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Author Details
Full Name
David Cowburn
Affiliation
Albert Einstein College of Medicine
ORCID
Career Start Year
1969
Papers
151
H Index
46
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37064528
Improving the Hole Picture: Towards a Consensus on the Mechanism of Nuclear Transport.
ArXiv
2023
37099395
Improving the hole picture: towards a consensus on the mechanism of nuclear transport.
Biochem Soc Trans
2023
35231399
Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo.
Cell Chem Biol
2022
35679349
A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice.
PLoS Pathog
2022
35528138
NMR Assignment through Linear Programming.
J Glob Optim
2022
36194550
A Conserved Histidine Residue Drives Extein Dependence in an Enhanced Atypically Split Intein.
J Am Chem Soc
2022
33980829
INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.
Nat Commun
2021
32696372
Analysis of Multivalent IDP Interactions: Stoichiometry, Affinity, and Local Concentration Effect Measurements.
Methods Mol Biol
2020
31199001
Phase separation in biology and disease-a symposium report.
Ann N Y Acad Sci
2019
29429880
Deciphering the "Fuzzy" Interaction of FG Nucleoporins and Transport Factors Using Small-Angle Neutron Scattering.
Structure
2018
30156841
An Atypical Mechanism of Split Intein Molecular Recognition and Folding.
J Am Chem Soc
2018
29374059
Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex.
J Biol Chem
2018
27714614
Segmental Isotopic Labeling of Proteins for NMR Study Using Intein Technology.
Methods Mol Biol
2017
28162953
Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Structure
2017
28151998
Effects of FGFR2 kinase activation loop dynamics on catalytic activity.
PLoS Comput Biol
2017
29263320
Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release.
Nat Commun
2017
28616711
Integrating NOE and RDC using sum-of-squares relaxation for protein structure determination.
J Biomol NMR
2017
28739907
A promiscuous split intein with expanded protein engineering applications.
Proc Natl Acad Sci U S A
2017
27815825
Domain interactions of C-terminal Src Kinase determined through NMR spectroscopy with segmental isotope labeling.
Protein Cell
2017
26854538
Design of a Split Intein with Exceptional Protein Splicing Activity.
J Am Chem Soc
2016
26655427
Anti-DNA antibody mediated catalysis is isotype dependent.
Mol Immunol
2016
26482679
A peptide mimic blocks the cross-reaction of anti-DNA antibodies with glomerular antigens.
Clin Exp Immunol
2016
27819029
Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.
Biophys Rep
2016
27091992
Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex.
Proc Natl Acad Sci U S A
2016
25749870
Erratum to: Correlation of chemical shifts predicted by molecular dynamics simulations for partially disordered proteins.
J Biomol NMR
2015
26371551
The molecular mechanism of nuclear transport revealed by atomic-scale measurements.
Elife
2015
26690112
Identification of Hydrophobic Interfaces in Protein-Ligand Complexes by Selective Saturation Transfer NMR Spectroscopy.
Molecules
2015
25634639
Controlling lipid micelle stability using oligonucleotide headgroups.
J Am Chem Soc
2015
24695731
Structural and dynamical features of inteins and implications on protein splicing.
J Biol Chem
2014
23506399
Extein residues play an intimate role in the rate-limiting step of protein trans-splicing.
J Am Chem Soc
2013
24236406
Naturally split inteins assemble through a "capture and collapse" mechanism.
J Am Chem Soc
2013
23911417
Global structures of IgG isotypes expressing identical variable regions.
Mol Immunol
2013
23871672
Cracking the molecular origin of intrinsic tyrosine kinase activity through analysis of pathogenic gain-of-function mutations.
Cell Rep
2013
23583913
Ligand-induced dynamic changes in extended PDZ domains from NHERF1.
J Mol Biol
2013
22167671
Expression and purification of Src-family kinases for solution NMR studies.
Methods Mol Biol
2012
24432187
Eigenvector synchronization, graph rigidity and the molecule problem.
Inf inference
2012
22930758
Variable region identical immunoglobulins differing in isotype express different paratopes.
J Biol Chem
2012
22592215
Abl kinase constructs expressed in bacteria: facilitation of structural and functional studies including segmental labeling by expressed protein ligation.
Mol Biosyst
2012
22244757
The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition.
Structure
2012
22170623
Novel structures of self-associating stapled peptides.
Biopolymers
2012
21067413
Are zinc-finger domains of protein kinase C dynamic structures that unfold by lipid or redox activation?
Antioxid Redox Signal
2011
21539734
Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain.
Retrovirology
2011
20042604
A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.
J Biol Chem
2010
20880835
Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.
Proc Natl Acad Sci U S A
2010
20951618
On the measurement of ¹âµN-{¹H} nuclear Overhauser effects. 2. Effects of the saturation scheme and water signal suppression.
J Magn Reson
2010
20495572
Branched intermediate formation stimulates peptide bond cleavage in protein splicing.
Nat Chem Biol
2010
20633361
Nuclear spin relaxation in isotropic and anisotropic media.
Prog Nucl Magn Reson Spectrosc
2010
20372977
Structural determination of biomolecular interfaces by nuclear magnetic resonance of proteins with reduced proton density.
J Biomol NMR
2010
19358609
Accurate sampling of high-frequency motions in proteins by steady-state (15)N-{(1)H} nuclear Overhauser effect measurements in the presence of cross-correlated relaxation.
J Am Chem Soc
2009
19632474
Segmental isotopic labeling of proteins for nuclear magnetic resonance.
Methods Enzymol
2009
1 - 50 of 151
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