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Author Details

Janet Rossant
The Hospital for Sick Children
1975
416
135
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37471320Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo.PLoS One2023
37563444Studying human embryo development with E-assembloids.Cell Res2023
37373413A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells.Int J Mol Sci2023
35077679Early human embryonic development: Blastocyst formation to gastrulation.Dev Cell2022
35736539Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons.Elife2022
35395176Diversifying stem cell debates: Including Muslim contexts and perspectives.Stem Cell Reports2022
35659873Anniversary reflections: ISSCR presidents on 20 years of progress.Cell Stem Cell2022
35385686Celebrating scientific excellence and global health impact: The 2022 Canada Gairdner Awards.Cell2022
36055191Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells.Cell Stem Cell2022
35042406Live imaging YAP signalling in mouse embryo development.Open Biol2022
33420491Evaluating totipotency using criteria of increasing stringency.Nat Cell Biol2021
33883273Fetal lung underdevelopment is rescued by administration of amniotic fluid stem cell extracellular vesicles in rodents.Sci Transl Med2021
33667412Opportunities and challenges with stem cell-based embryo models.Stem Cell Reports2021
34672948The exploration of pluripotency space: Charting cell state transitions in peri-implantation development.Cell Stem Cell2021
34210797Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor.Proc Natl Acad Sci U S A2021
34048692ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.Stem Cell Reports2021
34048690Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.Stem Cell Reports2021
32234520Canada Gairdner Awards 2020: A Tightly Woven Tapestry of Discovery.Cell2020
31951813Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells.Stem Cell Reports2020
31912993Efficient Generation of Large-Fragment Knock-In Mouse Models Using 2-Cell (2C)-Homologous Recombination (HR)-CRISPR.Curr Protoc Mouse Biol2020
29685812The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF.J Cyst Fibros2019
31233251Inhibition of Phosphoinositide-3-Kinase Signaling Promotes the Stem Cell State of Trophoblast.Stem Cells2019
31315026Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos.Dev Biol2019
31227724Conversion of human and mouse fibroblasts into lung-like epithelial cells.Sci Rep2019
311890912018 ISSCR Strategic Planning: Looking to the Future.Stem Cell Reports2019
30824615Preparation of Polymerase Chain Reaction Templates from Embryonic and Adult Mouse Tissue Samples.Cold Spring Harb Protoc2019
29066530Regulation of porcupine-dependent Wnt signaling is essential for uterine development and function.Reproduction2018
29889212Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos.Nat Biotechnol2018
30183407Genetic Control of Early Cell Lineages in the Mammalian Embryo.Annu Rev Genet2018
30045910Gene editing in human development: ethical concerns and practical applications.Development2018
29880675Exploring early human embryo development.Science2018
30542177Debate ethics of embryo models from stem cells.Nature2018
29378814Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions.Mol Syst Biol2018
29183906Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function.Biol Open2018
28061351New Insights into Early Human Development: Lessons for Stem Cell Derivation and Differentiation.Cell Stem Cell2017
28226240Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo.Elife2017
29036275Porcupine-dependent Wnt activity within the uterine epithelium is essential for fertility.Biol Reprod2017
28985523Human Embryo Editing: Opportunities and Importance of Transnational Cooperation.Cell Stem Cell2017
29214996The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation.Sci Rep2017
28649446Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia.NPJ Genom Med2017
28742026AIRE is a critical spindle-associated protein in embryonic stem cells.Elife2017
27965056Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs.Dev Biol2017
26969983Making the Mouse Blastocyst: Past, Present, and Future.Curr Top Dev Biol2016
26675727Corrigendum: Hallmarks of pluripotency.Nature2016
27618721Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay.Stem Cell Reports2016
27905428Stem cells and interspecies chimaeras.Nature2016
27144361Human embryology: Implantation barrier overcome.Nature2016
27256674Distinct mechanisms regulate Cdx2 expression in the blastocyst and in trophoblast stem cells.Sci Rep2016
27251772Flt1/VEGFR1 heterozygosity causes transient embryonic edema.Sci Rep2016
26862703What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast.Stem Cell Reports2016
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Collaborators

William L Stanford
Ottawa Hospital Research Institute
Co-authored papers 17
Ann M Flenniken
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 12
Wolfgang Wurst
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 10
Benoit G Bruneau
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
Co-authored papers 9
Tony Pawson
Co-authored papers 8
Jane E Aubin
University of Toronto
Co-authored papers 8
Ralph A Zirngibl
University of Toronto
Co-authored papers 8
George Q Daley
Boston Children's Hospital, Harvard Medical School
Co-authored papers 7
Derek van der Kooy
University of Toronto
Co-authored papers 7
William C Skarnes
Wellcome Trust Sanger Institute
Co-authored papers 6
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 6
Colin McKerlie
The Hospital for Sick Children
Co-authored papers 6
Insoo Hyun
Center for Bioethics, Harvard Medical School
Co-authored papers 5
Nicolas C Rivron
Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
Co-authored papers 5
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 5
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Timothy R Hughes
University of Toronto
Co-authored papers 4
Ronald D G McKay
Co-authored papers 4
Martin Hrab?? de Angelis
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 4
Brendan J Frey
University of Toronto
Co-authored papers 4
M A Surani
The Gurdon Institute
Co-authored papers 4
Lauryl M J Nutter
The Hospital for Sick Children
Co-authored papers 4
Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 4
Christine L Mummery
Leiden University Medical Center
Co-authored papers 4
Fran??ois Guillemot
the Francis Crick Institute
Co-authored papers 4
Robin Lovell-Badge
The Francis Crick Institute
Co-authored papers 3
Ali H Brivanlou
the Rockefeller University
Co-authored papers 3
Alex Ignatchenko
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 3
Amander T Clark
Center for Reproductive Science, University of California los angeles
Co-authored papers 3
Monica J Justice
The Hospital for Sick Children
Co-authored papers 3
Release 1.2