Author details

Full Name

Jake Y Chen

Affiliation

ORCID

Career Start Year

2003

Papers

159

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37100826	Analysis of cardiac single-cell RNA-sequencing data can be improved by the use of artificial-intelligence-based tools.	Sci Rep	2023
37928259	A novel lncRNA-mediated epigenetic regulatory mechanism in periodontitis.	Int J Biol Sci	2023
37092468	AdipoAI suppresses osteoclastogenesis by activating AdipoR1/APPL1: An in vivo experimental study in diabetes-associated peri-implantitis.	Clin Oral Implants Res	2023
37143319	The adiponectin receptor agonist AdipoAI attenuates periodontitis in diabetic rats by inhibiting gingival fibroblast-induced macrophage migration.	Br J Pharmacol	2023
36703959	Construction of ceRNA and m6A-related lncRNA networks associated with anti-inflammation of AdipoAI.	Front Immunol	2023
36873496	AdipoRon accelerates bone repair of calvarial defect in diet-induced obesity mice.	Heliyon	2023
36803800	How cancer hijacks the body's homeostasis through the neuroendocrine system.	Trends Neurosci	2023
35263568	A nonredundant role for TÂ cell-derived interleukin 22 in antibacterial defense of colonic crypts.	Immunity	2022
35758816	DEMA: a distance-bounded energy-field minimization algorithm to model and layout biomolecular networks with quantitative features.	Bioinformatics	2022
35813949	The Periodontal Pathogen <i>Fusobacterium nucleatum</i> Exacerbates Alzheimer's Pathogenesis <i>via</i> Specific Pathways.	Front Aging Neurosci	2022
35495152	PAGER Web APP: An Interactive, Online Gene Set and Network Interpretation Tool for Functional Genomics.	Front Genet	2022
35666813	Single Nucleus Transcriptomics: Apical Resection in Newborn Pigs Extends the Time Window of Cardiomyocyte Proliferation and Myocardial Regeneration.	Circulation	2022
36407327	WINNER: A network biology tool for biomolecular characterization and prioritization.	Front Big Data	2022
36317800	Neuroendocrine signaling in the skin with a special focus on the epidermal neuropeptides.	Am J Physiol Cell Physiol	2022
35852875	An in vivo model of glioblastoma radiation resistance identifies long noncoding RNAs and targetable kinases.	JCI Insight	2022
34984683	A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes-associated periodontitis by enhancing autophagy in osteoclasts.	J Periodontal Res	2022
35128393	Editorial: Artificial Intelligence for Precision Medicine.	Front Artif Intell	2022
31180898	Scalable De Novo Genome Assembly Using a Pregel-Like Graph-Parallel System.	IEEE/ACM Trans Comput Biol Bioinform	2021
34120146	Metabolic alterations mediated by STAT3 promotes drug persistence in CML.	Leukemia	2021
33850196	Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs).	Sci Rep	2021
33627109	Linking clinotypes to phenotypes and genotypes from laboratory test results in comprehensive physical exams.	BMC Med Inform Decis Mak	2021
34273868	Osteogenic effects of microRNA-335-5p/lipidoid nanoparticles coated on titanium surface.	Arch Oral Biol	2021
34251623	Biological Network Mining.	Methods Mol Biol	2021
34191125	6-Shogaol promotes bone resorption and accelerates orthodontic tooth movement through the JNK-NFATc1 signaling axis.	J Bone Miner Metab	2021
32986862	Identification and characterization of a novel adiponectin receptor agonist adipo anti-inflammation agonist and its anti-inflammatory effects in vitro and in vivo.	Br J Pharmacol	2021
33245774	PAGER-CoV: a comprehensive collection of pathways, annotated gene-lists and gene signatures for coronavirus disease studies.	Nucleic Acids Res	2021
32572964	Irisin deficiency disturbs bone metabolism.	J Cell Physiol	2021
34870191	Corrigendum: Statistical Enrichment Analysis of Samples: A General-Purpose Tool to Annotate Metadata Neighborhoods of Biological Samples.	Front Big Data	2021
34901846	Editorial: AI-Enabled Data Science for COVID-19.	Front Big Data	2021
34958962	Polar Gini Curve: A Technique to Discover Gene Expression Spatial Patterns from Single-cell RNA-seq Data.	Genomics Proteomics Bioinformatics	2021
34604741	Statistical Enrichment Analysis of Samples: A General-Purpose Tool to Annotate Metadata Neighborhoods of Biological Samples.	Front Big Data	2021
34650969	Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis.	Front Cell Dev Biol	2021
31541471	Potential roles of miR-335-5p on pathogenesis of experimental periodontitis.	J Periodontal Res	2020
31838062	AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes.	Exp Cell Res	2020
32039707	Correction to: Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection.	BMC Infect Dis	2020
32703184	Polyvalent therapeutic vaccine for type 2 diabetes mellitus: Immunoinformatics approach to study co-stimulation of cytokines and GLUT1 receptors.	BMC Mol Cell Biol	2020
32730272	Identifying the key regulators that promote cell-cycle activity in the hearts of early neonatal pigs after myocardial injury.	PLoS One	2020
32510973	Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis.	Am J Physiol Cell Physiol	2020
32554431	IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice.	J Immunol	2020
30993080	A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia.	J Biol Res (Thessalon)	2019
31822287	Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection.	BMC Infect Dis	2019
30479003	Central adiponectin induces trabecular bone mass partly through epigenetic downregulation of cannabinoid receptor CB1.	J Cell Physiol	2019
30626266	An Adiponectin Receptor Agonist Reduces Type 2 Diabetic Periodontitis.	J Dent Res	2019
30813883	Gsslasso Cox: a Bayesian hierarchical model for predicting survival and detecting associated genes by incorporating pathway information.	BMC Bioinformatics	2019
31406955	Graft-Versus-Host Disease-Free Antitumoral Signature After Allogeneic Donor Lymphocyte Injection Identified by Proteomics and Systems Biology.	JCO Precis Oncol	2019
31114876	BEERE: a web server for biomedical entity expansion, ranking and explorations.	Nucleic Acids Res	2019
29593668	Simulation Study of cDNA Dataset to Investigate Possible Association of Differentially Expressed Genes of Human THP1-Monocytic Cells in Cancer Progression Affected by Bacterial Shiga Toxins.	Front Microbiol	2018
30030418	Regenerative Potential of Neonatal Porcine Hearts.	Circulation	2018
29886386	A novel Lipidoid-MicroRNA formulation promotes calvarial bone regeneration.	Biomaterials	2018
30040650	"Super Gene Set" Causal Relationship Discovery from Functional Genomics Data.	IEEE/ACM Trans Comput Biol Bioinform	2018