Skip to Main Content

Author Details

Dong-Er Zhang
Moores Cancer Center, University of California San Diego
1986
187
69
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37838757Single-cell RNA sequencing of a new transgenic t(8;21) preleukemia mouse model reveals regulatory networks promoting leukemic transformation.Leukemia2024
36646704Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis.Nat Commun2023
37547001Chromatin-associated RNA Dictates the ecDNA Interactome in the Nucleus.bioRxiv2023
37577681Interface-guided phenotyping of coding variants in the transcription factor RUNX1 with SEUSS.bioRxiv2023
34845316Acute myeloid leukemia cell membrane-coated nanoparticles for cancer vaccination immunotherapy.Leukemia2022
37082605<i>C11orf21</i>, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO.BBA Adv2022
36206200RUNX1 deficiency cooperates with SRSF2 mutation to induce multilineage hematopoietic defects characteristic of MDS.Blood Adv2022
35879727ZetaSuite: computational analysis of two-dimensional high-throughput data from multi-target screens and single-cell transcriptomics.Genome Biol2022
34482400Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia.Blood2022
33531067MicroRNA let-7b downregulates AML1-ETO oncogene expression in t(8;21) AML by targeting its 3'UTR.Exp Hematol Oncol2021
33656539A CRISPR RNA-binding protein screen reveals regulators of RUNX1 isoform generation.Blood Adv2021
32945770Cell-cycle-gated feedback control mediates desensitization to interferon stimulation.Elife2020
32029705The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling.Blood Cancer J2020
31974171Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing.Cancer Discov2020
31434702Hippo kinase loss contributes to del(20q) hematologic malignancies through chronic innate immune activation.Blood2019
29395063The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.Mol Cell2018
30266866The probacterial effect of type I interferon signaling requires its own negative regulator USP18.Sci Immunol2018
29674496GFI1 is required for <i>RUNX1/ETO</i> positive acute myeloid leukemia.Haematologica2018
29751735Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants.SLAS Discov2018
29357192Negative regulation of type I IFN signaling.J Leukoc Biol2018
27389055Restoration of MYC-repressed targets mediates the negative effects of GM-CSF on RUNX1-ETO leukemogenicity.Leukemia2017
28165510STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.Nat Struct Mol Biol2017
29104020R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.Mol Cell2017
27885273Fatty acid-binding protein FABP4 mechanistically links obesity with aggressive AML by enhancing aberrant DNA methylation in AML cells.Leukemia2017
27015284Loss of RUNX1 function results in enhanced granulocyte-colony-stimulating factor-mediated mobilization.Blood Cancer J2016
27809302Multiple functions of USP18.Cell Death Dis2016
27655702Sex chromosome loss and the pseudoautosomal region genes in hematological malignancies.Oncotarget2016
27801882USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.Cell Res2016
27492256Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators.RNA2016
27545680De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome.Am J Hum Genet2016
27016605Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice.J Immunol2016
25406959Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.J Interferon Cytokine Res2015
26515094Type I IFN induces protein ISGylation to enhance cytokine expression and augments colonic inflammation.Proc Natl Acad Sci U S A2015
26046984USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2.PLoS One2015
26124281SRSF2 Is Essential for Hematopoiesis, and Its Myelodysplastic Syndrome-Related Mutations Dysregulate Alternative Pre-mRNA Splicing.Mol Cell Biol2015
26226047Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis.Sci Rep2015
25727291AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation.Leukemia2015
23772668RUNX1-ETO induces a type I interferon response which negatively effects t(8;21)-induced increased self-renewal and leukemia development.Leuk Lymphoma2014
25995992Plakophilin-2 induced EGFR phosphorylation: a focus on the intracellular activators of EGFR.Receptors Clin Investig2014
25326705Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome.Nat Struct Mol Biol2014
25150295Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.Blood2014
25113560Plakophilin-2 promotes tumor development by enhancing ligand-dependent and -independent epidermal growth factor receptor dimerization and activation.Mol Cell Biol2014
24807690Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections.Genes Immun2014
24771859Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice.Blood2014
22964713ISG15 regulates IFN-γ immunity in human mycobacterial disease.Cell Res2013
24130502Cooperation between RUNX1-ETO9a and novel transcriptional partner KLF6 in upregulation of Alox5 in acute myeloid leukemia.PLoS Genet2013
24124051Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.EMBO Mol Med2013
24204252Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.PLoS Pathog2013
23825189USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex.J Exp Med2013
23907698Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles.Nanoscale2013
  • 1 - 50 of 187

Recommended Authors

Nan Zhu
Shanghai General Hospital, Shanghai Jiaotong University
Career Start Year 2007
Number of shared co-authors 2
Marc A Kerenyi
Boston Children's Hospital, Harvard Medical School
Career Start Year 2006
Number of shared co-authors 2
Christopher Y Park
NYU Robert I. Grossman School of Medicine
Career Start Year 2006
Number of shared co-authors 2
Maggie Cam
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 2005
Number of shared co-authors 0
Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2005
Number of shared co-authors 7
Fumio Nakahara
Graduate School of Medicine, The University of Tokyo
Career Start Year 2004
Number of shared co-authors 2
Andrew V Kossenkov
The Wistar Institute
Career Start Year 2003
Number of shared co-authors 1
Andreas Lennartsson
Karolinska Institute
Career Start Year 2003
Number of shared co-authors 0
Ernesto Guccione
Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Career Start Year 2001
Number of shared co-authors 4
Shinichiro Takahashi
Tohoku Medical and Pharmaceutical University Hospital.
Career Start Year 1998
Number of shared co-authors 0
Alex Kentsis
Memorial Sloan-Kettering Cancer Center
Career Start Year 1998
Number of shared co-authors 2
Kevin S Smith
Stanford University
Career Start Year 1997
Number of shared co-authors 1
Dongquan Chen
University of Alabama at Birmingham
Career Start Year 1997
Number of shared co-authors 1
Stephanie Halene
Smilow Cancer Center, Yale University School of Medicine
Career Start Year 1997
Number of shared co-authors 2
Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 0
Claus Nerlov
MRC Weatherall Institute of Molecular Medicine, University of Oxford
Career Start Year 1990
Number of shared co-authors 2
Scott A Armstrong
Boston Children's Hospital
Career Start Year 1990
Number of shared co-authors 6
Dirk Geerts
Amsterdam University Medical Center
Career Start Year 1989
Number of shared co-authors 0
Geoffrey Neale
St. Jude Children's Research Hospital
Career Start Year 1989
Number of shared co-authors 0
Guy Sauvageau
Universite de Montreal
Career Start Year 1988
Number of shared co-authors 1
Kristian Helin
The Institute of Cancer Research
Career Start Year 1988
Number of shared co-authors 1
Takuro Nakamura
Tohoku University Graduate School of Medicine
Career Start Year 1987
Number of shared co-authors 0
Yoshiaki Ito
Tokyo Medical and Dental University (TMDU)
Career Start Year 1987
Number of shared co-authors 2
Harukazu Suzuki
RIKEN Center for Integrative Medical Sciences
Career Start Year 1985
Number of shared co-authors 1
Toshio Kitamura
The University of Tokyo.
Career Start Year 1984
Number of shared co-authors 3
Timothy J Ley
Washington University School of Medicine
Career Start Year 1982
Number of shared co-authors 0
Daniel C Link
Washington University School of Medicine
Career Start Year 1982
Number of shared co-authors 1
Michael C Ostrowski
Hollings Cancer Center, Medical University of South Carolina
Career Start Year 1979
Number of shared co-authors 0
Hiroshi Handa
Center for Future Medical Research, Tokyo Medical University
Career Start Year 1975
Number of shared co-authors 0
Bruce J Aronow
Cincinnati Children's Hospital Medical Center
Career Start Year 1975
Number of shared co-authors 3

Collaborators

Daniel G Tenen
Harvard Stem Cell Institute, Harvard Medical School
Co-authored papers 30
Xiang-Dong Fu
Co-authored papers 11
Deborah J Lenschow
Co-authored papers 4
Rafael Bejar
Moores Cancer Center, university of california san diego
Co-authored papers 3
Klaus-Peter Knobeloch
Co-authored papers 3
Hannah Carter
University of California San Diego
Co-authored papers 2
Zhaohui Ye
Center for Biologics Evaluation and Research
Co-authored papers 2
Gen-Sheng Feng
Co-authored papers 2
Torsten Haferlach
Taussig Cancer Institute, Cleveland Clinic
Co-authored papers 2
Christopher K Glass
University of California San Diego
Co-authored papers 2
Jia-Yu Chen
Co-authored papers 2
Nancy A Speck
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Bing Ren
Center for Epigenomics, University of California San Diego
Co-authored papers 2
Atsushi Iwama
Co-authored papers 2
Linzhao Cheng
Johns Hopkins University School of Medicine
Co-authored papers 2
James Palis
Co-authored papers 2
Etienne Richer
Canadian Institutes of Health Research Institute of Genetics
Co-authored papers 2
Jun Lu
Yale University
Co-authored papers 1
Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
Co-authored papers 1
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 1
Luis Rohena
Co-authored papers 1
Kun-Liang Guan
University of California San Diego
Co-authored papers 1
Clesson Turner
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 1
Kelly Schoch
Duke University School of Medicine
Co-authored papers 1
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 1
Jeanna Sheen
Co-authored papers 1
Michael Q Zhang
The University of Texas at Dallas
Co-authored papers 1
Zejuan Li
Houston Methodist Hospital
Co-authored papers 1
Megan T Cho
Co-authored papers 1
Hao Zhang
Co-authored papers 1
Release 1.2