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Author Details

Howard L McLeod
Center for Precision Medicine and Functional Genomics, Utah Tech University
1979
579
95
PMIDPaper TitleJournal TitlePublished Year
36049896Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype.Clin Pharmacol Ther2023
36049896Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype.Clin Pharmacol Ther2023
37698371CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.Pharmacotherapy2023
37552307Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma.J Cancer Res Clin Oncol2023
36821823<i>DPYD</i> Testing: Time to Put Patient Safety First.J Clin Oncol2023
37371044Pharmacogenomic Analyses Implicate B Cell Developmental Status and <i>MKL1</i> as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy.Cells2023
37242540<i>MKX-AS1</i> Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients.Pharmaceuticals (Basel)2023
37242509<i>RYK</i> Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients.Pharmaceuticals (Basel)2023
37552307Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma.J Cancer Res Clin Oncol2023
37698371CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.Pharmacotherapy2023
37242540<i>MKX-AS1</i> Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients.Pharmaceuticals (Basel)2023
37242509<i>RYK</i> Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients.Pharmaceuticals (Basel)2023
37371044Pharmacogenomic Analyses Implicate B Cell Developmental Status and <i>MKL1</i> as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy.Cells2023
36821823<i>DPYD</i> Testing: Time to Put Patient Safety First.J Clin Oncol2023
34616010Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.Br J Cancer2022
35895125Dissecting the role of cell signaling versus CD8<sup>+</sup> T cell modulation in propranolol antitumor activity.J Mol Med (Berl)2022
36092839Propranolol suppresses bladder cancer by manipulating intracellular pH via NHE1.Transl Androl Urol2022
35999636A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma.Mol Cancer2022
36116741PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer.Cancer Lett2022
36579594The Development of an Infrastructure to Facilitate the Use of Whole Genome Sequencing for Population Health.J Pers Med2022
34853435Correction: Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.Br J Cancer2022
34616010Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.Br J Cancer2022
35230418Comparison of FDA Table of Pharmacogenetic Associations and Clinical Pharmacogenetics Implementation Consortium guidelines.Am J Health Syst Pharm2022
34998046UGT1A1 genotype-guided dosing of irinotecan: A prospective safety and cost analysis in poor metaboliser patients.Eur J Cancer2022
36579594The Development of an Infrastructure to Facilitate the Use of Whole Genome Sequencing for Population Health.J Pers Med2022
35999636A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma.Mol Cancer2022
35895125Dissecting the role of cell signaling versus CD8<sup>+</sup> T cell modulation in propranolol antitumor activity.J Mol Med (Berl)2022
36092839Propranolol suppresses bladder cancer by manipulating intracellular pH via NHE1.Transl Androl Urol2022
36116741PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer.Cancer Lett2022
34853435Correction: Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.Br J Cancer2022
34998046UGT1A1 genotype-guided dosing of irinotecan: A prospective safety and cost analysis in poor metaboliser patients.Eur J Cancer2022
35230418Comparison of FDA Table of Pharmacogenetic Associations and Clinical Pharmacogenetics Implementation Consortium guidelines.Am J Health Syst Pharm2022
32958699Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance).Clin Cancer Res2021
33841621Budget Impact of Adaptive Abiraterone Therapy for Castration-Resistant Prostate Cancer.Am Health Drug Benefits2021
34149004Pharmacogenetic study in gastric cancer patients treated with adjuvant fluorouracil/leucovorin or epirubicin/cisplatin/fluorouracil before and after chemoradiation on CALGB 80101 (Alliance).Pharmacogenet Genomics2021
33981600Clinical Use of Propranolol Reduces Biomarkers of Proliferation in Gastric Cancer.Front Oncol2021
34250383Identification of Targetable Gene Fusions and Structural Rearrangements to Foster Precision Medicine in <i>KRAS</i> Wild-Type Pancreatic Cancer.JCO Precis Oncol2021
33863751A Type 2 Diabetes Subtype Responsive to ACCORD Intensive Glycemia Treatment.Diabetes Care2021
32958699Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance).Clin Cancer Res2021
32941389Race and smoking status associated with paclitaxel drug response in patient-derived lymphoblastoid cell lines.Pharmacogenet Genomics2021
34516388Correction: Effect of Physician-Pharmacist Participation in the Management of Ambulatory Cancer Pain Through a Digital Health Platform: Randomized Controlled Trial.JMIR Mhealth Uhealth2021
34398796Effect of Physician-Pharmacist Participation in the Management of Ambulatory Cancer Pain Through a Digital Health Platform: Randomized Controlled Trial.JMIR Mhealth Uhealth2021
34721024β-Adrenergic Receptor Inhibitor and Oncolytic Herpesvirus Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects on Colorectal Cancer.Front Pharmacol2021
34608812The need to shift pharmacogenetic research from candidate gene to genome-wide association studies.Pharmacogenomics2021
34437536High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.PLoS Genet2021
34841710Analytics of the clinical implementation of pharmacogenomics testing in 12 758 individuals.Clin Transl Med2021
34544479β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.Cell Biosci2021
33841621Budget Impact of Adaptive Abiraterone Therapy for Castration-Resistant Prostate Cancer.Am Health Drug Benefits2021
33863751A Type 2 Diabetes Subtype Responsive to ACCORD Intensive Glycemia Treatment.Diabetes Care2021
34437536High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.PLoS Genet2021
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Collaborators

Alison A Motsinger-Reif
National Institute of Environmental Health Sciences
Co-authored papers 31
Mark J Ratain
University of Chicago
Co-authored papers 28
Mary V Relling
Departments of Pharmaceutical Sciences.
Co-authored papers 24
Teri E Klein
Stanford University
Co-authored papers 22
William E Evans
Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 21
Kouros Owzar
Duke University
Co-authored papers 18
Michiaki Kubo
Co-authored papers 13
Russ B Altman
Stanford University
Co-authored papers 13
Deanna L Kroetz
University of California San Francisco
Co-authored papers 12
James Todd Auman
Co-authored papers 12
Dan M Roden
Vanderbilt University Medical Center
Co-authored papers 11
Lisa A Carey
Co-authored papers 10
Michael A Province
Co-authored papers 10
James K Hicks
H. Lee Moffitt Cancer Center and Research Institute
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Mark A Watson
Washington University School of Medicine
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Kathleen M Giacomini
University of California San Francisco
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Ronald M Krauss
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Marc S Williams
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Ramaswamy Govindan
Siteman Cancer Center, Washington University School of Medicine
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John A Spertus
University of Missouri-Kansas City School of Medicine
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Robert R Freimuth
Center for Individualized Medicine, Mayo Clinic
Co-authored papers 8
Joseph G Ibrahim
University of North Carolina
Co-authored papers 8
Richard M Weinshilboum
Mayo Clinic
Co-authored papers 8
Julie A Johnson
Department of Pharmacotherapy and Translational Research, University of Florida
Co-authored papers 8
Alex Sparreboom
Ohio State University
Co-authored papers 8
Patricia A Deverka
Deverka Consulting LLC
Co-authored papers 7
Karen E Weck
University of North Carolina at Chapel Hill
Co-authored papers 7
Gillian C Bell
Mission Health Personalized Medicine & Pharmacogenomics Program
Co-authored papers 7
Geoffrey S Ginsburg
National Institutes of Health
Co-authored papers 7
Deepak Voora
Durham VA Healthcare System and Duke University
Co-authored papers 7
Release 1.2