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Author Details

Kimberly G Malphrus
Mayo Clinic Florida
2011
25
16
PMIDPaper TitleJournal TitlePublished Year
34813500Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions.J Clin Invest2022
35388616Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations.Aging Cell2022
35307406Transcript levels in plasma contribute substantial predictive value as potential Alzheimer's disease biomarkers in African Americans.EBioMedicine2022
35047668Clinical Deep Phenotyping of <i>ABCA7</i> Mutation Carriers.Neurol Genet2022
33252078Plasma Biomarkers of Alzheimer's Disease in African Americans.J Alzheimers Dis2021
34020725Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.Acta Neuropathol Commun2021
32928256Correction to: Deciphering cellular transcriptional alterations in Alzheimer's disease brains.Mol Neurodegener2020
33092647Association of ABI3 and PLCG2 missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy.Acta Neuropathol Commun2020
32660529Deciphering cellular transcriptional alterations in Alzheimer's disease brains.Mol Neurodegener2020
29107053Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.Alzheimers Dement2018
30136084Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy.Acta Neuropathol2018
30326945ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans.Mol Neurodegener2018
27939925A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.Alzheimers Dement2017
28097223<i>ABCA7</i> loss-of-function variants, expression, and neurologic disease risk.Neurol Genet2017
27115769Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.Acta Neuropathol2016
27727239Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases.Sci Data2016
25189118Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease.Neurobiol Aging2015
27066552Late-onset Alzheimer disease risk variants mark brain regulatory loci.Neurol Genet2015
23643458Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects.Alzheimers Dement2014
25324900Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.Alzheimers Res Ther2014
23750206LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD).PLoS One2013
22494505Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications.Mol Neurodegener2012
22722634Novel late-onset Alzheimer disease loci variants associate with brain gene expression.Neurology2012
22685416Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.PLoS Genet2012
21868378Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region.J Biol Chem2011
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Collaborators

Mayo Clinic
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Center for Clinical and Translational Science, Mayo Clinic
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Mayo Clinic Jacksonville
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Mayo Clinic Florida
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Mayo Clinic Rochester
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Cincinnati Children's Hospital Medical Center
Co-authored papers 7
Mayo Clinic
Co-authored papers 7
Mayo Clinic
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Emory Center for Neurodegenerative Disease
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Mayo Clinic
Co-authored papers 6
Institute for Systems Biology
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Mayo Clinic
Co-authored papers 4
Center for Individualized Medicine, Mayo Clinic
Co-authored papers 4
Institute for Systems Biology
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Emory University School of Medicine
Co-authored papers 3
Cleveland Institute for Computational Biology, Case Western Reserve University
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Mayo Clinic Rochester
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Boston University Chobanian & Avedisian School of Medicine
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