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Author Details
Full Name
Jorge Eduardo Fajardo
Affiliation
Albert Einstein College of Medicine
ORCID
Career Start Year
1982
Papers
55
H Index
23
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36920074
MAT Gain of Activity Mutation in <i>Helicobacter pylori</i> Is Associated with Resistance to MTAN Transition State Analogues.
ACS Infect Dis
2023
37603727
Optimal selection of suitable templates in protein interface prediction.
Bioinformatics
2023
37101376
Chi3l1 Is a Modulator of Glioma Stem Cell States and a Therapeutic Target in Glioblastoma.
Cancer Res
2023
34499117
INTERCAAT: identifying interface residues between macromolecules.
Bioinformatics
2022
35523180
Subventricular zone adult mouse neural stem cells require insulin receptor for self-renewal.
Stem Cell Reports
2022
36070306
Effects of the COVID-19 pandemic in higher education: A data driven analysis for the knowledge acquisition process.
PLoS One
2022
35879651
Integrated structure-based protein interface prediction.
BMC Bioinformatics
2022
33486430
Residue-based pharmacophore approaches to study protein-protein interactions.
Curr Opin Struct Biol
2021
33684100
miRNA-mediated loss of m6A increases nascent translation in glioblastoma.
PLoS Genet
2021
31298437
Discovery of receptor-ligand interfaces in the immunoglobulin superfamily.
Proteins
2020
31977133
Assessment of chemical-crosslink-assisted protein structure modeling in CASP13.
Proteins
2020
33027689
A Designer Quest for the Achilles' Heel of Influenza.
Structure
2020
30615604
Protein-protein binding supersites.
PLoS Comput Biol
2019
31587357
Assessing the accuracy of contact predictions in CASP13.
Proteins
2019
31569265
Assessment of chemical-crosslink-assisted protein structure modeling in CASP13.
Proteins
2019
30353164
Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor.
Oncogene
2019
29440412
Genetic resistance to purine nucleoside phosphorylase inhibition in <i>Plasmodium falciparum</i>.
Proc Natl Acad Sci U S A
2018
28640909
HIV-Tat regulates macrophage gene expression in the context of neuroAIDS.
PLoS One
2017
27017927
Nuc-ErbB3 regulates H3K27me3 levels and HMT activity to establish epigenetic repression during peripheral myelination.
Glia
2016
24356912
Crk at the quarter century mark: perspectives in signaling and cancer.
J Cell Biochem
2014
23433045
Protein structure based prediction of catalytic residues.
BMC Bioinformatics
2013
20737437
Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.
Proteins
2010
19523904
PSI-2: structural genomics to cover protein domain family space.
Structure
2009
17517764
M4T: a comparative protein structure modeling server.
Nucleic Acids Res
2007
17823132
Comparative protein structure modeling by combining multiple templates and optimizing sequence-to-structure alignments.
Bioinformatics
2007
16388575
Pentapeptide repeat proteins.
Biochemistry
2006
16928737
MMM: a sequence-to-structure alignment protocol.
Bioinformatics
2006
16158059
Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.
Oncogene
2005
15133031
A novel role for the immunophilin FKBP52 in copper transport.
J Biol Chem
2004
15489337
High-throughput computational and experimental techniques in structural genomics.
Genome Res
2004
11242120
Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genome.
Nat Genet
2001
11314030
Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.
Oncogene
2001
10825157
Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis.
J Biol Chem
2000
7657647
v-Crk modulation of growth factor-induced PC12 cell differentiation involves the Src homology 2 domain of v-Crk and sustained activation of the Ras/mitogen-activated protein kinase pathway.
J Biol Chem
1995
7509449
Expression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathways.
Mol Cell Biol
1994
7504172
A 31-amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins.
Mol Cell Biol
1993
8345978
Antimicrobial treatment of occult bacteremia: a multicenter cooperative study.
Pediatr Infect Dis J
1993
8345385
Failure of intrapartum antibiotics to prevent culture-proved neonatal group B streptococcal sepsis.
J Perinatol
1993
8403745
False-negative urine latex particle agglutination testing in neonates with group B streptococcal bacteremia. A function of improper test implementation?
Clin Pediatr (Phila)
1993
7687742
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.
Mol Cell Biol
1993
1280326
The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels.
Mol Cell Biol
1992
1375224
Tyrosine-phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze Crk-phosphotyrosine-dependent interactions in vitro.
J Biol Chem
1992
2121951
Comparison of mupirocin and erythromycin in the treatment of impetigo.
J Pediatr
1990
1966840
Effects of elongation on the translation of a reovirus bicistronic mRNA.
Enzyme
1990
2296589
Translation of bicistronic viral mRNA in transfected cells: regulation at the level of elongation.
Proc Natl Acad Sci U S A
1990
2712937
Inappropriate antidiuretic hormone in children with viral meningitis.
Pediatr Neurol
1989
2540453
Tropical splenomegaly syndrome associated with cytomegalovirus infection.
Mil Med
1989
3495039
Pleural empyema in children: a nationwide retrospective study.
South Med J
1987
3763423
Suppurative arthritis and hemophilia.
Pediatr Infect Dis
1986
3876546
Sudden death due to acute epiglottitis.
Pediatr Infect Dis
1985
1 - 50 of 55
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Co-authored papers
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Cezary Czaplewski
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Emilia A Lubecka
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2
Adam Liwo
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2
Narayanan Eswar
University of California at San Francisco
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Agnieszka Karczyſska
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Stefan Bekiranov
University of Virginia
Co-authored papers
1
Hong Li
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Matthew W Vetting
Albert Einstein College of Medicine
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David Baker
University of Washington
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Lewis C Cantley
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1
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