & Co., Inc.

Career Start Year 1987

Number of shared co-authors 7

John F Hunt

Columbia University

Career Start Year 1986

Number of shared co-authors 8

Aled M Edwards

University of Toronto

Career Start Year 1984

Number of shared co-authors 7

Stephen K Burley

The State University of New Jersey

Career Start Year 1982

Number of shared co-authors 9

Vladimir N Malashkevich

Albert Einstein College of Medicine

Career Start Year 1982

Number of shared co-authors 1

John Kuriyan

University of California berkeley

Career Start Year 1982

Number of shared co-authors 4

Udo Heinemann

Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)

Career Start Year 1980

Number of shared co-authors 6

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Career Start Year 1979

Number of shared co-authors 8

George N Phillips

Rice University

Career Start Year 1974

Number of shared co-authors 2

Robert J Fletterick

University of California San Francisco

Career Start Year 1971

Number of shared co-authors 7

Tom L Blundell

Heartand Lung Research Institute, University of Cambridge

Career Start Year 1971

Number of shared co-authors 3

Wayne A Hendrickson

Columbia University

Career Start Year 1968

Number of shared co-authors 1

Sung-Hou Kim

University of California berkeley

Career Start Year 1967

Number of shared co-authors 7

Robert M Stroud

University of California San Francisco

Career Start Year 1965

Number of shared co-authors 16

row(s) 1 - 30 of 30

James M Holton

Lawrence Berkeley National Laboratory

Co-authored papers 12

Qiang Zhou

The University of Hong Kong

Co-authored papers 7

Gregory A Petsko

Helen and Robert Appel Alzheimer's Disease Research Institute, Cornell University

Co-authored papers 7

James S Fraser

University of California san francisco

Co-authored papers 7

Seemay Chou

University of California - San Francisco

Co-authored papers 7

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 6

Christina E Baer

Co-authored papers 6

Thomas C Terwilliger

Los Alamos National Laboratory

Co-authored papers 5

Ursula Schulze-Gahmen

Gladstone Institute of Virology, Gladstone Institutes San Francisco CA USA .

Co-authored papers 4

Nanhai He

Adlai Nortye USA Inc.

Co-authored papers 4

Geoffrey S Waldo

Los Alamos National Laboratory

Co-authored papers 3

Li-Wei Hung

Los Alamos National Laboratory

Co-authored papers 3

David Eisenberg

university of california los angeles

Co-authored papers 3

Yuhua Xue

School of Pharmaceutical Sciences, Xiamen University

Co-authored papers 3

Huasong Lu

Life Sciences Institute, Zhejiang University

Co-authored papers 3

Alan D Frankel

University of California san francisco

Co-authored papers 2

Peter Cimermancic

Verily Life Sciences LLC

Co-authored papers 2

Erin K O'Shea

Howard Hughes Medical Institute

Co-authored papers 2

Jeffery S Cox

University of California berkeley

Co-authored papers 2

Katherine Bao

Duke University Medical Center

Co-authored papers 2

Jason D Fernandes

University of California san francisco

Co-authored papers 2

Natali Gulbahce

Complete Genomics Inc.

Co-authored papers 2

Avi J Samelson

Institute for Neurodegenerative Diseases, University of California san francisco

Co-authored papers 2

Iv??n D'Orso

University of Texas Southwestern Medical Center

Co-authored papers 2

Chang-Yub Kim

Los Alamos National Laboratory

Co-authored papers 2

Stefanie J??ger

Institute of Molecular Biosciences, Goethe University Frankfurt

Co-authored papers 2

Min Liu

Xiamen University

Co-authored papers 2

Jeffrey R Johnson

Gladstone Institutes

Co-authored papers 2

Heather E Upton

University of California berkeley

Co-authored papers 2

Jacob E Corn

Co-authored papers 2

1 - 30

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