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Author Details

Denise C Connolly
Fox Chase Cancer Center
1993
70
33
PMIDPaper TitleJournal TitlePublished Year
37291133Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles.Nat Commun2023
35467979Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis.Proc Natl Acad Sci U S A2022
35804849Development of a Multiprotein Classifier for the Detection of Early Stage Ovarian Cancer.Cancers (Basel)2022
34145035CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.Cancer Res2021
34235374Cholesterol and CDON Regulate Sonic Hedgehog Release from Pancreatic Cancer Cells.J Pancreat Cancer2021
32311117Fluorescence and Multiphoton Imaging for Tissue Characterization of a Model of Postmenopausal Ovarian Cancer.Lasers Surg Med2020
32071169Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.Sci Signal2020
30591091Comparison of Reproductive Function in Female TgMISIIR-TAg Transgenic and Wildtype C57BL/6 Mice.Comp Med2019
31581233RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.PLoS One2019
31571434Quantification of multiphoton and fluorescence images of reproductive tissues from a mouse ovarian cancer model shows promise for early disease detection.J Biomed Opt2019
31308489Rgnef promotes ovarian tumor progression and confers protection from oxidative stress.Oncogene2019
31478830FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.Elife2019
30929564Targeted blockade of HSP90 impairs DNA-damage response proteins and increases the sensitivity of ovarian carcinoma cells to PARP inhibition.Cancer Biol Ther2019
31131879Lineage tracing suggests that ovarian endosalpingiosis does not result from escape of oviductal epithelium.J Pathol2019
29737910In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers.Cancer Biol Ther2018
30333627Functional genomic landscape of acute myeloid leukaemia.Nature2018
29773902NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice.Oncogene2018
27435394Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.Clin Cancer Res2017
27197267The BRCA1-ο11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.Cancer Res2016
27452461Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer.Cell Rep2016
25646015Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.Mol Cancer Ther2015
26618181Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II.J Immunol Res2015
23334327Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion.Oncogene2014
24786638Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer.Gynecol Oncol2014
23900136Network analysis identifies an HSP90-central hub susceptible in ovarian cancer.Clin Cancer Res2013
21785464Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death.Oncogene2012
23226093Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization.Neoplasia2012
22787427Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice.Neoplasia2012
22782891Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors.J Biol Chem2012
21326182Miscommunication involving 'standard care'. Response to protocol review scenario: specify all medications.Lab Anim (NY)2011
20422001Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers.PLoS One2010
21178956An orthotopic model of serous ovarian cancer in immunocompetent mice for in vivo tumor imaging and monitoring of tumor immune responses.J Vis Exp2010
20958993Development of a syngeneic mouse model of epithelial ovarian cancer.J Ovarian Res2010
20563260Strategies for high-resolution imaging of epithelial ovarian cancer by laparoscopic nonlinear microscopy.Transl Oncol2010
19172191Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation.PLoS One2009
22294392Xenograft and transgenic mouse models of epithelial ovarian cancer and non-invasive imaging modalities to monitor ovarian tumor growth in situ: applications in evaluating novel therapeutic agents.Curr Protoc Pharmacol2009
20634901Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents.Curr Protoc Pharmacol2009
20046879Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.PLoS One2009
19763445Animal models of ovarian cancer.Cancer Treat Res2009
19738060NEDD9 promotes oncogenic signaling in mammary tumor development.Cancer Res2009
18771701alpha-Galactosylceramide enhances the protective and therapeutic effects of tumor cell based vaccines for ovarian tumors.Vaccine2008
17363557RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.Cancer Res2007
17986851Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer.Cancer Biol Ther2007
16533786Recombinant human Mullerian inhibiting substance inhibits long-term growth of MIS type II receptor-directed transgenic mouse ovarian cancers in vivo.Clin Cancer Res2006
17088539Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.Proc Natl Acad Sci U S A2006
16849428Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness.Proc Natl Acad Sci U S A2006
16510568Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.Cancer Res2006
15149858Membrane localization of v-ErbB is required but not sufficient for ligand-independent transformation.Exp Cell Res2004
15382342Pathology of Ovarian Neoplasms in Genetically Modified Mice.Comp Med2004
14749123Focus on epithelial ovarian cancer.Cancer Cell2004
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Collaborators

Co-authored papers 5
Co-authored papers 3
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Fox Chase Cancer Center
Co-authored papers 3
Fox Chase Cancer Center
Co-authored papers 2
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Laufer Center for Physical and Quantitative Biology, Stony Brook University
Co-authored papers 2
Oregon Health and Science University
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Instituto de Salud Carlos III
Co-authored papers 1
Oncode Institute, Netherlands Cancer Institute
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National Cancer Institute, National Institutes of Health
Co-authored papers 1
Knight Cancer Institute, Oregon Health Sciences University
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
University of Miami, Sylvester Comprehensive Cancer Center
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Emory School of Medicine
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Morehouse School of Medicine
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University, Knight Cancer Institute
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
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Chinese University of Hong Kong
Co-authored papers 1