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Author Details

Michael Boutros
German Cancer Research Center (DKFZ) and Heidelberg University
1995
220
65
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36938773Engaging European society at the forefront of cancer research and care: How discussions at the 5<sup>th</sup> Gago Conference on European Science policy led to the Heidelberg ManifestoMol Oncol2023
37903161The pleiotropic functions of Pri smORF peptides synchronize leg development regulators.PLoS Genet2023
37647411A temperature-tolerant CRISPR base editor mediates highly efficient and precise gene editing in <i>Drosophila</i>.Sci Adv2023
37494060Glyoxal as an alternative fixative for single-cell RNA sequencing.G3 (Bethesda)2023
37421942Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2.Mol Cell2023
37116498A global genetic interaction network by single-cell imaging and machine learning.Cell Syst2023
36982422The Roles of Secreted Wnt Ligands in Cancer.Int J Mol Sci2023
37271243Intestinal stem cells and their niches in homeostasis and disease.Cells Dev2023
36749823USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.Sci Signal2023
36746786A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase.Chromosoma2023
36763105The role of Evi/Wntless in exporting Wnt proteins.Development2023
35196315Correction: Bacterial recognition by PGRP-SA and downstream signalling by Toll/DIF sustain commensal gut bacteria in Drosophila.PLoS Genet2022
35606086Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.J Immunother Cancer2022
35666536Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors.Int J Cancer2022
36074491UNCAN.eu, a European Initiative to UNderstand CANcer.Cancer Discov2022
35904277Metabolic balance in colorectal cancer is maintained by optimal Wnt signaling levels.Mol Syst Biol2022
35867833Superresolution microscopy localizes endogenous Dvl2 to Wnt signaling-responsive biomolecular condensates.Proc Natl Acad Sci U S A2022
36293109Blockade of Wnt Secretion Attenuates Myocardial Ischemia-Reperfusion Injury by Modulating the Inflammatory Response.Int J Mol Sci2022
35980577Tissue-Specific CRISPR-Cas9 Screening in Drosophila.Methods Mol Biol2022
35014953Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells.Elife2022
35247870Artificial intelligence for detection of microsatellite instability in colorectal cancer-a multicentric analysis of a pre-screening tool for clinical application.ESMO Open2022
35007276Bacterial recognition by PGRP-SA and downstream signalling by Toll/DIF sustain commensal gut bacteria in Drosophila.PLoS Genet2022
32926374Cloud-Based Design of Short Guide RNA (sgRNA) Libraries for CRISPR Experiments.Methods Mol Biol2021
33666175Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies.Elife2021
33551307The Role of Organelles in Intestinal Function, Physiology, and Disease.Trends Cell Biol2021
34406391EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2.J Cell Sci2021
34831379Conditional CRISPR-Cas Genome Editing in <i>Drosophila</i> to Generate Intestinal Tumors.Cells2021
34038707A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver.Dev Cell2021
34118087The extracellular matrix proteins type I collagen, type III collagen, fibronectin, and laminin 421 stimulate migration of cancer cells.FASEB J2021
34197724Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth.Dev Cell2021
34026331PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells.Oncoimmunology2021
33186476Multi-omics integration identifies a selective vulnerability of colorectal cancer subtypes to YM155.Int J Cancer2021
33353984Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung.Nature2021
33207034Extracellular vesicles and oncogenic signaling.Mol Oncol2021
32567155Ageing, metabolism and the intestine.EMBO Rep2020
33228647Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library.BMC Biol2020
33257473Wnt10b-GSK3β-dependent Wnt/STOP signaling prevents aneuploidy in human somatic cells.Life Sci Alliance2020
32665263CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti-PD-L1 Treatment.Cancer Immunol Res2020
32764203Cancer-Associated Mutations in Normal Colorectal Mucosa Adjacent to Sporadic Neoplasia.Clin Transl Gastroenterol2020
32843348Multiplexed conditional genome editing with Cas12a in <i>Drosophila</i>.Proc Natl Acad Sci U S A2020
32122365gscreend: modelling asymmetric count ratios in CRISPR screens to decrease experiment size and improve phenotype detection.Genome Biol2020
32339205Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila.PLoS Pathog2020
32244184'Corrigendum to "Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia" [Molecular Metabolism 5 (2) (2015) 67-78]'.Mol Metab2020
32277031JNK-dependent intestinal barrier failure disrupts host-microbe homeostasis during tumorigenesis.Proc Natl Acad Sci U S A2020
32381507eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled.J Biol Chem2020
32348727Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids.Cell Stem Cell2020
32227170Gut Microbiota-Derived Propionate Regulates the Expression of Reg3 Mucosal Lectins and Ameliorates Experimental Colitis in Mice.J Crohns Colitis2020
29673923CRISPR/Cas9 for cancer research and therapy.Semin Cancer Biol2019
31877768miR-10a-5p and miR-29b-3p as Extracellular Vesicle-Associated Prostate Cancer Detection Markers.Cancers (Basel)2019
31527874Exocyst-mediated apical Wg secretion activates signaling in the Drosophila wing epithelium.PLoS Genet2019
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Collaborators

Wolfgang Huber
Technische Universitat Munchen
Co-authored papers 14
Norbert Perrimon
Co-authored papers 10
Kerstin Spirohn
Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute
Co-authored papers 8
Timo Gaiser
Institut fur Pathologie, Universitatsmedizin Mannheim
Co-authored papers 5
Antonio Sorrentino
Leibniz Institute for Immunotherapy (LIT)
Co-authored papers 3
Jules A Hoffmann
Sino-French Hoffmann Institute, Guangzhou Medical University
Co-authored papers 3
Rainer Spang
University of Regensburg
Co-authored papers 3
Sven Diederichs
Medical Center - University of Freiburg, University of Freiburg
Co-authored papers 3
Peter Schirmacher
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 2
Thomas Eschenhagen
Co-authored papers 2
Thomas Longerich
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 2
Lars M Steinmetz
Stanford University
Co-authored papers 2
George M Church
Harvard Medical School
Co-authored papers 1
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 1
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
F??tima Carneiro
Centro Hospitalar Universitario de Sao Joao.
Co-authored papers 1
Matias Simons
Institute of Human Genetics, University Hospital Heidelberg
Co-authored papers 1
Stefan Wiemann
Co-authored papers 1
Chieko Makino-Okamura
Biosignal Research Center, Kobe University
Co-authored papers 1
Julie Ahringer
Co-authored papers 1
Christian Haass
German Center for Neurodegenerative Diseases (DZNE) Munich
Co-authored papers 1
Yongsheng Guan
College of Information Engineering, Xijing University
Co-authored papers 1
Jan Ellenberg
Institute of Child Health and Human Development
Co-authored papers 1
Jenny Chang-Claude
German Cancer Research Center (DKFZ)
Co-authored papers 1
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 1
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 1
Charles Hetru
CNRS UPR2, Institut de Biologie Moleculaire et Cellulaire
Co-authored papers 1
Carles Pons
Co-authored papers 1
Elie Maksoud
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Release 1.2