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Author Details

John T Chang
University of California San Diego
1999
82
36
PMIDPaper TitleJournal TitlePublished Year
36662860A tissue atlas of ulcerative colitis revealing evidence of sex-dependent differences in disease-driving inflammatory cell types and resistance to TNF inhibitor therapy.Sci Adv2023
37598341IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function.Cell Rep2023
37597518A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function.Immunity2023
37648857Metabolic programs of T cell tissue residency empower tumour immunity.Nature2023
36716323Early transcriptional and epigenetic divergence of CD8+ T cells responding to acute versus chronic infection.PLoS Biol2023
36580919Small intestine and colon tissue-resident memory CD8<sup>+</sup> T cells exhibit molecular heterogeneity and differential dependence on Eomes.Immunity2023
37265401Regulation of CD8 T Cell Differentiation by the RNA-Binding Protein DDX5.J Immunol2023
36865314Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity.bioRxiv2023
37235748Responsiveness to Vedolizumab Therapy in Ulcerative Colitis is Associated With Alterations in Immune Cell-Cell Communications.Inflamm Bowel Dis2023
36854061Identification of CD8 + T-Cell-Immune Cell Communications in Ileal Crohn's Disease.Clin Transl Gastroenterol2023
36662860A tissue atlas of ulcerative colitis revealing evidence of sex-dependent differences in disease-driving inflammatory cell types and resistance to TNF inhibitor therapy.Sci Adv2023
37598341IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function.Cell Rep2023
37597518A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function.Immunity2023
37648857Metabolic programs of T cell tissue residency empower tumour immunity.Nature2023
37235748Responsiveness to Vedolizumab Therapy in Ulcerative Colitis is Associated With Alterations in Immune Cell-Cell Communications.Inflamm Bowel Dis2023
37265401Regulation of CD8 T Cell Differentiation by the RNA-Binding Protein DDX5.J Immunol2023
36854061Identification of CD8 + T-Cell-Immune Cell Communications in Ileal Crohn's Disease.Clin Transl Gastroenterol2023
36716323Early transcriptional and epigenetic divergence of CD8+ T cells responding to acute versus chronic infection.PLoS Biol2023
36580919Small intestine and colon tissue-resident memory CD8<sup>+</sup> T cells exhibit molecular heterogeneity and differential dependence on Eomes.Immunity2023
36865314Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity.bioRxiv2023
35294872RORγt phosphorylation protects against T cell-mediated inflammation.Cell Rep2022
35593887The long noncoding RNA Malat1 regulates CD8+ T cell differentiation by mediating epigenetic repression.J Exp Med2022
36156073Systems-level identification of key transcription factors in immune cell specification.PLoS Comput Biol2022
35378331The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.Cell Mol Gastroenterol Hepatol2022
35294872RORγt phosphorylation protects against T cell-mediated inflammation.Cell Rep2022
35347100Preserved SARS-CoV-2 Vaccine Cell-Mediated Immunogenicity in Patients With Inflammatory Bowel Disease on Immune-Modulating Therapies.Clin Transl Gastroenterol2022
35378331The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.Cell Mol Gastroenterol Hepatol2022
35347100Preserved SARS-CoV-2 Vaccine Cell-Mediated Immunogenicity in Patients With Inflammatory Bowel Disease on Immune-Modulating Therapies.Clin Transl Gastroenterol2022
35593887The long noncoding RNA Malat1 regulates CD8+ T cell differentiation by mediating epigenetic repression.J Exp Med2022
36156073Systems-level identification of key transcription factors in immune cell specification.PLoS Comput Biol2022
33440136Clone Wars: Survival of the Fittest CD8<sup>+</sup> Trm Cells.Immunity2021
34253728Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease.Nat Commun2021
33440136Clone Wars: Survival of the Fittest CD8<sup>+</sup> Trm Cells.Immunity2021
33104169Distinct integrin activation pathways for effector and regulatory T cell trafficking and function.J Exp Med2021
33026068Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity.Inflamm Bowel Dis2021
34720087Skin inflammation activates intestinal stromal fibroblasts and promotes colitis.J Clin Invest2021
34720087Skin inflammation activates intestinal stromal fibroblasts and promotes colitis.J Clin Invest2021
34253728Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease.Nat Commun2021
33026068Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity.Inflamm Bowel Dis2021
33104169Distinct integrin activation pathways for effector and regulatory T cell trafficking and function.J Exp Med2021
32433949Heterogenous Populations of Tissue-Resident CD8<sup>+</sup> T Cells Are Generated in Response to Infection and Malignancy.Immunity2020
32433949Heterogenous Populations of Tissue-Resident CD8<sup>+</sup> T Cells Are Generated in Response to Infection and Malignancy.Immunity2020
32414833Early precursors and molecular determinants of tissue-resident memory CD8<sup>+</sup> T lymphocytes revealed by single-cell RNA sequencing.Sci Immunol2020
32062041Development and Validation of Clinical Scoring Tool to Predict Outcomes of Treatment With Vedolizumab in Patients With Ulcerative Colitis.Clin Gastroenterol Hepatol2020
32103176Global chemical effects of the microbiome include new bile-acid conjugations.Nature2020
32826341Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses.Sci Immunol2020
32978300Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population.Proc Natl Acad Sci U S A2020
33382932Pathophysiology of Inflammatory Bowel Diseases.N Engl J Med2020
32062041Development and Validation of Clinical Scoring Tool to Predict Outcomes of Treatment With Vedolizumab in Patients With Ulcerative Colitis.Clin Gastroenterol Hepatol2020
32103176Global chemical effects of the microbiome include new bile-acid conjugations.Nature2020
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Collaborators

Brigid S Boland
University of California
Co-authored papers 26
William J Sandborn
University of California San Diego
Co-authored papers 21
Gene W Yeo
University of California
Co-authored papers 12
Parambir S Dulai
Feinberg School of Medicine Northwestern University
Co-authored papers 11
Jocelyn G Olvera
Co-authored papers 8
Siddharth Singh
University of California San Diego
Co-authored papers 8
Mark H Ginsberg
University of California
Co-authored papers 6
Corey A Siegel
Dartmouth-Hitchcock Medical Center
Co-authored papers 5
Janilyn Arsenio
University of Manitoba
Co-authored papers 5
Pieter C Dorrestein
Co-authored papers 4
Gregory Humphrey
University of California
Co-authored papers 4
Boyko Kakaradov
Deep Genomics Inc., University Avenue
Co-authored papers 4
Samuel B Ho
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
Co-authored papers 4
Wendy Huang
Co-authored papers 4
Kathleen M Fisch
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 3
Bruce E Sands
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Jean-Frederic Colombel
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Matthew S Tsai
Co-authored papers 3
Rob Knight
University of California
Co-authored papers 3
David L Boyle
Co-authored papers 3
Edward V Loftus
Mayo Clinic College of Medicine and Science
Co-authored papers 3
Arun Swaminath
Lenox Hill Hospital
Co-authored papers 3
Eugenia Shmidt
University of Minnesota
Co-authored papers 3
James A Proudfoot
Shiley Eye Institute, University of California
Co-authored papers 3
David Hudesman
NYU Grossman School of Medicine
Co-authored papers 3
Sunanda V Kane
Mayo Clinic
Co-authored papers 3
Dana J Lukin
Jill Roberts Center for IBD
Co-authored papers 3
Mahdieh Khosroheidari
Institute for Genomic Medicine, University of California San Diego
Co-authored papers 2
Gail Ackermann
University of California San Diego
Co-authored papers 2
Huib Ovaa
Leiden University Medical Center
Co-authored papers 2
Release 1.2