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Author Details

Kristel Kemper
Oncode Institute, The Netherlands Cancer Institute
2005
33
24
PMIDPaper TitleJournal TitlePublished Year
36271507Mechanistic and pharmacodynamic studies of DuoBody-CD3x5T4 in preclinical tumor models.Life Sci Alliance2022
33466732Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid Tumors.Cancers (Basel)2021
34230026Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.Clin Cancer Res2021
31160710Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.Nat Cell Biol2019
31270153<i>In Vivo</i> ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.Mol Cancer Ther2019
31521607High-Throughput Assessment of Kinome-wide Activation States.Cell Syst2019
29334371Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors.Nat Med2018
30286710XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.BMC Bioinformatics2018
29634951Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.Cancer Cell2018
29438700Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.Cancer Cell2018
29507054Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.Mol Syst Biol2018
28912576Interrogating open issues in cancer medicine with patient-derived xenografts.Nat Rev Cancer2017
28104906Interrogating open issues in cancer precision medicine with patient-derived xenografts.Nat Rev Cancer2017
28976960Cancer drug addiction is relayed by an ERK2-dependent phenotype switch.Nature2017
29092942PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.Cancer Res2017
26999069MITF: More Interesting Traits, Folks!Pigment Cell Melanoma Res2016
27320919BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.Cell Rep2016
25887352CopywriteR: DNA copy number detection from off-target sequence data.Genome Biol2015
26105199Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.EMBO Mol Med2015
25320006Phenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy.Cancer Res2014
25502142Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.Nat Commun2014
25456132Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition.Cell Rep2014
22223359Targeting colorectal cancer stem cells with inducible caspase-9.Apoptosis2012
22969042Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells.Stem Cells2012
22496204Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer.Clin Cancer Res2012
20068153The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation.Cancer Res2010
21311095Molecular identification and targeting of colorectal cancer stem cells.Oncotarget2010
20808829Mouse tissues express multiple splice variants of prominin-1.PLoS One2010
20418870Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.Nat Cell Biol2010
18281498Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer.Cancer Res2008
18765800Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.Proc Natl Acad Sci U S A2008
18259194Cancer stem cells--old concepts, new insights.Cell Death Differ2008
16327494Neoadjuvant selective COX-2 inhibition down-regulates important oncogenic pathways in patients with esophageal adenocarcinoma.Ann Surg2005
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Collaborators

Daniel S Peeper
Netherlands Cancer Institute
Co-authored papers 20
Oscar Krijgsman
The Netherlands Cancer Institute
Co-authored papers 11
Jan Paul Medema
Oncode Institute
Co-authored papers 9
Louis Vermeulen
Oncode Institute
Co-authored papers 6
Jos Jonkers
Oncode Institute, Netherlands Cancer Institute
Co-authored papers 5
David J Adams
Wellcome Sanger Institute
Co-authored papers 5
Annette T Byrne
Royal College of Surgeons in Ireland (RCSI)
Co-authored papers 3
Livio Trusolino
Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 3
Lodewyk F A Wessels
University Medical Centre Mannheim, University of Heidelberg
Co-authored papers 3
Enzo Medico
Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia (FPO) - IRCCS
Co-authored papers 3
Emilie Vinolo
CNRS URA 5
Co-authored papers 3
Alejandra Bruna
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 3
Oscar M Rueda
University of Cambridge
Co-authored papers 3
Els Hermans
Netherlands Cancer Institute
Co-authored papers 3
Ultan McDermott
Wellcome Sanger Institute
Co-authored papers 3
Fr??d??ric Amant
Netherlands Cancer Institute
Co-authored papers 3
Andrea Bertotti
Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 3
Hans Clevers
Princess Maxima Center for Pediatric Oncology
Co-authored papers 3
Carlos Caldas
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 3
Emile E Voest
The Netherlands Cancer Institute
Co-authored papers 2
Elisabetta Marangoni
Co-authored papers 2
Abdel G Elkahloun
National Human Genome Research Institute
Co-authored papers 2
Yardena Samuels
Weizmann Institute of Science
Co-authored papers 2
Theodore C Goldstein
Bakar Computational Health Sciences Institute, University of California san francisco
Co-authored papers 1
Johan Bostr??m
Karolinska Institutet
Co-authored papers 1
Andrew E Aplin
Thomas Jefferson University
Co-authored papers 1
Amanda L Christie
Dana-Farber Cancer Institute
Co-authored papers 1
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Jeremy Mason
European Molecular Biology Laboratory - European Bioinformatics Institute
Co-authored papers 1
Katherine L Nathanson
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Release 1.2