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Author Details
Full Name
Eyal Akiva
Affiliation
University of California san francisco
ORCID
Career Start Year
2006
Papers
24
H Index
16
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
32956445
Human SIRT1 Multispecificity Is Modulated by Active-Site Vicinity Substitutions during Natural Evolution.
Mol Biol Evol
2021
33674467
Parallel molecular mechanisms for enzyme temperature adaptation.
Science
2021
34437092
Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics.
Science
2021
31072492
Exploring the sequence, function, and evolutionary space of protein superfamilies using sequence similarity networks and phylogenetic reconstructions.
Methods Enzymol
2019
31074977
Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry
2019
29184004
A global view of structure-function relationships in the tautomerase superfamily.
J Biol Chem
2018
30052428
Revealing Unexplored Sequence-Function Space Using Sequence Similarity Networks.
Biochemistry
2018
30097089
Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.
Methods Enzymol
2018
27812939
Evaluating Functional Annotations of Enzymes Using the Gene Ontology.
Methods Mol Biol
2017
28365730
Biocuration in the structure-function linkage database: the anatomy of a superfamily.
Database (Oxford)
2017
28342985
Mast cells are directly activated by contact with cancer cells by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.
Cancer Lett
2017
29078300
Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily.
Proc Natl Acad Sci U S A
2017
28605775
Biocuration in the structure-function linkage database: the anatomy of a superfamily.
Database (Oxford)
2017
25654171
[FeFe]-hydrogenase maturation: insights into the role HydE plays in dithiomethylamine biosynthesis.
Biochemistry
2015
26496596
Evolutionary reprograming of protein-protein interaction specificity.
Cell
2015
24271399
The Structure-Function Linkage Database.
Nucleic Acids Res
2014
24980702
Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks.
Elife
2014
24756107
Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.
PLoS Biol
2014
22253583
A dynamic view of domain-motif interactions.
PLoS Comput Biol
2012
22927804
Prediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein design.
PLoS Comput Biol
2012
22190034
Global landscape of HIV-human protein complexes.
Nature
2011
20802208
Preferential use of protein domain pairs as interaction mediators: order and transitivity.
Bioinformatics
2010
18757736
Built-in loops allow versatility in domain-domain interactions: lessons from self-interacting domains.
Proc Natl Acad Sci U S A
2008
17184549
Evolutionary conservation of domain-domain interactions.
Genome Biol
2006
1 - 24 of 24
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