Author details

Full Name

John C Hedreen

Affiliation

ORCID

Career Start Year

1972

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33188775	Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease.	Cell	2020
30482917	Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.	Nat Neurosci	2019
29496141	What can we learn about brain donors? Use of clinical information in human postmortem brain research.	Handbook of Clinical Neurology	2018
30224808	Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.	Nat Neurosci	2018
22804696	Laminar distribution of the pathological changes in sporadic frontotemporal lobar degeneration with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy: a quantitative study using polynomial curve fitting.	Neuropathol Appl Neurobiol	2013
22452578	Critical role of truncated Î±-synuclein and aggregates in Parkinson's disease and incidental Lewy body disease.	Brain Pathology	2012
20012109	Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis.	J Neural Transm (Vienna)	2010
20926834	PGC-1Î±, a potential therapeutic target for early intervention in Parkinson's disease.	Sci Transl Med	2010
16938275	TorsinB expression in the developing human brain.	Brain Res	2006
15965202	HIV leucoencephalopathy and TNFalpha expression in neurones.	J Neurol Neurosurg Psychiatry	2005
15939081	TorsinA expression is detectable in human infants as young as 4 weeks old.	Brain Res Dev Brain Res	2005
15304590	Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia.	Neurology	2004
12834106	SDF-1alpha is expressed in astrocytes and neurons in the AIDS dementia complex: an in vivo and in vitro study.	Journal of Neuropathology and Experimental Neurology	2003
12609485	TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion.	Neurobiol Dis	2003
11711205	Tau protein expression in frontotemporal dementias.	Neuroscience Letters	2001
11175326	NFkappaB activation, TNF-alpha expression, and apoptosis in the AIDS-Dementia-Complex.	Journal of NeuroVirology	2000
10407418	Unbiased stereology?	Trends in Neurosciences	1999
10443886	Human immunodeficiency virus infection, inducible nitric oxide synthase expression, and microglial activation: pathogenetic relationship to the acquired immunodeficiency syndrome dementia complex.	Annals of Neurology	1999
10379826	Tyrosine hydroxylase-immunoreactive elements in the human globus pallidus and subthalamic nucleus.	Journal of Comparative Neurology	1999
9517853	Lost caps in histological counting methods.	Anatomical Record	1998
9517854	What was wrong with the Abercrombie and empirical cell counting methods? A review.	Anatomical Record	1998
9351236	Centenary of Gaule and Lewin, pioneers in cell counting methodology.	Journal of Microscopy	1997
8659522	Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.	American Journal of Human Genetics	1996
8939276	Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer disease neuropathology.	Alzheimer Dis Assoc Disord	1996
8929997	Lack of association of the apoE4 allele with hippocampal sclerosis dementia.	Neuroscience Letters	1996
7711729	Expression of the mutant allele of IT-15 (the HD gene) in striatum and cortex of Huntington's disease patients.	Human Molecular Genetics	1995
7751945	Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.	Journal of Neuroscience	1995
7898697	The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease.	Neurology	1995
7815073	Early loss of neostriatal striosome neurons in Huntington's disease.	Journal of Neuropathology and Experimental Neurology	1995
7794478	Comparison of new and traditional methods for detection of senile plaques in Alzheimer's disease.	Journal of Geriatric Psychiatry and Neurology	1995
7651448	Neuronal loss from the subthalamic nuclei in a patient with progressive chorea.	Movement Disorders	1995
7812810	A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections.	Brain Research Bulletin	1994
7523595	RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue.	Journal of Neurochemistry	1994
7515353	Selective loss of [3H]kainic acid and [3H]AMPA binding in layer VI of frontal cortex in Huntington's disease.	Experimental Neurology	1994
7964906	Phosphorylated neurofilaments in neuronal perikarya and dendrites in human brain following axonal damage.	Journal of Neuropathology and Experimental Neurology	1994
8492957	The locus ceruleus and dementia in Parkinson's disease.	Neurology	1993
1531288	Locus coeruleus involvement in Huntington's disease.		1992
2013650	Organization of striatopallidal, striatonigral, and nigrostriatal projections in the macaque.	J Comp Neurol	1991
1985156	Hippocampal lesions in dominantly inherited Alzheimer's disease.	Journal of Neuropathology and Experimental Neurology	1991
1682006	Reductions in acidic amino acids and N-acetylaspartylglutamate in amyotrophic lateral sclerosis CNS.	Brain Res	1991
1840078	Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease.	Neuroscience Letters	1991
2146140	Nigral dopamine type-1 receptors are reduced in Huntington's disease: a postmortem autoradiographic study using [3H]SCH 23390 and correlation with [3H]forskolin binding.	Exp Neurol	1990
2549845	The pedunculopontine nucleus in Parkinson's disease.	Annals of Neurology	1989
2528319	Linkage to the Huntington's disease locus in a family with unusual clinical and pathological features.	Annals of Neurology	1989
2602423	Neuropathology of aminergic nuclei in Alzheimer's disease.	Progress in Clinical and Biological Research	1989
2459566	Selective silver impregnation of senile plaques: a method useful for computer imaging.	Journal of Neuroscience Methods	1988
3362365	Pathology in brainstem regions of individuals with primary dystonia.	Neurology	1988
3178178	The neuropathology of aminergic nuclei in Alzheimer's disease.	Annals of Neurology	1988
3041757	Primary dystonias: a review of the pathology and suggestions for new directions of study.	Adv Neurol	1988
3278549	Brain stem pathology in cranial dystonia.	Advances in neurology	1988