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Author Details

Sunil Thomas
Lankenau Institute for Medical Research
2004
46
20
PMIDPaper TitleJournal TitlePublished Year
37521457Gut-brain connections in neurodegenerative disease: immunotherapeutic targeting of Bin1 in inflammatory bowel disease and Alzheimer's disease.Front Pharmacol2023
36322599Bin1 targeted immunotherapy alters the status of the enteric neurons and the microbiome during ulcerative colitis treatment.PLoS One2022
34182794Mapping the Nonstructural Transmembrane Proteins of Severe Acute Respiratory Syndrome Coronavirus 2.J Comput Biol2021
33622713IDO1 Signaling through GCN2 in a Subpopulation of Gr-1<sup>+</sup> Cells Shifts the IFNγ/IL6 Balance to Promote Neovascularization.Cancer Immunol Res2021
32542496Association Between US Administration Endorsement of Hydroxychloroquine for COVID-19 and Outpatient Prescribing.J Gen Intern Med2020
33301441Retinoic acid improves baseline barrier function and attenuates TNF-α-induced barrier leak in human bronchial epithelial cell culture model, 16HBE 14o.PLoS One2020
33154981The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter SemiSWEET.Pathog Immun2020
32985670Epithelial barrier function properties of the 16HBE14o- human bronchial epithelial cell culture model.Biosci Rep2020
32527143An engraved surface induces weak adherence and high proliferation of nonadherent cells and microorganisms during culture.Biotechniques2020
30371803Immune Correlates of Protection From West Nile Virus Neuroinvasion and Disease.J Infect Dis2019
31727242Reliable detection of indoleamine 2,3 dioxygenase-1 in murine cells and tissues.Methods Enzymol2019
31211444Bin1 antibody lowers the expression of phosphorylated Tau in Alzheimer's disease.J Cell Biochem2019
30835899Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis.J Leukoc Biol2019
30269357Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis.J Cell Biochem2019
31156296Spontaneous and cytokine-induced hole formation in epithelial cell layers: Implications for barrier function studies with the gingival cell culture, Gie-3B11, and other epithelial models.Trends Cell Mol Biol2018
30254983Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer.Front Oncol2018
28592649Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross.G3 (Bethesda)2017
28278250Zinc reduces epithelial barrier compromise induced by human seminal plasma.PLoS One2017
28292977The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists.Cancer Res2017
29172516Improvement of Human-Oral-Epithelial-Barrier Function and of Tight Junctions by Micronutrients.J Agric Food Chem2017
26195312Novel Colitis Immunotherapy Targets Bin1 and Improves Colon Cell Barrier Function.Dig Dis Sci2016
27872814Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population.Genom Data2016
27843766Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model.Genom Data2016
27806117A Mouse Model of Chronic West Nile Virus Disease.PLoS Pathog2016
27076165Cancer Vaccines: A Brief Overview.Methods Mol Biol2016
27076151Development of Structure-Based Vaccines for Ehrlichiosis.Methods Mol Biol2016
27076124Future Challenges for Vaccinologists.Methods Mol Biol2016
25944860Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes.mBio2015
24123235Specific in situ detection of murine indoleamine 2, 3-dioxygenase.J Cell Biochem2014
25253340Activation of the RIG-I pathway during influenza vaccination enhances the germinal center reaction, promotes T follicular helper cell induction, and provides a dose-sparing effect and protective immunity.J Virol2014
24711084Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer.Cancer Immunol Immunother2014
23980113Short-lived effector CD8 T cells induced by genetically attenuated malaria parasite vaccination express CD11c.Infect Immun2013
24090172Vaccines based on structure-based design provide protection against infectious diseases.Expert Rev Vaccines2013
24144475Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis.Vaccine2013
22114733Structure-based vaccines provide protection in a mouse model of ehrlichiosis.PLoS One2011
22030371Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis.Clin Vaccine Immunol2011
20140199IPS-1 is essential for the control of West Nile virus infection and immunity.PLoS Pathog2010
21187937Exit mechanisms of the intracellular bacterium Ehrlichia.PLoS One2010
19493209Antigenic protein modifications in Ehrlichia.Parasite Immunol2009
18250406Cutting edge: progesterone regulates IFN-alpha production by plasmacytoid dendritic cells.J Immunol2008
17442964Antigen presentation by nonhemopoietic cells amplifies clonal expansion of effector CD8 T cells in a pathogen-specific manner.J Immunol2007
17715226Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.J Virol2007
16849484Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.J Immunol2006
16724117T-cell tolerance or function is determined by combinatorial costimulatory signals.EMBO J2006
16129706Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection.J Exp Med2005
15322173Proliferation and differentiation of CD8+ T cells in the absence of IL-2/15 receptor beta-chain expression or STAT5 activation.J Immunol2004
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Collaborators

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Co-authored papers 6
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Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 4
Fred Hutchinson Cancer Research Center
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 3
Fred Hutchinson Cancer Research Center
Co-authored papers 3
University of North Carolina at Chapel Hill.
Co-authored papers 2
Regeneron Pharmaceuticals
Co-authored papers 2
University of North Carolina
Co-authored papers 2
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Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
University of Washington
Co-authored papers 2
Knight Cancer Institute Oregon Health & Science University Portland Oregon USA.
Co-authored papers 2
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 1
Emory University School of Medicinegrid.471395.d
Co-authored papers 1
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Co-authored papers 1
Centers for Disease Control and Prevention.
Co-authored papers 1
University of Washington
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Fred Hutchinson Cancer Research Center
Co-authored papers 1
University College Cork
Co-authored papers 1
Wistar Institute
Co-authored papers 1
Perelman School of Medicine, The University of Pennsylvania
Co-authored papers 1