Author details

Full Name

Orr Ashenberg

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37425718	A cellular and spatial atlas of <i>TP53</i> -associated tissue remodeling in lung adenocarcinoma.	bioRxiv	2024
36720220	The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.	Immunity	2023
38091954	The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.	Immunity	2023
37344597	B-cell-specific checkpoint molecules that regulate anti-tumour immunity.	Nature	2023
37495702	Author Correction: A single-cell atlas of human and mouse white adipose tissue.	Nature	2023
35296864	A single-cell atlas of human and mouse white adipose tissue.	Nature	2022
35906236	Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.	Nat Commun	2022
35902743	Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.	Nat Genet	2022
35803260	Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy.	Cell	2022
35549429	Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function.	Science	2022
36324805	A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.	bioRxiv	2022
34588693	Blood and immune development in human fetal bone marrow and Down syndrome.	Nature	2021
33592174	Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.	Cell	2021
33655247	A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.	bioRxiv	2021
33654293	Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.	Nat Med	2021
33915569	COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.	Nature	2021
32663469	Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma.	Cancer Cell	2020
32304633	Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.	Immunity	2020
32707077	Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.	Cancer Cell	2020
32755564	A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq.	Mol Ther	2020
32572264	A single-cell landscape of high-grade serous ovarian cancer.	Nat Med	2020
32719530	Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq.	Nat Methods	2020
31130381	A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia.	Cell	2019
31597962	Decoding human fetal liver haematopoiesis.	Nature	2019
31618654	Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide Î±-CGRP Modulates Group 2 Innate Lymphoid Cell Responses.	Immunity	2019
30185635	Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity.	J Exp Med	2018
30222731	Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones.	PLoS Biol	2018
30392957	T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.	Cell	2018
30388455	A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.	Cell	2018
28346537	Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA.	PLoS Pathogens	2017
26226986	Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs.	Molecular Biology and Evolution	2015
23333741	Helix bundle loops determine whether histidine kinases autophosphorylate in cis or in trans.	J Mol Biol	2013
24324165	Mutational effects on stability are largely conserved during protein evolution.	Proceedings of the National Academy of Sciences of the United States of America	2013
23422431	Using analyses of amino Acid coevolution to understand protein structure and function.	Methods Enzymol	2013
23661758	Networks of bZIP protein-protein interactions diversified over a billion years of evolution.	Science	2013
23078131	Spatial tethering of kinases to their substrates relaxes evolutionary constraints on specificity.	Mol Microbiol	2012
21854787	Determinants of homodimerization specificity in histidine kinases.	J Mol Biol	2011
20602445	Identifying and reducing error in cluster-expansion approximations of protein energies.	Journal of Computational Chemistry	2010
21124821	Systematic dissection and trajectory-scanning mutagenesis of the molecular interface that ensures specificity of two-component signaling pathways.	PLoS Genet	2010
18555780	Rewiring the specificity of two-component signal transduction systems.	Cell	2008
17566105	Quantifying fitness distributions and phenotypic relationships in recombinant yeast populations.	Proc Natl Acad Sci U S A	2007
17848524	Robust protein protein interactions in crowded cellular environments.	Proc Natl Acad Sci U S A	2007
16384916	A simple physical model for scaling in protein-protein interaction networks.	Proc Natl Acad Sci U S A	2006