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Author Details

Chen Wang
Center for Individualized Medicine, Mayo Clinic
2011
101
29
PMIDPaper TitleJournal TitlePublished Year
38037121Enabling the clinical application of artificial intelligence in genomics: a perspective of the AMIA Genomics and Translational Bioinformatics Workgroup.J Am Med Inform Assoc2024
36322906Excerno: Using Mutational Signatures in Sequencing Data to Filter False Variants Caused by Clinical Archival.J Comput Biol2023
36948887p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study.J Pathol Clin Res2023
36960831Multiplex Immunofluorescence Image Quality Checking Using DAPI Channel-referenced Evaluation.J Histochem Cytochem2023
36790339Methylation Signature Implicated in Immuno-Suppressive Activities in Tubo-Ovarian High-Grade Serous Carcinoma.Cancer Epidemiol Biomarkers Prev2023
36572991CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.Cancer2023
34592239Morphological heterogeneity in beta-catenin-mutated hepatocellular carcinomas: implications for tumor molecular classification.Hum Pathol2022
35673010POKR: Building a Computable Heterogeneous Knowledge Resource for Precision Oncology.Stud Health Technol Inform2022
36456881The genomic and immune landscape of long-term survivors of high-grade serous ovarian cancer.Nat Genet2022
35907849PO2RDF: representation of real-world data for precision oncology using resource description framework.BMC Med Genomics2022
36262887Machine learning models identify ferroptosis-related genes as potential diagnostic biomarkers for Alzheimer's disease.Front Aging Neurosci2022
36222570Leveraging a pharmacogenomics knowledgebase to formulate a drug response phenotype terminology for genomic medicine.Bioinformatics2022
36160147Computational tumor stroma reaction evaluation led to novel prognosis-associated fibrosis and molecular signature discoveries in high-grade serous ovarian carcinoma.Front Med (Lausanne)2022
36114500Quality control recommendations for RNASeq using FFPE samples based on pre-sequencing lab metrics and post-sequencing bioinformatics metrics.BMC Med Genomics2022
35311903Correction to: Characterizing phenotypic abnormalities associated with high-risk individuals developing lung cancer using electronic health records from the All of Us researcher workbench.J Am Med Inform Assoc2022
34697060DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.Cancer Epidemiol Biomarkers Prev2022
34783177PSMA as a Theranostic Target in Hepatocellular Carcinoma: Immunohistochemistry and <sup>68</sup> Ga-PSMA-11 PET Using Cyclotron-Produced <sup>68</sup> Ga.Hepatol Commun2022
34782936MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.Virchows Arch2022
33160272Modeling cancer clinical trials using HL7 FHIR to support downstream applications: A case study with colorectal cancer data.Int J Med Inform2021
33648520Determining mutational burden and signature using RNA-seq from tumor-only samples.BMC Med Genomics2021
34505903Characterizing phenotypic abnormalities associated with high-risk individuals developing lung cancer using electronic health records from the All of Us researcher workbench.J Am Med Inform Assoc2021
34447604Digital Pathology-based Study of Cell- and Tissue-level Morphologic Features in Serous Borderline Ovarian Tumor and High-grade Serous Ovarian Cancer.J Pathol Inform2021
34032581Leveraging Genetic Reports and Electronic Health Records for the Prediction of Primary Cancers: Algorithm Development and Validation Study.JMIR Med Inform2021
34261476Somatic mutations in benign breast disease tissues and association with breast cancer risk.BMC Med Genomics2021
342568182dFDR: a new approach to confounder adjustment substantially increases detection power in omics association studies.Genome Biol2021
31675340Semi-Supervised Topological Analysis for Elucidating Hidden Structures in High-Dimensional Transcriptome Datasets.IEEE/ACM Trans Comput Biol Bioinform2021
33407429Generating real-world evidence from unstructured clinical notes to examine clinical utility of genetic tests: use case in BRCAness.BMC Med Inform Decis Mak2021
31527166Dilution of Molecular-Pathologic Gene Signatures by Medically Associated Factors Might Prevent Prediction of Resection Status After Debulking Surgery in Patients With Advanced Ovarian Cancer.Clin Cancer Res2020
31787246Combining copy number, methylation markers, and mutations as a panel for endometrial cancer detection via intravaginal tampon collection.Gynecol Oncol2020
31797631Coverage profile correction of shallow-depth circulating cell-free DNA sequencing via multidistance learning.Pac Symp Biocomput2020
32663198Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma.J Clin Invest2020
32646966The YAP-Interacting Phosphatase SHP2 Can Regulate Transcriptional Coactivity and Modulate Sensitivity to Chemotherapy in Cholangiocarcinoma.Mol Cancer Res2020
32477698Developing a FHIR-based Framework for Phenome Wide Association Studies: A Case Study with A Pan-Cancer Cohort.AMIA Jt Summits Transl Sci Proc2020
32477695Data-driven Sublanguage Analysis for Cancer Genomics Knowledge Modeling: Applications in Mining Oncological Genetics Information from Patients' Genetic Reports.AMIA Jt Summits Transl Sci Proc2020
32554541Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).Clin Cancer Res2020
32134686Developing an FHIR-Based Computational Pipeline for Automatic Population of Case Report Forms for Colorectal Cancer Clinical Trials Using Electronic Health Records.JCO Clin Cancer Inform2020
30503050Mesenchymal molecular subtype is an independent predictor of severe postoperative complications after primary debulking surgery for advanced ovarian cancer.Gynecol Oncol2019
32025655Developing a scalable FHIR-based clinical data normalization pipeline for standardizing and integrating unstructured and structured electronic health record data.JAMIA Open2019
31204077Genes associated with bowel metastases in ovarian cancer.Gynecol Oncol2019
31477010Bioinformatics and DNA-extraction strategies to reliably detect genetic variants from FFPE breast tissue samples.BMC Genomics2019
31004097Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts.Sci Rep2019
30973937Use of FFPE-derived DNA in next generation sequencing: DNA extraction methods.PLoS One2019
30576442Molecular signatures of X chromosome inactivation and associations with clinical outcomes in epithelial ovarian cancer.Hum Mol Genet2019
30448260Cancer-associated stroma significantly contributes to the mesenchymal subtype signature of serous ovarian cancer.Gynecol Oncol2019
29434467Genomic Analysis Using Regularized Regression in High-Grade Serous Ovarian Cancer.Cancer Inform2018
29967001Transcriptomic Characterization of Endometrioid, Clear Cell, and High-Grade Serous Epithelial Ovarian Carcinoma.Cancer Epidemiol Biomarkers Prev2018
29932737Improving Single-Nucleotide Polymorphism-Based Fetal Fraction Estimation of Maternal Plasma Circulating Cell-Free DNA Using Bayesian Hierarchical Models.J Comput Biol2018
30062862Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.J Pathol Clin Res2018
29925470Factors that influence survival in high-grade serous ovarian cancer: A complex relationship between molecular subtype, disease dissemination, and operability.Gynecol Oncol2018
30577744Detection and visualization of complex structural variants from long reads.BMC Bioinformatics2018
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Collaborators

Ellen L Goode
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Stacey J Winham
Mayo Clinic
Co-authored papers 22
Gottfried E Konecny
David Geffen School of Medicine at University of California Los Angeles
Co-authored papers 16
Brooke L Fridley
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Co-authored papers 16
Guoqian Jiang
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Boris Winterhoff
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Paul D P Pharoah
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Yan W Asmann
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Jenny Lester
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Simon A Gayther
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Beth Y Karlan
David Geffen School of Medicine, University of California los angeles
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Ann L Oberg
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Joellen M Schildkraut
Rollins School of Public Health, Emory University
Co-authored papers 8
Stefan Kommoss
Eberhard Karls University Tubingen
Co-authored papers 8
Hongfang Liu
Mayo Clinic
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David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers 8
Martin K??bel
University of Calgary
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Catherine J Kennedy
The Westmead Institute for Medical Research, University of Sydney
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Peter A Fasching
Otto-Friedrich-University Bamberg
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Marc T Goodman
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
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James D Brenton
CRUK Cambridge Institute, University of Cambridge
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Paul Harnett
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Michael T Zimmermann
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