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Author Details

John D Aitchison
Center for Global Infectious Disease Research, Seattle Children's Research Institute
1988
173
55
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37503298Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus.bioRxiv2024
36720309Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2.J Biol Chem2023
37645861Predicting host-based, synthetic lethal antiviral targets from omics data.bioRxiv2023
37398994SUMOylation at the inner nuclear membrane facilitates nuclear envelope biogenesis during mitosis.J Cell Biol2023
37358474Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin.J Cell Biol2023
37195999Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge.PLoS Pathog2023
37293702T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.Clin Infect Dis2023
35108339Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity.PLoS Pathog2022
35738280A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.Cell Chem Biol2022
36591224Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection.Front Immunol2022
36305789Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.J Cell Biol2022
36226962Persistent Nonviral Plasmid Vector in Nasal Tissues Causes False-Positive SARS-CoV-2 Diagnostic Nucleic Acid Tests.Microbiol Spectr2022
36155639Low rate of SARS-CoV-2 incident infection identified by weekly screening PCR in a prospective year-long cohort study.PLoS One2022
33693706Use of a Contained Mycobacterium tuberculosis Mouse Infection Model to Predict Active Disease and Containment in Humans.J Infect Dis2022
35031601Preimmunization correlates of protection shared across malaria vaccine trials in adults.NPJ Vaccines2022
33333016Dissecting the Structural Dynamics of the Nuclear Pore Complex.Mol Cell2021
33851164Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.bioRxiv2021
34874007Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.Elife2021
34788328Angiotensin II receptor I auto-antibodies following SARS-CoV-2 infection.PLoS One2021
34787675Phosphorylation-dependent mitotic SUMOylation drives nuclear envelope-chromatin interactions.J Cell Biol2021
34549725Determinants of brain swelling in pediatric and adult cerebral malaria.JCI Insight2021
34566920Autophagy as a Mechanism for Adaptive Prediction-Mediated Emergence of Drug Resistance.Front Microbiol2021
34243763Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers.Malar J2021
34150934ODELAM: Rapid Sequence-independent Detection of Drug Resistance in <i>Mycobacterium tuberculosis</i> Isolates.Bio Protoc2021
34031149ILF3 Is a Negative Transcriptional Regulator of Innate Immune Responses and Myeloid Dendritic Cell Maturation.J Immunol2021
33142108Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis.Cell Host Microbe2021
33450011A systems-level gene regulatory network model for Plasmodium falciparum.Nucleic Acids Res2021
32401195ODELAM, rapid sequence-independent detection of drug resistance in isolates of <i>Mycobacterium tuberculosis</i>.Elife2020
33173868Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.bioRxiv2020
32997711Defining the proteolytic landscape during enterovirus infection.PLoS Pathog2020
32785687Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality.J Cell Biol2020
32211898Peroxisome prognostications: Exploring the birth, life, and death of an organelle.J Cell Biol2020
32211027Recruitment of an Activated Gene to the Yeast Nuclear Pore Complex Requires Sumoylation.Front Genet2020
31111131Spatial presentation of biological molecules to cells by localized diffusive transfer.Lab Chip2019
31731198Plasmodium Secretion Induces Hepatocyte Lysosome Exocytosis and Promotes Parasite Entry.iScience2019
30893610Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection.Cell Rep2019
31040236Meta-analysis of Plasmodium falciparum <i>var</i> Signatures Contributing to Severe Malaria in African Children and Indian Adults.mBio2019
29539637Integrative structure and functional anatomy of a nuclear pore complex.Nature2018
30378032Characterization of Peroxisomal Regulation Networks.Subcell Biochem2018
29588378ESCRT-III is required for scissioning new peroxisomes from the endoplasmic reticulum.J Cell Biol2018
29496964Involvement in surface antigen expression by a moonlighting FG-repeat nucleoporin in trypanosomes.Mol Biol Cell2018
27856698One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY!G3 (Bethesda)2017
29107642Linking EPCR-Binding PfEMP1 to Brain Swelling in Pediatric Cerebral Malaria.Cell Host Microbe2017
29201016The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria.Front Microbiol2017
28594877An indicator cell assay for blood-based diagnostics.PLoS One2017
28854640Adaptive Prediction Emerges Over Short Evolutionary Time Scales.Genome Biol Evol2017
28715382ODELAY: A Large-scale Method for Multi-parameter Quantification of Yeast Growth.J Vis Exp2017
28520713Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast.PLoS Comput Biol2017
27129769Peroxins Pex30 and Pex29 Dynamically Associate with Reticulons to Regulate Peroxisome Biogenesis from the Endoplasmic Reticulum.J Biol Chem2016
27625397Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.Nucleic Acids Res2016
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Collaborators

Michael P Rout
The Rockefeller University
Co-authored papers 32
Richard A Rachubinski
University of Alberta
Co-authored papers 31
Fred D Mast
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 28
Richard W Wozniak
University of Alberta
Co-authored papers 25
Jennifer J Smith
Institute for Systems Biology
Co-authored papers 25
Brian T Chait
The Rockefeller University
Co-authored papers 20
David J Dilworth
Institute for Systems Biology
Co-authored papers 16
Marcello Marelli
AstraZeneca Oncology R&D
Co-authored papers 14
Maxwell L Neal
Co-authored papers 10
Alexis Kaushansky
Seattle Children's Research Institute, University of Washington
Co-authored papers 9
Nitin S Baliga
Institute for Systems Biology
Co-authored papers 9
Thurston Herricks
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 9
Alan Aderem
Seattle Children's Research Institute
Co-authored papers 7
Stephen A Ramsey
Oregon State University
Co-authored papers 7
David R Goodlett
University of Victoria
Co-authored papers 7
Ilya Shmulevich
Institute for Systems Biology
Co-authored papers 7
David Noah Sather
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 6
Paul Olivier
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 6
Kenneth Stuart
Seattle Children's Research Institute
Co-authored papers 6
Franco J Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 6
Jung-Hsien Chiang
National Cheng Kung University
Co-authored papers 6
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 5
Arti T Navare
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 5
David Feny??
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers 5
Vladimir Vigdorovich
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 5
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 5
Daehee Hwang
Co-authored papers 4
Robert L Moritz
Institute for Systems Biology
Co-authored papers 4
Natalia E Ketaren
The Rockefeller University
Co-authored papers 4
Charles M Rice
Rockefeller University
Co-authored papers 4
Release 1.2