Skip to Main Content

Author Details

Raymond J Monnat
University of Washington School of Medicine
1978
121
48
PMIDPaper TitleJournal TitlePublished Year
36912284Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource.Int J Cancer2023
37398090Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy.bioRxiv2023
36609876In Memory of George M. Martin.J Gerontol A Biol Sci Med Sci2023
35045296A functional module states framework reveals transcriptional states for drug and target prediction.Cell Rep2022
34968384Unsupervised discovery of dynamic cell phenotypic states from transmitted light movies.PLoS Comput Biol2021
32270149A microfluidic platform for functional testing of cancer drugs on intact tumor slices.Lab Chip2020
32500953High-throughput, microscope-based sorting to dissect cellular heterogeneity.Mol Syst Biol2020
32472073Tumour predisposition and cancer syndromes as models to study gene-environment interactions.Nat Rev Cancer2020
30793977New Human Chromosomal Sites with "Safe Harbor" Potential for Targeted Transgene Insertion.Hum Gene Ther2019
29146545Werner syndrome (WRN) gene variants and their association with altered function and age-associated diseases.Ageing Res Rev2018
30389308An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity.DNA Repair (Amst)2018
29617664Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.Cell Rep2018
26993153Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions.Ageing Res Rev2017
28276523Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype.Sci Rep2017
27859906Human RECQ Helicase Pathogenic Variants, Population Variation and "Missing" Diseases.Hum Mutat2017
26984941The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.Hum Mol Genet2016
30407401Development of a Whole Blood Paper-Based Device for Phenylalanine Detection in the Context of PKU Therapy Monitoring.Micromachines (Basel)2016
27672210Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest.J Biol Chem2016
27756748Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice.Blood2016
27121793WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy.Clin Cancer Res2016
27559010Werner syndrome through the lens of tissue and tumour genomics.Sci Rep2016
25427275Conversion of a laboratory-based test for phenylalanine detection to a simple paper-based format and implications for PKU screening in low-resource settings.Analyst2015
26397803Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin: Metabolic Tools for Enhanced Algal Fitness in the Prominent Order Prymnesiales (Haptophyceae).PLoS Genet2015
27158641Microwell arrays reveal cellular heterogeneity during the clonal expansion of transformed human cells.Technology (Singap World Sci)2015
25810110"...Rewritten in the skin": clues to skin biology and aging from inherited disease.J Invest Dermatol2015
23386316Diabetes mellitus and cancer in Werner syndrome.Acta Diabetol2014
25275698Parallel microfluidic chemosensitivity testing on individual slice cultures.Lab Chip2014
25310185MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial.PLoS One2014
25034814The mitochondrial and chloroplast genomes of the haptophyte Chrysochromulina tobin contain unique repeat structures and gene profiles.BMC Genomics2014
25104853Global and disease-associated genetic variation in the human Fanconi anemia gene family.Hum Mol Genet2014
24859205CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.Gastroenterology2014
24958861Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs.Proc Natl Acad Sci U S A2014
24510271Identification and analysis of genomic homing endonuclease target sites.Methods Mol Biol2014
24510267Homing endonuclease target site specificity defined by sequential enrichment and next-generation sequencing of highly complex target site libraries.Methods Mol Biol2014
24510266Quantifying the information content of homing endonuclease target sites by single base pair profiling.Methods Mol Biol2014
23253856Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.DNA Repair (Amst)2013
23908689Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.Transl Oncol2013
23684799PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks.DNA Repair (Amst)2013
23671119Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation.Proc Natl Acad Sci U S A2013
23713831Rapid assessment of RNAi-mediated protein depletion by selected reaction monitoring mass spectrometry.J Proteome Res2013
23396353Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.Nat Struct Mol Biol2013
23573208Spectrum and risk of neoplasia in Werner syndrome: a systematic review.PLoS One2013
22121229Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.Nucleic Acids Res2012
22570476Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication.J Biol Chem2012
21508956A synthetic homing endonuclease-based gene drive system in the human malaria mosquito.Nature2011
21288879Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering.Nucleic Acids Res2011
20065033Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation.Mol Cell Biol2010
20934517Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology.Semin Cancer Biol2010
20663905The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage.Cancer Res2010
19896421Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase.DNA Repair (Amst)2010
  • 1 - 50 of 121

Recommended Authors

Joanna I Loizou
Center for Cancer Research, Comprehensive Cancer Centre, Medical University of Vienna
Career Start Year 2002
Number of shared co-authors 0
Yassmine Akkari
Association for Molecular Pathology
Career Start Year 1999
Number of shared co-authors 1
Sandra Burkett
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 1
Ping Liang
College of Chemistry and Chemical Engineering, Hunan University
Career Start Year 1995
Number of shared co-authors 1
Alexei Protopopov
The University of MD Anderson Cancer Center
Career Start Year 1995
Number of shared co-authors 13
Glenn S Cowley
Broad Institute of Harvard and MIT
Career Start Year 1990
Number of shared co-authors 1
Richard A Gibbs
Baylor College of Medicine
Career Start Year 1987
Number of shared co-authors 18
Robert W Sobol
University of South Alabama
Career Start Year 1987
Number of shared co-authors 0
Alison A Bertuch
Baylor College of Medicine
Career Start Year 1987
Number of shared co-authors 0
Michael R Stratton
Wellcome Sanger Institute
Career Start Year 1987
Number of shared co-authors 8
Eivind Hovig
Center for Bioinformatics, University of Oslo
Career Start Year 1987
Number of shared co-authors 2
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Career Start Year 1987
Number of shared co-authors 0
John D McPherson
Ontario Institute for Cancer Research
Career Start Year 1986
Number of shared co-authors 4
Ralf Kittler
McDermott Center for Human Growth and Development.
Career Start Year 1984
Number of shared co-authors 1
David N Cooper
Institute of Medical Genetics, Cardiff University
Career Start Year 1983
Number of shared co-authors 1
Richard K Wilson
The Ohio State University
Career Start Year 1983
Number of shared co-authors 10
Michael F Christman
Coriell Institute for Medical Research
Career Start Year 1982
Number of shared co-authors 0
Ashok R Venkitaraman
University of Cambridge, Hutchison Research Centre
Career Start Year 1982
Number of shared co-authors 1
Stephen J Elledge
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Career Start Year 1982
Number of shared co-authors 7
Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
Career Start Year 1982
Number of shared co-authors 1
Peter K Rogan
CytoGnomix Inc.
Career Start Year 1981
Number of shared co-authors 0
David J Adams
Wellcome Sanger Institute
Career Start Year 1980
Number of shared co-authors 4
Richard M Myers
HudsonAlpha Institute for Biotechnology
Career Start Year 1980
Number of shared co-authors 4
Thomas W Glover
University of Michigan ann arbor
Career Start Year 1978
Number of shared co-authors 2
Robert L Nussbaum
Invitae Corporation
Career Start Year 1976
Number of shared co-authors 5
Norma Neff
Stanford University
Career Start Year 1974
Number of shared co-authors 0
Philip Hieter
University of British Columbia
Career Start Year 1974
Number of shared co-authors 4
Raju Kucherlapati
Harvard Medical School
Career Start Year 1973
Number of shared co-authors 19
Albert de la Chapelle
The Ohio State University Comprehensive Cancer Center
Career Start Year 1961
Number of shared co-authors 3
Thomas E Wilson
University of Michigan ann arbor
Career Start Year 1955
Number of shared co-authors 0

Collaborators

David Baker
University of Washington
Co-authored papers 4
William M Grady
. Fred Hutchinson Cancer Center
Co-authored papers 4
Peter S Rabinovitch
Co-authored papers 4
Ilya Shmulevich
Institute for Systems Biology
Co-authored papers 2
Joshua M Akey
Princeton University
Co-authored papers 2
Nyasha Chambwe
Institute of Molecular Medicine, Feinstein Institutes for Medical Research
Co-authored papers 2
Ana I Robles
Co-authored papers 2
Theo A Knijnenburg
Allen Institute for Cell Science
Co-authored papers 2
Monnie McGee
Southern Methodist University
Co-authored papers 2
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Agata Smogorzewska
Instituto de Investigacion Sanitaria Hospital 12 de Octubre (imas12)
Co-authored papers 1
Mostafa Karimi
Texas A&M University, College Station
Co-authored papers 1
Pora Kim
The University of Texas Health Science Center at Houston
Co-authored papers 1
Eve Shinbrot
Baylor College of Medicine
Co-authored papers 1
Josephine C Dorsman
Cancer Center Amsterdam
Co-authored papers 1
Lei Li
Zhenzhou University Cancer Center
Co-authored papers 1
Bin Feng
The First Affiliated Hospital of Jinan University
Co-authored papers 1
Colin C Pritchard
University of Washington, USA Brotman Baty Institute for Precision Medicine
Co-authored papers 1
Jianfang Liu
Peking University Third Hospital
Co-authored papers 1
David C Schwartz
University of Wisconsin-Madison
Co-authored papers 1
Michael J MacCoss
University of Washington
Co-authored papers 1
Denise M Wolf
University of California San Francisco
Co-authored papers 1
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 1
David L Gibbs
Institute for Systems Biology
Co-authored papers 1
Jeffrey R Whiteaker
Co-authored papers 1
Heidi L Kenerson
University of Washington
Co-authored papers 1
Gerrit A Meijer
The Netherlands Cancer Institute
Co-authored papers 1
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 1
Casey S Greene
Co-authored papers 1
Trisha N Davis
University of Washington
Co-authored papers 1
Release 1.2