Author details

Full Name

Paul S Frenette

Affiliation

ORCID

Career Start Year

1987

Papers

182

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36711927	Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury.		2023
36183032	Tissue-resident glial cells associate with tumoral vasculature and promote cancer progression.	Angiogenesis	2023
36315910	Dietary iron restriction protects against vaso-occlusion and organ damage in murine sickleÂ cellÂ disease.	Blood	2023
37961493	Haematopoietic stem cell numbers are not solely determined by niche availability.		2023
36585572	Whole bone subcutaneous transplantation as a strategy to study precisely the bone marrow niche.		2023
35065706	The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow.		2022
35636458	Brain motor and fear circuits regulate leukocytes during acute stress.	Nature	2022
35858618	Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.	Cell Stem Cell	2022
35235365	Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.	Science advances	2022
35210567	VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells.	Nat Cell Biol	2022
34993493	Bone marrow NG2<sup>+</sup>/Nestin<sup>+</sup> mesenchymal stem cells drive DTC dormancy <i>via</i> TGFÎ²2.	Nat Cancer	2021
33753857	Using CT-guided stereotactic prostate radiation therapy (CT-SPRT) to assess sustained murine prostate ablation.	Scientific Reports	2021
33947846	MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells.	Nat Commun	2021
33504783	Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1.	Nature Communications	2021
34327335	Future directions in preclinical and translational cancer neuroscience research.	Nat Cancer	2021
33864386	Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease.	British Journal of Pharmacology	2021
33045060	Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage.	Journal of Experimental Medicine	2021
33361809	Nociceptive nerves regulate haematopoietic stem cell mobilization.	Nature	2021
33165861	In Situ Hematopoietic Stem Cell Imaging.	Methods in Molecular Biology	2021
33054107	Very low incidence of infection in pediatric sickle cell disease patients.	Haematologica	2020
32413329	Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.	Dev Cell	2020
32307329	Use of beta-blocker types and risk of incident prostate cancer in a multiethnic population.	Urologic Oncology: Seminars and Original Investigations	2020
32302564	Roadmap for the Emerging Field of Cancer Neuroscience.	Cell	2020
31974491	Nerves in cancer.	Nature Reviews Cancer	2020
32531270	Clinically Actionable Strategies for Studying Neural Influences in Cancer.	Cancer Cell	2020
32631869	Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease Are Amplified by Hydroxyurea: In Vitro and In Vivo Studies.	Journal of Pharmacology and Experimental Therapeutics	2020
32735844	The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation.	Immunity	2020
32951731	Randomized phase 2 trial of Intravenous Gamma Globulin (IVIG) for the treatment of acute vaso-occlusive crisis in patients with sickle cell disease: Lessons learned from the midpoint analysis.	Complementary Therapies in Medicine	2020
30988422	Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells.	Nat Cell Biol	2019
31633216	Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).	Eur J Immunol	2019
31130357	NestinNG2 Cells Form a Reserve Stem Cell Population in the Mouse Prostate.	Stem Cell Reports	2019
30971824	The bone marrow microenvironment at single-cell resolution.	Nature	2019
30745579	Haematopoietic stem cell activity andÂ interactions with the niche.	Nature Reviews Molecular Cell Biology	2019
30903101	Author Correction: Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.	Nat Med	2019
31401849	Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins.	Circulation	2019
30898860	Cross talk between neutrophils and the microbiota.	Blood	2019
30674470	Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands.	Blood	2019
30948854	Seasonal manifestations of sickle cell disease activity.	Nature Medicine	2019
31299217	The good side of inflammation: Staphylococcus aureus proteins SpA and Sbi contribute to proper abscess formation and wound healing during skin and soft tissue infections.	Biochim Biophys Acta Mol Basis Dis	2019
31296938	Author Correction: The bone marrow microenvironment at single-cell resolution.	Nature	2019
29456137	Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches.	Dev Cell	2018
30314756	The Majority of CD45<sup>-</sup>Â Ter119<sup>-</sup>Â CD31<sup>-</sup> Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors.	Immunity	2018
29934585	Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.	Nat Commun	2018
29358215	The hematopoietic stem cell niche: from embryo to adult.	Development (Cambridge)	2018
29669248	Niches for Hematopoietic Stem Cells and Their Progeny.	Immunity	2018
29302031	A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.	Nature Communications	2018
29736022	Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.	Nat Med	2018
29155425	Granulocyte-derived TNFÎ± promotes vascular and hematopoietic regeneration in the bone marrow.	Nature Medicine	2018
29500307	Neural Regulation of Bone and Bone Marrow.	Cold Spring Harbor Perspectives in Medicine	2018
29456159	CD150 Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.		2018