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Author Details

Hon S Leong
University of Toronto
2002
67
31
PMIDPaper TitleJournal TitlePublished Year
36671682Histological Characterization of Class I HLA Molecules in Whole Umbilical Cord Tissue Towards an Inexhaustible Graft Alternative for Reconstructive Surgery.Bioengineering (Basel)2023
34088927Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma.Sci Rep2021
33589770Clinical significance of STEAP1 extracellular vesicles in prostate cancer.Prostate Cancer Prostatic Dis2021
32314552Image-guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies.Wiley Interdiscip Rev Nanomed Nanobiotechnol2020
32707733The Emerging Role of Extracellular Vesicles in the Glioma Microenvironment: Biogenesis and Clinical Relevance.Cancers (Basel)2020
33010939Patient-derived xenografts in surgical oncology: A short research review.Surgery2020
30697731TBX3 promotes progression of pre-invasive breast cancer cells by inducing EMT and directly up-regulating SLUG.J Pathol2019
31803361Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion.Oncotarget2019
31327041A prospective feasibility study evaluating the role of multimodality imaging and liquid biopsy for response assessment in locally advanced rectal carcinoma.Abdom Radiol (NY)2019
31475741Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients.Prostate2019
30987640RSPO3 is a prognostic biomarker and mediator of invasiveness in prostate cancer.J Transl Med2019
30800217Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases.Oncotarget2019
30680751Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma.Prostate2019
30651600Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis.Oncogene2019
30647137The role of extracellular vesicles in cancer microenvironment and metastasis: myths and challenges.Biochem Soc Trans2019
29190494FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway.Neoplasia2018
30082495<i>Drosophila melanogaster</i> as a function-based high-throughput screening model for antinephrolithiasis agents in kidney stone patients.Dis Model Mech2018
30112749Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity.Thromb Haemost2018
30419054Lestaurtinib is a potent inhibitor of anaplastic thyroid cancer cell line models.PLoS One2018
29618619Prevalent Homozygous Deletions of Type I Interferon and Defensin Genes in Human Cancers Associate with Immunotherapy Resistance.Clin Cancer Res2018
29769644Translational models of prostate cancer bone metastasis.Nat Rev Urol2018
27889376The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells.Exp Cell Res2017
28306507Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells.Mol Cell2017
28322574Editorial Comment for Yoshino et al.: Image-Guided Research in the Clinic to Reduce Surgical Margins.J Endourol2017
28419078Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis.Br J Cancer2017
28937653Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells.Int J Mol Sci2017
29069723Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer.Oncotarget2017
28762517Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples.Prostate2017
28578396Neonicotinoid-induced pathogen susceptibility is mitigated by Lactobacillus plantarum immune stimulation in a Drosophila melanogaster model.Sci Rep2017
27101515Quantification of cancer cell extravasation in vivo.Nat Protoc2016
27756325Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells.Mol Cancer2016
27141054Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma.Mol Cell Biol2016
27553211The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer.BMC Cancer2016
27520820Probiotic Lactobacillus rhamnosus Reduces Organophosphate Pesticide Absorption and Toxicity to Drosophila melanogaster.Appl Environ Microbiol2016
26960793SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases.Mol Biol Cell2016
26771074Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis.Sci Rep2016
26814433Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry.Oncotarget2016
25613050CORRIGENDUM: Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway.Sci Rep2015
26544365[Not Available].Prog Urol2015
26068241Inhibition of endogenous hydrogen sulfide production in clear-cell renal cell carcinoma cell lines and xenografts restricts their growth, survival and angiogenic potential.Nitric Oxide2015
25964141Extracellular vesicles such as prostate cancer cell fragments as a fluid biopsy for prostate cancer.Prostate Cancer Prostatic Dis2015
25741641Evaluating the effectiveness of cancer drug sensitization in vitro and in vivo.J Vis Exp2015
24398519Hypoxia promotes tumor cell motility via RhoA and ROCK1 signaling pathways.Proc Natl Acad Sci U S A2014
25204426Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway.Sci Rep2014
24974076BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis.Mol Oncol2014
25176655Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.Cell Rep2014
24733940Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.Proc Natl Acad Sci U S A2014
24879294Cyclin A2, a novel regulator of EMT.Cell Mol Life Sci2014
23525242KISS1R induces invasiveness of estrogen receptor-negative human mammary epithelial and breast cancer cells.Endocrinology2013
24107191Re-examining the size/charge paradigm: differing in vivo characteristics of size- and charge-matched mesoporous silica nanoparticles.J Am Chem Soc2013
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Collaborators

Mayo Clinic
Co-authored papers 7
University of Western Ontario
Co-authored papers 3
University of California los angeles
Co-authored papers 3
Juravinski Cancer Centre
Co-authored papers 2
Medical College, Yan'an University
Co-authored papers 2
Western University, Lawson Health Research Institute
Co-authored papers 2
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 2
University of Illinois at Urbana-Champaign
Co-authored papers 2
University of Perugia
Co-authored papers 2
University of Western Ontario
Co-authored papers 2
College of Medicine, University of Saskatchewan
Co-authored papers 2
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 2
School of Public Policy at the University of Calgary
Co-authored papers 2
University of Western Ontario
Co-authored papers 2
Schulich School of Medicine & Dentistry, Western University, Victoria Hospital
Co-authored papers 2
Odette Cancer Centre, University of Toronto
Co-authored papers 2
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 2
University of Western Ontario
Co-authored papers 2
McMaster University
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Sunnybrook Research Institute
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Western University
Co-authored papers 1
CHU de Quebec-Universite Laval
Co-authored papers 1
Schulich School of Medicine and Dentistry, The University of Western Ontario
Co-authored papers 1
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 1
University of California Davis Health
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University Avenue R988
Co-authored papers 1
University of Toronto
Co-authored papers 1