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Author Details

Fran??oise R??dini
Nantes Universite, Inserm UMR 7, CNRS UMR 6075, Universite d'Angers
1986
177
48
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36831348Characterization of the Tumor Microenvironment in Jaw Osteosarcomas, towards Prognostic Markers and New Therapeutic Targets.Cancers (Basel)2023
37719019MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells.Front Oncol2023
37752913Ewing sarcoma from molecular biology to the clinic.Front Cell Dev Biol2023
35337159Tumor Suppressive Role of miR-342-5p and miR-491-5p in Human Osteosarcoma Cells.Pharmaceuticals (Basel)2022
35530297Signature of the vascular tumor microenvironment as a marker of the therapeutic response to doxorubicin in a preclinical model of osteosarcoma.Am J Cancer Res2022
36428719TRAIL-Based Therapies Efficacy in Pediatric Bone Tumors Models Is Modulated by TRAIL Non-Apoptotic Pathway Activation via RIPK1 Recruitment.Cancers (Basel)2022
35326631Together Intra-Tumor Hypoxia and Macrophagic Immunity Are Driven Worst Outcome in Pediatric High-Grade Osteosarcomas.Cancers (Basel)2022
34062831ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells.Pharmaceuticals (Basel)2021
33498676Characterization of Macrophages and Osteoclasts in the Osteosarcoma Tumor Microenvironment at Diagnosis: New Perspective for Osteosarcoma Treatment?Cancers (Basel)2021
34944050LIM Kinases in Osteosarcoma Development.Cells2021
34885102Pyridazinone Derivatives Limit Osteosarcoma-Cells Growth In Vitro and In Vivo.Cancers (Basel)2021
34765560Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis.Front Oncol2021
34571917Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619.Cells2021
34678225Ubiquitin-specific proteases as therapeutic targets in paediatric primary bone tumours?Biochem Pharmacol2021
32164350Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers?Cancers (Basel)2020
33228057Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing's Sarcoma Tumor Growth.Cancers (Basel)2020
33113487Osteosarcoma of the jaws: An overview of the pathophysiological mechanisms.Crit Rev Oncol Hematol2020
33419295The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth.Cancers (Basel)2020
32859065Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors.Biomolecules2020
32110934SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression.Cells2020
32326444The Osteosarcoma Microenvironment: A Complex But Targetable Ecosystem.Cells2020
3104535112b80 - Hydroxybisphosphonate Linked Doxorubicin: Bone Targeted Strategy for Treatment of Osteosarcoma.Bioconjug Chem2019
31717935Epinephrine Infiltration of Adipose Tissue Impacts MCF7 Breast Cancer Cells and Total Lipid Content.Int J Mol Sci2019
31604924Integrated molecular characterization of chondrosarcoma reveals critical determinants of disease progression.Nat Commun2019
31260659Genetically-achieved disturbances to the expression levels of TNFSF11 receptors modulate the effects of zoledronic acid on growing mouse skeletons.Biochem Pharmacol2019
31370265New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?Int J Mol Sci2019
30813941Jaw osteosarcoma models in mice: first description.J Transl Med2019
29190507Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study.Eur J Cancer2018
30093324In vitro and in vivo discrepancy in inducing apoptosis by mesenchymal stromal cells delivering membrane-bound tumor necrosis factor-related apoptosis inducing ligand in osteosarcoma pre-clinical models.Cytotherapy2018
30413057Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups.J Clin Med2018
29761075Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment.Front Oncol2018
29323712Paradoxical side effects of bisphosphonates on the skeleton: What do we know and what can we do?J Cell Physiol2018
28932633CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 phase 3 trial.Oncoimmunology2017
29221170Proteoglycan-targeting applied to hypoxia-activated prodrug therapy in chondrosarcoma: first proof-of-concept.Oncotarget2017
29218254Bone microenvironment has an influence on the histological response of osteosarcoma to chemotherapy: retrospective analysis and preclinical modeling.Am J Cancer Res2017
28707014Doxycycline and its quaternary ammonium derivative for adjuvant therapies of chondrosarcoma.Cancer Chemother Pharmacol2017
27006472Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.Oncotarget2016
27863724[Which approach of therapeutic education (TE) for adolescents and young adults with cancer? Experience from the TE working group of "Go-AJA"].Bull Cancer2016
27827889TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression.J Clin Med2016
27558972TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models.Int J Cancer2016
27324280Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial.Lancet Oncol2016
27573424Proteoglycans as Target for an Innovative Therapeutic Approach in Chondrosarcoma: Preclinical Proof of Concept.Mol Cancer Ther2016
27519659Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw.J Craniomaxillofac Surg2016
27315524The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report.Clin Sarcoma Res2016
27152244L-MTP-PE and zoledronic acid combination in osteosarcoma: preclinical evidence of positive therapeutic combination for clinical transfer.Am J Cancer Res2016
26910666Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells.Plast Reconstr Surg2016
26802024The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.Oncotarget2016
26712686Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.Clin Cancer Res2016
24961790BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma.Int J Cancer2015
26779435Bone Tumor Environment as a Potential Therapeutic Target in Ewing Sarcoma.Front Oncol2015
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Collaborators

Cancer Center of Lyon
Co-authored papers 12
University Hospital of Tours
Co-authored papers 7
Co-authored papers 6
Universite Paris-Saclay
Co-authored papers 6
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 6
Institut Curie, Inserm, CNRS, Universite Paris-Saclay
Co-authored papers 4
Children's Cancer Research Center
Co-authored papers 3
St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 3
University Hospital Essen, West German Cancer Center
Co-authored papers 3
Centre Leon Berard & Universite Claude Bernard
Co-authored papers 3
University Hospital Erlangen
Co-authored papers 3
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 3
The Jackson Laboratory Cancer Center
Co-authored papers 2
Servicio de Anatomia Patologica. Hospital Universitario Virgen del Rocio.
Co-authored papers 2
British Columbia Cancer Research Centre
Co-authored papers 2
Osteosarcoma Institute
Co-authored papers 2
Institut d'Investigacio Biomedica de Bellvitge (IDIBELL)/CIBERONC
Co-authored papers 2
Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna
Co-authored papers 2
Children's Cancer Research Institute
Co-authored papers 2
Seattle Children's Research Institute
Co-authored papers 2
Georgetown University Medical Center, Georgetown University
Co-authored papers 2
Co-authored papers 2
University Children's Hospital Muenster
Co-authored papers 2
The Ohio State University College of Medicine
Co-authored papers 2
Department of Oncology and Children's Research Center, University Children's Hospital
Co-authored papers 2
Technische Universitat Munchen
Co-authored papers 2
Tohoku University Graduate School of Medicine
Co-authored papers 1
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Dana-Farber Cancer Institute
Co-authored papers 1
Co-authored papers 1