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| 37505680 | Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain. | | 2023 |
| 38041394 | The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b core to form a helical motif that is of ancient origin. | | 2023 |
| 36654747 | Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. | | 2023 |
| 36902100 | Dps (PA0962) Functions in HO Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity. | | 2023 |
| 37146865 | Structure of Rhizobium sp. 4-9 histamine dehydrogenase and analysis of the electron transfer pathway to an abiological electron acceptor. | | 2023 |
| 37140445 | An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression. | Cancer Discov | 2023 |
| 37080108 | Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV). | | 2023 |
| 35304125 | Structure of the Anthrax Protective Antigen D425A Dominant Negative Mutant Reveals a Stalled Intermediate State of Pore Maturation. | J Mol Biol | 2022 |
| 35904259 | Serum-Stable and Selective Backbone-N-Methylated Cyclic Peptides That Inhibit Prokaryotic Glycolytic Mutases. | ACS Chemical Biology | 2022 |
| 35638577 | Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease. | Journal of Medicinal Chemistry | 2022 |
| 35063417 | Improving the kinetic parameters of nicotine oxidizing enzymes by homologous structure comparison and rational design. | Archives of Biochemistry and Biophysics | 2022 |
| 34705594 | Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058. | Journal of Biomolecular Structure and Dynamics | 2022 |
| 34865476 | Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. | Journal of Medicinal Chemistry | 2021 |
| 33812994 | Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases. | Journal of Biological Chemistry | 2021 |
| 34213885 | Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease. | Journal of Medicinal Chemistry | 2021 |
| 34210738 | Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. | Proceedings of the National Academy of Sciences of the United States of America | 2021 |
| 33197096 | Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta. | Protein Science | 2021 |
| 33296226 | Costameric integrin and sarcoglycan protein levels are altered in a model for Limb-girdle muscular dystrophy type 2H. | Molecular Biology of the Cell | 2021 |
| 33269912 | Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Cells. | ACS Infectious Diseases | 2021 |
| 33158944 | The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. | Journal of Virology | 2021 |
| 32945669 | Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. | J Med Chem | 2020 |
| 31637787 | Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation. | Mol Microbiol | 2020 |
| 31603583 | Crystal and solution structures of human oncoprotein Musashi-2â¿¿N-terminal RNA recognition motif 1. | Proteins: Structure, Function and Bioinformatics | 2020 |
| 32747425 | 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. | Science Translational Medicine | 2020 |
| 32908216 | Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor. | Communications Biology | 2020 |
| 32511412 | The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase. | | 2020 |
| 33171806 | Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain. | Toxins | 2020 |
| 33122003 | The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform. | Journal of Molecular Biology | 2020 |
| 30883881 | Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease. | Proteins: Structure, Function and Bioinformatics | 2019 |
| 31038945 | Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity. | Journal of the American Chemical Society | 2019 |
| 31282472 | Crystal structures of the naturally fused CS and cytochrome b reductase (bR) domains of Ncb5or reveal an expanded CS fold, extensive CS-bR interactions and productive binding of the NAD(P) nicotinamide ring. | Acta Crystallographica Section D: Structural Biology | 2019 |
| 30850536 | Crystal structure of human mitochondrial trifunctional protein, a fatty acid β-oxidation metabolon. | Proceedings of the National Academy of Sciences of the United States of America | 2019 |
| 30936373 | Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection. | J Bacteriol | 2019 |
| 28034013 | Crystal structure of Staphylococcus aureus Zn-glyoxalase I: new subfamily of glyoxalase I family. | J Biomol Struct Dyn | 2018 |
| 30183257 | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site. | Biochemistry | 2018 |
| 29227928 | Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease. | Eur J Med Chem | 2018 |
| 29672980 | Using disruptive insertional mutagenesis to identify the in situ structure-function landscape of the Shigella translocator protein IpaB. | Protein Science | 2018 |
| 29544147 | Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. | Eur J Med Chem | 2018 |
| 28038326 | Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease. | Eur J Med Chem | 2017 |
| 28842484 | Single-domain antibodies pinpoint potential targets within invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion. | Journal of Biological Chemistry | 2017 |
| 28368002 | Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases. | Nature Communications | 2017 |
| 29031045 | Structural characterization of the Man5 glycoform of human IgG3 Fc. | Molecular Immunology | 2017 |
| 27914364 | Structure-based exploration and exploitation of the S<sub>4</sub> subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. | Eur J Med Chem | 2017 |
| 27917832 | 1.45⿿ÿ resolution structure of SRPN18 from the malaria vector Anopheles gambiae. | Acta Crystallogr F Struct Biol Commun | 2016 |
| 27235842 | Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies. | Eur J Med Chem | 2016 |
| 27050257 | Crystal structure of histone-like protein from Streptococcus mutans refined to 1.9⿿ÿ resolution. | Acta Crystallographica Section F:Structural Biology Communications | 2016 |
| 26823007 | Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease. | J Med Chem | 2016 |
| 27074415 | Replacing Arginine 33 for Alanine in the Hemophore HasA from Pseudomonas aeruginosa Causes Closure of the H32 Loop in the Apo-Protein. | Biochemistry | 2016 |
| 27599865 | 1.65⿿ÿ resolution structure of the AraC-family transcriptional activator ToxT from Vibrio cholerae. | Acta Crystallographica Section F:Structural Biology Communications | 2016 |
| 26368531 | Characterization of the Bacterioferritin/Bacterioferritin Associated Ferredoxin Protein-Protein Interaction in Solution and Determination of Binding Energy Hot Spots. | Biochemistry | 2015 |