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Author Details
Full Name
Denise C Connolly
Affiliation
Fox Chase Cancer Center
ORCID
Career Start Year
1993
Papers
70
H Index
33
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37291133
Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles.
Nat Commun
2023
35467979
Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis.
Proc Natl Acad Sci U S A
2022
35804849
Development of a Multiprotein Classifier for the Detection of Early Stage Ovarian Cancer.
Cancers (Basel)
2022
34145035
CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.
Cancer Res
2021
34235374
Cholesterol and CDON Regulate Sonic Hedgehog Release from Pancreatic Cancer Cells.
J Pancreat Cancer
2021
32311117
Fluorescence and Multiphoton Imaging for Tissue Characterization of a Model of Postmenopausal Ovarian Cancer.
Lasers Surg Med
2020
32071169
Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.
Sci Signal
2020
30591091
Comparison of Reproductive Function in Female TgMISIIR-TAg Transgenic and Wildtype C57BL/6 Mice.
Comp Med
2019
31581233
RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.
PLoS One
2019
31571434
Quantification of multiphoton and fluorescence images of reproductive tissues from a mouse ovarian cancer model shows promise for early disease detection.
J Biomed Opt
2019
31308489
Rgnef promotes ovarian tumor progression and confers protection from oxidative stress.
Oncogene
2019
31478830
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Elife
2019
30929564
Targeted blockade of HSP90 impairs DNA-damage response proteins and increases the sensitivity of ovarian carcinoma cells to PARP inhibition.
Cancer Biol Ther
2019
31131879
Lineage tracing suggests that ovarian endosalpingiosis does not result from escape of oviductal epithelium.
J Pathol
2019
29737910
In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers.
Cancer Biol Ther
2018
30333627
Functional genomic landscape of acute myeloid leukaemia.
Nature
2018
29773902
NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice.
Oncogene
2018
27435394
Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.
Clin Cancer Res
2017
27197267
The BRCA1-ο11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.
Cancer Res
2016
27452461
Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer.
Cell Rep
2016
25646015
Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.
Mol Cancer Ther
2015
26618181
Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II.
J Immunol Res
2015
23334327
Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion.
Oncogene
2014
24786638
Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer.
Gynecol Oncol
2014
23900136
Network analysis identifies an HSP90-central hub susceptible in ovarian cancer.
Clin Cancer Res
2013
21785464
Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death.
Oncogene
2012
23226093
Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization.
Neoplasia
2012
22787427
Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice.
Neoplasia
2012
22782891
Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors.
J Biol Chem
2012
21326182
Miscommunication involving 'standard care'. Response to protocol review scenario: specify all medications.
Lab Anim (NY)
2011
20422001
Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers.
PLoS One
2010
21178956
An orthotopic model of serous ovarian cancer in immunocompetent mice for in vivo tumor imaging and monitoring of tumor immune responses.
J Vis Exp
2010
20958993
Development of a syngeneic mouse model of epithelial ovarian cancer.
J Ovarian Res
2010
20563260
Strategies for high-resolution imaging of epithelial ovarian cancer by laparoscopic nonlinear microscopy.
Transl Oncol
2010
19172191
Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation.
PLoS One
2009
22294392
Xenograft and transgenic mouse models of epithelial ovarian cancer and non-invasive imaging modalities to monitor ovarian tumor growth in situ: applications in evaluating novel therapeutic agents.
Curr Protoc Pharmacol
2009
20634901
Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents.
Curr Protoc Pharmacol
2009
20046879
Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.
PLoS One
2009
19763445
Animal models of ovarian cancer.
Cancer Treat Res
2009
19738060
NEDD9 promotes oncogenic signaling in mammary tumor development.
Cancer Res
2009
18771701
alpha-Galactosylceramide enhances the protective and therapeutic effects of tumor cell based vaccines for ovarian tumors.
Vaccine
2008
17363557
RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.
Cancer Res
2007
17986851
Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer.
Cancer Biol Ther
2007
16533786
Recombinant human Mullerian inhibiting substance inhibits long-term growth of MIS type II receptor-directed transgenic mouse ovarian cancers in vivo.
Clin Cancer Res
2006
17088539
Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.
Proc Natl Acad Sci U S A
2006
16849428
Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness.
Proc Natl Acad Sci U S A
2006
16510568
Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.
Cancer Res
2006
15149858
Membrane localization of v-ErbB is required but not sufficient for ligand-independent transformation.
Exp Cell Res
2004
15382342
Pathology of Ovarian Neoplasms in Genetically Modified Mice.
Comp Med
2004
14749123
Focus on epithelial ovarian cancer.
Cancer Cell
2004
1 - 50 of 70
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3
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Oregon Health and Science University
Co-authored papers
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Jason D MacManiman
Knight Cancer Institute, Oregon Health and Science University
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Instituto de Salud Carlos III
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Oncode Institute, Netherlands Cancer Institute
Co-authored papers
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National Cancer Institute, National Institutes of Health
Co-authored papers
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Aurora S Blucher
Knight Cancer Institute, Oregon Health Sciences University
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Oregon Health & Science University
Co-authored papers
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Brian J Druker
Oregon Health & Science University
Co-authored papers
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Justin M Watts
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1
Pierrette Lo
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers
1
Aashis Thapa
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Russell T Burke
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