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Author Details
Full Name
Ralf Kittler
Affiliation
McDermott Center for Human Growth and Development.
ORCID
Career Start Year
1984
Papers
67
H Index
34
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36330954
Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.
Cancer Lett
2023
37035141
Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers.
Front Oncol
2023
36780194
ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma.
Clin Cancer Res
2023
36454649
Global chromatin landscapes identify candidate noncoding modifiers of cardiac rhythm.
J Clin Invest
2023
34782721
Correction to: Hormonal modulation of ESR1 mutant metastasis.
Oncogene
2022
33096336
Dynamic differences between DNA damage repair responses in primary tumors and cell lines.
Transl Oncol
2021
34580063
Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence.
Cancer Res
2021
34752753
Structure-based classification of EGFR mutations informs inhibitor selection for lung cancer therapy.
Cancer Cell
2021
34301758
Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.
Cancer Res
2021
34011560
Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER<sup>+</sup> Breast Cancer.
Clin Cancer Res
2021
32485222
Mithramycin suppresses DNA damage repair via targeting androgen receptor in prostate cancer.
Cancer Lett
2020
31839537
GCNA Preserves Genome Integrity and Fertility Across Species.
Dev Cell
2020
31883965
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.
Cell Chem Biol
2020
32512502
An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.
Neoplasia
2020
31088835
Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas.
Cancer Res
2019
29258679
Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.
Eur Urol
2018
30217566
Targeting the turnover of oncoproteins as a new avenue for therapeutics development in castration-resistant prostate cancer.
Cancer Lett
2018
30420515
PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice.
Proc Natl Acad Sci U S A
2018
29749794
Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells.
Radiat Res
2018
29507699
Grade progression in urothelial carcinoma can occur with high or low mutational homology: a first-step toward tumor-specific care in initial low-grade bladder cancer.
Oncotarget
2018
29108672
FoxA transcription factor Fork head maintains the intestinal stem/progenitor cell identities in Drosophila.
Dev Biol
2018
28538184
Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.
Cell Rep
2017
28455392
Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.
Cancer Discov
2017
28122245
Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.
Cell Rep
2017
28263985
Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.
PLoS Genet
2017
29264534
Identification of the Underlying Androgen Receptor Defect in the Dallas Reifenstein Family.
J Endocr Soc
2017
27425409
HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.
Mol Cell
2016
28881577
A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas.
Oncotarget
2016
27626314
The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.
Oncotarget
2016
25043300
DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1.
Oncogene
2015
26484581
Minireview: Familiar Faces in Unfamiliar Places: The Emerging Role of Nuclear Receptors in Lung Cancer.
Mol Endocrinol
2015
26456834
Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin.
Cell Rep
2015
27308443
Harnessing the nuclear receptor PPARγ to inhibit the growth of lung adenocarcinoma by rewiring metabolic circuitries.
Mol Cell Oncol
2015
25722209
TCF4 Triplet Repeat Expansion and Nuclear RNA Foci in Fuchs' Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci
2015
24625679
Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells.
PLoS Genet
2014
26484153
An integrated functional genomic analysis identifies the antitumorigenic mechanism of action for PPARγ in lung cancer cells.
Genom Data
2014
25264247
Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.
Cell Metab
2014
24591637
Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.
Proc Natl Acad Sci U S A
2014
23375374
A comprehensive nuclear receptor network for breast cancer cells.
Cell Rep
2013
23685356
HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.
EMBO J
2013
23213231
Neuregulin 1-HER axis as a key mediator of hyperglycemic memory effects in breast cancer.
Proc Natl Acad Sci U S A
2012
22102826
Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness.
PLoS Genet
2011
21060808
Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.
PLoS Genet
2010
19563758
Genomic antagonism between retinoic acid and estrogen signaling in breast cancer.
Cell
2009
19345177
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Cell Stem Cell
2009
19427217
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.
Curr Biol
2009
19387489
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.
EMBO J
2009
18391959
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.
Nat Methods
2008
18635956
Systems biology of mammalian cell division.
Cell Cycle
2008
18207742
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.
Curr Biol
2008
1 - 50 of 67
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University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
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Kevin P White
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Sujun Hua
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Chao Xing
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University of Texas Southwestern Medical Center
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2
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Andrej Shevchenko
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