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Author Details
Full Name
Thomas M Kristie
Affiliation
National Institute of Allergy and Infectious Diseases
ORCID
Career Start Year
1984
Papers
54
H Index
32
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36692302
Deletion of the Transcriptional Coactivator HCF-1 <i>In Vivo</i> Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation.
mBio
2023
37886542
Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection.
bioRxiv
2023
35545036
A TRUSTED targeted mass spectrometry assay for pan-herpesvirus protein detection.
Cell Rep
2022
33271120
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
Immunity
2021
32518191
Inhibition of the Super Elongation Complex Suppresses Herpes Simplex Virus Immediate Early Gene Expression, Lytic Infection, and Reactivation from Latency.
mBio
2020
29594155
Effect of a Histone Demethylase Inhibitor on Equine Herpesvirus-1 Activity In Vitro.
Front Vet Sci
2018
29899098
The Cellular Coactivator HCF-1 Is Required for Glucocorticoid Receptor-Mediated Transcription of Bovine Herpesvirus 1 Immediate Early Genes.
J Virol
2018
29358051
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.
Cell
2018
28811345
Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens.
mBio
2017
28407486
Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency.
Cell Host Microbe
2017
26884430
Chromatin Modulation of Herpesvirus Lytic Gene Expression: Managing Nucleosome Density and Heterochromatic Histone Modifications.
mBio
2016
25702087
Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies.
Virology
2015
26651941
Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation.
Cell Host Microbe
2015
24418545
Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging.
Virology
2014
25473037
Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.
Sci Transl Med
2014
25367271
Analysis of HSV Viral Reactivation in Explants of Sensory Neurons.
Curr Protoc Microbiol
2014
25367270
Quantitative Analysis of HSV Gene Expression during Lytic Infection.
Curr Protoc Microbiol
2014
24425734
Epigenetic repression of herpes simplex virus infection by the nucleosome remodeler CHD3.
mBio
2014
23303604
Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency.
Sci Transl Med
2013
23698399
The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection.
Viruses
2013
23386436
A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency.
mBio
2013
23217624
Snapshots: chromatin control of viral infection.
Virology
2013
23253311
The rise of epigenetic targets for the development of novel antivirals.
Expert Rev Anti Infect Ther
2012
21285374
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.
Proc Natl Acad Sci U S A
2011
19682612
Control of alpha-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities.
Biochim Biophys Acta
2010
20133788
Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components.
Proc Natl Acad Sci U S A
2010
20200153
The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias.
J Biol Chem
2010
19570863
Recruitment of the transcriptional coactivator HCF-1 to viral immediate-early promoters during initiation of reactivation from latency of herpes simplex virus type 1.
J Virol
2009
19855399
Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency.
Nat Med
2009
18667495
Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons.
J Virol
2008
17578910
The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection.
Proc Natl Acad Sci U S A
2007
16624878
Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.
Proc Natl Acad Sci U S A
2006
15522876
Combinatorial transcription of herpes simplex virus and varicella zoster virus immediate early genes is strictly determined by the cellular coactivator HCF-1.
J Biol Chem
2005
14745036
Herpes simplex virus infections are arrested in Oct-1-deficient cells.
Proc Natl Acad Sci U S A
2004
15190068
A protein sequestering system reveals control of cellular programs by the transcriptional coactivator HCF-1.
J Biol Chem
2004
11559424
Rapid genetic selection of inhibitor-resistant protease mutants: clinically relevant and novel mutants of the HIV protease.
AIDS Res Hum Retroviruses
2001
10675337
The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP.
EMBO J
2000
10920196
Autocatalytic proteolysis of the transcription factor-coactivator C1 (HCF): a potential role for proteolytic regulation of coactivator function.
Proc Natl Acad Sci U S A
2000
9990006
Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency.
Proc Natl Acad Sci U S A
1999
9501175
A genetic screen for the isolation and characterization of site-specific proteases.
Proc Natl Acad Sci U S A
1998
9334261
The mouse homologue of the human transcription factor C1 (host cell factor). Conservation of forms and function.
J Biol Chem
1997
7876203
The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides.
J Biol Chem
1995
8454622
Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16).
J Biol Chem
1993
1358755
Recognition of the surface of a homeo domain protein.
Genes Dev
1992
1980658
Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.
Genes Dev
1990
2556266
The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.
EMBO J
1989
2831377
Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1.
J Virol
1988
2852507
The trans-activation of herpes simplex virus gene expression: comparison of two factors and their cis sites.
Biochimie
1988
2832940
The DNA-binding properties of the major regulatory protein alpha 4 of herpes simplex viruses.
Science
1988
2823252
Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins.
Proc Natl Acad Sci U S A
1987
1 - 50 of 54
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