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Author Details

Jichun Chen
and Blood Institute, National Institutes of Health
1996
72
29
PMIDPaper TitleJournal TitlePublished Year
35895513Granulocytic myeloid-derived suppressor cells to prevent and treat murine immune-mediated bone marrow failure.Blood Adv2023
37834110Immunosuppressive Activity of Exosomes from Granulocytic Myeloid-Derived Suppressor Cells in a Murine Model of Immune Bone Marrow Failure.Int J Mol Sci2023
37468118Effects of ruxolitinib on murine regulatory T cells are immune-context dependent.Exp Hematol2023
36130301Efficacy of JAK1/2 inhibition in murine immune bone marrow failure.Blood2023
34763024Residual effects of busulfan and irradiation on murine hematopoietic stem and progenitor cells.Exp Hematol2022
33270949Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults.Stem Cells2021
33711076Minimal role of interleukin 6 and toll-like receptor 2 and 4 in murine models of immune-mediated bone marrow failure.PLoS One2021
32961298Dnmt3a-null hematopoietic stem and progenitor cells expand after busulfan treatment.Exp Hematol2020
31898340Attenuation of immune-mediated bone marrow damage in conventionally housed mice.Mol Carcinog2020
32858886Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression.Int J Mol Sci2020
30316805Interleukin-18 plays a dispensable role in murine and likely also human bone marrow failure.Exp Hematol2019
28741793Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.Liver Int2018
30042151Mouse Homolog of the Human TP53 R337H Mutation Reveals Its Role in Tumorigenesis.Cancer Res2018
30361263Macrophage TNF-α licenses donor T cells in murine bone marrow failure and can be implicated in human aplastic anemia.Blood2018
29524567PD-1 deficiency augments bone marrow failure in a minor-histocompatibility antigen mismatch lymphocyte infusion model.Exp Hematol2018
28620625Hematopoietic Aging Biomarkers in <i>Peromyscus leucopus</i> Mice.J Aging Sci2017
28729300Rapamycin is highly effective in murine models of immune-mediated bone marrow failure.Haematologica2017
26956117Erratum to: Low ambient oxygen prevents atherosclerosis.J Mol Med (Berl)2016
26589913PPARγ antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function.Haematologica2016
27118043Long-term adaptation to hypoxia preserves hematopoietic stem cell function.Exp Hematol2016
26830628Low ambient oxygen prevents atherosclerosis.J Mol Med (Berl)2016
25555453Immune-mediated bone marrow failure in C57BL/6 mice.Exp Hematol2015
26491068IFN-γ-mediated hematopoietic cell destruction in murine models of immune-mediated bone marrow failure.Blood2015
26388434Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells.Stem Cells2015
26354756Identification of novel microRNA signatures linked to acquired aplastic anemia.Haematologica2015
26523501Hematopoietic lineage skewing and intestinal epithelia degeneration in aged mice with telomerase RNA component deletion.Exp Gerontol2015
25962353Cloning and molecular characterization of telomerase reverse transcriptase (TERT) and telomere length analysis of Peromyscus leucopus.Gene2015
25116892Peromyscus leucopus mice: a potential animal model for haematological studies.Int J Exp Pathol2014
23619564Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy.Leukemia2013
24216172Aplastic anemia: what have we learned from animal models and from the clinic.Semin Hematol2013
22537155Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura.J Thromb Haemost2012
21635935MHC class II upregulation and colocalization with Fas in experimental models of immune-mediated bone marrow failure.Exp Hematol2011
21523336Hematopoietic stem cell development, aging and functional failure.Int J Hematol2011
19525987TBI with lung dose reduction does not improve hematopoietic cell homing to BM during allogeneic transplantation.Bone Marrow Transplant2010
20733158Th17 immune responses contribute to the pathophysiology of aplastic anemia.Blood2010
20647571Hematopoiesis in 3 dimensions: human and murine bone marrow architecture visualized by confocal microscopy.Blood2010
19903901The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failure.Blood2010
19679885Phenotypic and functional characterization of a mouse model of targeted Pig-a deletion in hematopoietic cells.Haematologica2010
19216020Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.Exp Hematol2009
19404261Bmi1 regulates mitochondrial function and the DNA damage response pathway.Nature2009
19120358Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4.Br J Haematol2009
19265119Lymphocytes with aberrant expression of Fas or Fas ligand attenuate immune bone marrow failure in a mouse model.J Immunol2009
17947508Effects of dietary restriction on hematopoietic stem-cell aging are genetically regulated.Blood2008
18562080Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice.Exp Hematol2008
18250226Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro.Blood2008
17185390Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background.Hum Mol Genet2007
17690294Augmented Wnt signaling in a mammalian model of accelerated aging.Science2007
17371972Minor antigen h60-mediated aplastic anemia is ameliorated by immunosuppression and the infusion of regulatory T cells.J Immunol2007
17156857Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.J Neuroimmunol2007
16435298Telomerase: not just for the elongation of telomeres.Bioessays2006
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Collaborators

Neal S Young
National Heart Lung and Blood Institute Division of Intramural Research
Co-authored papers 40
Xingmin Feng
and Blood Institute, National Institutes of Health
Co-authored papers 23
Zhijie Wu
and Blood Institute, National Institutes of Health
Co-authored papers 8
Shouguo Gao
and Blood Institute, National Institutes of Health
Co-authored papers 3
Shurjo K Sen
Louisiana State University
Co-authored papers 2
Vishal Thovarai
Center for Cancer Research
Co-authored papers 2
Nalini Raghavachari
Division of Geriatrics & Clinical Gerontology, National Institute on Aging
Co-authored papers 2
Beverly A Mock
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Shuling Zhang
School of Public Health, Guizhou Medical University
Co-authored papers 2
Sonia Ahluwalia
University of Michigan - Ann Arbor
Co-authored papers 1
Tyler Peat
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Jun Li
and Blood Institute, National Institutes of Health
Co-authored papers 1
Stefania Pittaluga
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Tyler Peat
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Neal S Young
and Blood Institute, National Institutes of Health
Co-authored papers 1
James G Taylor
Center for Sickle Cell Disease, Howard University College of Medicine
Co-authored papers 1
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Harvey G Klein
Clinical Center, National Institutes of Health
Co-authored papers 1
Jorge Silvio Gutkind
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Peter J Munson
and Blood Institute, National Institutes of Health
Co-authored papers 1
David M Bodine
Co-authored papers 1
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Christopher S Hourigan
and Blood Institute, National Institutes of Health
Co-authored papers 1
Mark Raffeld
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Wendy Dubois
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Sharon A Savage
Clinical Genetics Branch, National Cancer Institute (NCI)
Co-authored papers 1
Wendy Dubois
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Jinguo Chen
Center for Human Immunology
Co-authored papers 1
Release 1.2