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Author Details

Thomas M Kristie
National Institute of Allergy and Infectious Diseases
1984
54
32
PMIDPaper TitleJournal TitlePublished Year
36692302Deletion of the Transcriptional Coactivator HCF-1 <i>In Vivo</i> Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation.mBio2023
37886542Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection.bioRxiv2023
35545036A TRUSTED targeted mass spectrometry assay for pan-herpesvirus protein detection.Cell Rep2022
33271120Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.Immunity2021
32518191Inhibition of the Super Elongation Complex Suppresses Herpes Simplex Virus Immediate Early Gene Expression, Lytic Infection, and Reactivation from Latency.mBio2020
29594155Effect of a Histone Demethylase Inhibitor on Equine Herpesvirus-1 Activity In Vitro.Front Vet Sci2018
29899098The Cellular Coactivator HCF-1 Is Required for Glucocorticoid Receptor-Mediated Transcription of Bovine Herpesvirus 1 Immediate Early Genes.J Virol2018
29358051Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.Cell2018
28811345Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens.mBio2017
28407486Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency.Cell Host Microbe2017
26884430Chromatin Modulation of Herpesvirus Lytic Gene Expression: Managing Nucleosome Density and Heterochromatic Histone Modifications.mBio2016
25702087Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies.Virology2015
26651941Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation.Cell Host Microbe2015
24418545Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging.Virology2014
25473037Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.Sci Transl Med2014
25367271Analysis of HSV Viral Reactivation in Explants of Sensory Neurons.Curr Protoc Microbiol2014
25367270Quantitative Analysis of HSV Gene Expression during Lytic Infection.Curr Protoc Microbiol2014
24425734Epigenetic repression of herpes simplex virus infection by the nucleosome remodeler CHD3.mBio2014
23303604Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency.Sci Transl Med2013
23698399The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection.Viruses2013
23386436A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency.mBio2013
23217624Snapshots: chromatin control of viral infection.Virology2013
23253311The rise of epigenetic targets for the development of novel antivirals.Expert Rev Anti Infect Ther2012
21285374Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.Proc Natl Acad Sci U S A2011
19682612Control of alpha-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities.Biochim Biophys Acta2010
20133788Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components.Proc Natl Acad Sci U S A2010
20200153The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias.J Biol Chem2010
19570863Recruitment of the transcriptional coactivator HCF-1 to viral immediate-early promoters during initiation of reactivation from latency of herpes simplex virus type 1.J Virol2009
19855399Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency.Nat Med2009
18667495Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons.J Virol2008
17578910The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection.Proc Natl Acad Sci U S A2007
16624878Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.Proc Natl Acad Sci U S A2006
15522876Combinatorial transcription of herpes simplex virus and varicella zoster virus immediate early genes is strictly determined by the cellular coactivator HCF-1.J Biol Chem2005
14745036Herpes simplex virus infections are arrested in Oct-1-deficient cells.Proc Natl Acad Sci U S A2004
15190068A protein sequestering system reveals control of cellular programs by the transcriptional coactivator HCF-1.J Biol Chem2004
11559424Rapid genetic selection of inhibitor-resistant protease mutants: clinically relevant and novel mutants of the HIV protease.AIDS Res Hum Retroviruses2001
10675337The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP.EMBO J2000
10920196Autocatalytic proteolysis of the transcription factor-coactivator C1 (HCF): a potential role for proteolytic regulation of coactivator function.Proc Natl Acad Sci U S A2000
9990006Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency.Proc Natl Acad Sci U S A1999
9501175A genetic screen for the isolation and characterization of site-specific proteases.Proc Natl Acad Sci U S A1998
9334261The mouse homologue of the human transcription factor C1 (host cell factor). Conservation of forms and function.J Biol Chem1997
7876203The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides.J Biol Chem1995
8454622Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16).J Biol Chem1993
1358755Recognition of the surface of a homeo domain protein.Genes Dev1992
1980658Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.Genes Dev1990
2556266The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.EMBO J1989
2831377Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1.J Virol1988
2852507The trans-activation of herpes simplex virus gene expression: comparison of two factors and their cis sites.Biochimie1988
2832940The DNA-binding properties of the major regulatory protein alpha 4 of herpes simplex viruses.Science1988
2823252Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins.Proc Natl Acad Sci U S A1987
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Collaborators

National Institute of Allergy and Infectious Diseases
Co-authored papers 13
Princeton University
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
University of Miami Miller School of Medicine
Co-authored papers 1
National Institute of Allergy and Infectious Diseases
Co-authored papers 1
National Cancer Institute, National Institutes of Health (NIH)
Co-authored papers 1
Louisiana State University
Co-authored papers 1
Cedars-Sinai Medical Center, USA F. Widjaja Inflammatory Bowel Disease Institute
Co-authored papers 1
University of North Carolina
Co-authored papers 1
Genentech Inc.
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
Co-authored papers 1
National Institute of Arthritis, National Institutes of Health
Co-authored papers 1
Van Andel Institute
Co-authored papers 1
Broad Institute
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
National Institute of Allergy and Infectious Diseases
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
National Center for Advancing Translational Sciences
Co-authored papers 1
National Institute of Allergy and Infectious Diseases
Co-authored papers 1
University Hospital Erlangen, Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU)
Co-authored papers 1
University Hospital Southampton
Co-authored papers 1
Gladstone Institute of Virology
Co-authored papers 1
National Institute of Allergy and Infectious Diseases.
Co-authored papers 1
National Institute of Allergy and Infectious Diseases
Co-authored papers 1
Feinberg School of Medicine, Northwestern University
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1