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Author Details

Hagai Ginsburg
The Alexander Silberman Institute of Life Science, Hebrew University of Jerusalem
1971
191
56
PMIDPaper TitleJournal TitlePublished Year
35347215Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response.Commun Biol2022
26530861Malaria Parasite Metabolic Pathways (MPMP) Upgraded with Targeted Chemical Compounds.Trends Parasitol2016
21493145Plasmodium falciparum metabolic pathways (MPMP) project upgraded with a database of subcellular locations of gene products.Trends Parasitol2011
21646484Antiplasmodial properties of acyl-lysyl oligomers in culture and animal models of malaria.Antimicrob Agents Chemother2011
21411016Analysis of additivity and synergism in the anti-plasmodial effect of purified compounds from plant extracts.Malar J2011
21411010A call for using natural compounds in the development of new antimalarial treatments - an introduction.Malar J2011
20093114Modulation of cerebral malaria by fasudil and other immune-modifying compounds.Exp Parasitol2010
20686561Metabolism: Malaria parasite stands out.Nature2010
18986839Caveat emptor: limitations of the automated reconstruction of metabolic pathways in Plasmodium.Trends Parasitol2009
19796339Membrane transport proteins of the malaria parasite.Mol Microbiol2009
19343220The homeostasis of Plasmodium falciparum-infected red blood cells.PLoS Comput Biol2009
17720165Ethnopharmacology and malaria: new hypothetical leads or old efficient antimalarials?Int J Parasitol2008
18852452The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites.Proc Natl Acad Sci U S A2008
17292372Electrophysiological studies of malaria parasite-infected erythrocytes: current status.Int J Parasitol2007
17524501Pharmacogenomic analyses of targeting the AT-rich malaria parasite genome with AT-specific alkylating drugs.Mol Biochem Parasitol2007
17307975Antiplasmodial activity of lauryl-lysine oligomers.Antimicrob Agents Chemother2007
16707126The evolution of the new permeability pathways in Plasmodium falciparum--infected erythrocytes--a kinetic analysis.Exp Parasitol2006
16986623Can biochemical properties serve as selective pressure for gene selection during inter-species and endosymbiotic lateral gene transfer?Syst Biol (Stevenage)2006
16707276Progress in in silico functional genomics: the malaria Metabolic Pathways database.Trends Parasitol2006
15728121The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum.Blood2005
16298348Arylpiperazines displaying preferential potency against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum.Biochem Pharmacol2005
16054105Should chloroquine be laid to rest?Acta Trop2005
15774020Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.Malar J2005
15734658How many functional transport pathways does Plasmodium falciparum induce in the membrane of its host erythrocyte?Trends Parasitol2005
15037104Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions.Int J Parasitol2004
15245577Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome.Malar J2004
15014913The new permeability pathways induced by the malaria parasite in the membrane of the infected erythrocyte: comparison of results using different experimental techniques.J Membr Biol2004
15121091Excess haemoglobin digestion by malaria parasites: a strategy to prevent premature host cell lysis.Blood Cells Mol Dis2004
12519984PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data.Nucleic Acids Res2003
14962364Glutathione is involved in the antimalarial action of chloroquine and its modulation affects drug sensitivity of human and murine species of Plasmodium.Redox Rep2003
14962354Redox metabolism in malaria: from genes, through biochemistry and pathology, to drugs.Redox Rep2003
12948862Potentiation of the antimalarial action of chloroquine in rodent malaria by drugs known to reduce cellular glutathione levels.Biochem Pharmacol2003
12658456Killing of intraerythrocytic Plasmodium falciparum by lysosomotropic amino acid esters.Parasitol Res2003
12669348The treatment of Plasmodium falciparum-infected erythrocytes with chloroquine leads to accumulation of ferriprotoporphyrin IX bound to particular parasite proteins and to the inhibition of the parasite's 6-phosphogluconate dehydrogenase.Parasite2003
12763422The mysteries of hemoglobin degradation in Plasmodium falciparum-infected erythrocytes.Trends Parasitol2003
12531811Excess hemoglobin digestion and the osmotic stability of Plasmodium falciparum-infected red blood cells.Blood2003
11937508Direct interaction of dermaseptin S4 aminoheptanoyl derivative with intraerythrocytic malaria parasite leading to increased specific antiparasitic activity in culture.J Biol Chem2002
12377282Oxidative permeabilization?Trends Parasitol2002
12368860The Plasmodium genome database.Nature2002
12128052A non-radiolabelled ferriprotoporphyrin IX biomineralisation inhibition test for the high throughput screening of antimalarial compounds.Exp Parasitol2002
12495436Is the development of falciparum malaria in the human host limited by the availability of uninfected erythrocytes?Malar J2002
12473363Abundant proton pumping in Plasmodium falciparum, but why?Trends Parasitol2002
11998701Do azoles and chloroquine share similar mechanisms of antimalarial action?Trends Parasitol2002
11814576Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins.Mol Biochem Parasitol2002
11897590In vitro antiplasmodium effects of dermaseptin S4 derivatives.Antimicrob Agents Chemother2002
11854079A double-headed pro-drug that overcomes chloroquine resistance.Trends Parasitol2002
11811806Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine.Parasitology2002
11853690Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes.Biochem Pharmacol2002
11606226Transglutaminase in Plasmodium parasites: activity and putative role in oocysts and blood stages.Mol Biochem Parasitol2001
11676365Pharmacokinetic-pharmacodynamic modelling of the antimalarial activity of mefloquine.Parasitology2001
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Collaborators

Zbynek Bozdech
Nanyang Technological University
Co-authored papers 4
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Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 2
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University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
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Co-authored papers 2
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University Hospitals Bristol and Weston NHS Foundation Trust
Co-authored papers 2
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Co-authored papers 2
Jessica C Kissinger
University of Georgia
Co-authored papers 2
Patricia L Whetzel
University of Colorado Anschutz Medical Campus
Co-authored papers 2
David S Pearson
Co-authored papers 2
Arthur J Milgram
Co-authored papers 2
Bindu Gajria
University of Pennsylvania
Co-authored papers 2
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Co-authored papers 2
Dinesh Gupta
International Centre for Genetic Engineering and Biotechnology (ICGEB)
Co-authored papers 2
Matthew D Mailman
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 2
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University of Pennsylvania
Co-authored papers 2
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University of Pennsylvania
Co-authored papers 2
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Co-authored papers 2
Martin Fraunholz
Julius-Maximilians-Universitat Wurzburg
Co-authored papers 2
Sharon J Diskin
Children's Hospital of Philadelphia
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Jane M Carlton
Center for Genomics and Systems Biology
Co-authored papers 1
Release 1.2