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Author Details

Julian C Knight
University of Oxford
1997
150
59
PMIDPaper TitleJournal TitlePublished Year
35092292Response to Letter to the Editor by Ish et al. entitled 'COVID-19 vaccine equity-the need of the hour'.QJM2023
37596262A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.Nat Commun2023
37388915Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis.Cell Genom2023
36760998Chromosome conformation capture approaches to investigate 3D genome architecture in Ankylosing Spondylitis.Front Genet2023
36353986COMBATdb: a database for the COVID-19 Multi-Omics Blood ATlas.Nucleic Acids Res2023
34446464Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia.Eur Respir J2022
35835762Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity.Nat Commun2022
35345417SARS-CoV-2-specific antibody and T-cell responses 1 year after infection in people recovered from COVID-19: a longitudinal cohort study.Lancet Microbe2022
35780481The suboptimal fibrinolytic response in COVID-19 is dictated by high PAI-1.J Thromb Haemost2022
35751107Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance.Genome Biol2022
35715504Redefining critical illness.Nat Med2022
35069677Disruption of c-MYC Binding and Chromosomal Looping Involving Genetic Variants Associated With Ankylosing Spondylitis Upstream of the <i>RUNX3</i> Promoter.Front Genet2022
34853448An immunodominant NP<sub>105-113</sub>-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.Nat Immunol2022
35196807Implementation and Extended Evaluation of the Euroimmun Anti-SARS-CoV-2 IgG Assay and Its Contribution to the United Kingdom's COVID-19 Public Health Response.Microbiol Spectr2022
34865168Why do breakthrough COVID-19 infections occur in the vaccinated?QJM2022
35192718Fine-Scale Genetic Structure in the United Arab Emirates Reflects Endogamous and Consanguineous Culture, Population History, and Geography.Mol Biol Evol2022
34843810Serum calprotectin is not an independent predictor of severe COVID-19 in ambulatory adult patients.J Infect2022
34751399Priority index: database of genetic targets in immune-mediated disease.Nucleic Acids Res2022
33277640Host genetics and infectious disease: new tools, insights and translational opportunities.Nat Rev Genet2021
33743891Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera.Cell2021
33852911Antibody evasion by the P.1 strain of SARS-CoV-2.Cell2021
33591001Sepsis Subclasses: A Framework for Development and Interpretation.Crit Care Med2021
33756110The antigenic anatomy of SARS-CoV-2 receptor binding domain.Cell2021
33730597Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera.Cell2021
33608581Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages.Sci Rep2021
33746983Transcriptomic Analysis of Inflammatory Cardiomyopathy Identifies Molecular Signatures of Disease and Informs <i>in silico</i> Prediction of a Network-Based Rationale for Therapy.Front Immunol2021
34859219Maternal immune activation downregulates schizophrenia genes in the foetal mouse brain.Brain Commun2021
34737427Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.Nat Genet2021
34687210Early childhood epilepsies: epidemiology, classification, aetiology, and socio-economic determinants.Brain2021
34475573Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.Nat Genet2021
34242578Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum.Cell2021
34343164Using de novo assembly to identify structural variation of eight complex immune system gene regions.PLoS Comput Biol2021
34238349Pre-existing asthma as a comorbidity does not modify cytokine responses and severity of COVID-19.Allergy Asthma Clin Immunol2021
34009545Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders.J Clin Immunol2021
34279044Genomic Insights into Myasthenia Gravis Identify Distinct Immunological Mechanisms in Early and Late Onset Disease.Ann Neurol2021
34226188Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid.Ann Rheum Dis2021
33369221Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis.Arthritis Rheumatol2021
33307546Genetic mechanisms of critical illness in COVID-19.Nature2021
31462703Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus.Genes Immun2020
32042196Peripheral CD8<sup>+</sup> T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma.Nat Med2020
32039044Assessment of an Antibody-in-Lymphocyte Supernatant Assay for the Etiological Diagnosis of Pneumococcal Pneumonia in Children.Front Cell Infect Microbiol2020
33087723Early-onset autoimmunity associated with SOCS1 haploinsufficiency.Nat Commun2020
32888494The Polygenic and Monogenic Basis of Blood Traits and Diseases.Cell2020
32577665Broad and strong memory CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.bioRxiv2020
32759223Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300.Proc Natl Acad Sci U S A2020
32501293Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease.JCI Insight2020
32348495Interferon-Induced Transmembrane Protein 3 Genetic Variant rs12252-C Associated With Disease Severity in Coronavirus Disease 2019.J Infect Dis2020
30365341Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial.Am J Respir Crit Care Med2019
31835999Use of gene expression studies to investigate the human immunological response to malaria infection.Malar J2019
31345272Implementation of a genomic medicine multi-disciplinary team approach for rare disease in the clinical setting: a prospective exome sequencing case series.Genome Med2019
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Collaborators

Hai Fang
University of Bristol
Co-authored papers 11
Vivek Naranbhai
Massachusetts General Hospital/Harvard Medical School
Co-authored papers 9
Bryan Paul Wordsworth
Co-authored papers 8
Anthony C Gordon
Imperial College London
Co-authored papers 7
Brendan J Keating
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 6
Lili Milani
Co-authored papers 6
David I Stuart
University of Oxford
Co-authored papers 6
Tõnu Esko
Co-authored papers 5
Anna Rautanen
Co-authored papers 5
Silva Kasela
Co-authored papers 5
Lude Franke
Co-authored papers 4
John Kenneth Baillie
Roslin Institute, University of Edinburgh
Co-authored papers 4
Uwe V??lker
University Medicine
Co-authored papers 4
Jenny C Taylor
University of Oxford
Co-authored papers 4
Anthony P Monaco
Monash University
Co-authored papers 4
Tom van der Poll
Center for Experimental and Molecular Medicine, University of Amsterdam
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John Taylor
Oxford University Hospitals NHS Foundation Trust, Churchill Hospital
Co-authored papers 4
Hugh Watkins
Co-authored papers 4
Mark A Williams
Harwell Science & Innovation Campus
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Hector R Wong
University of Cincinnati College of Medicine
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Oliver Stegle
Wellcome Sanger Institute
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Benjamin Tang
University of Sydney Nepean Clinical School, Nepean Hospital
Co-authored papers 3
Manu Shankar-Hari
King's College London
Co-authored papers 3
Markus Perola
Co-authored papers 3
Patrick F Bolton
Co-authored papers 3
Johannes Kettunen
Co-authored papers 3
Richard Holt
Oxford Brookes University
Co-authored papers 3
Bruce M Psaty
Co-authored papers 3
Hanieh Yaghootkar
Co-authored papers 3
Samuli Ripatti
Co-authored papers 3
Release 1.2