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Author Details

J??rg Menche
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
2010
56
25
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36626231Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension.JCI Insight2023
37633982Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet.Sci Rep2023
37664457Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model.Front Cell Dev Biol2023
37567409Low-dose Bisphenol A exposure alters the functionality and cellular environment in a human cardiomyocyte model.Environ Pollut2023
36949045Assessment of community efforts to advance network-based prediction of protein-protein interactions.Nat Commun2023
37414142Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model.Mol Metab2023
37342957Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency.N Engl J Med2023
35022603The regulatory network architecture of cardiometabolic diseases.Nat Genet2022
35627149Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease.Genes (Basel)2022
34935929BioProfiling.jl: profiling biological perturbations with high-content imaging in single cells and heterogeneous populations.Bioinformatics2022
34233185Morphological profiling of human T and NK lymphocytes by high-content cell imaging.Cell Rep2021
33627323Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.Diabetes2021
33893283The VRNetzer platform enables interactive network analysis in Virtual Reality.Nat Commun2021
33662183Green Hydrothermal Synthesis of Fluorescent 2,3-Diarylquinoxalines and Large-Scale Computational Comparison to Existing Alternatives.ChemSusChem2021
33855809Green Hydrothermal Synthesis of Fluorescent 2,3-Diarylquinoxalines and Large-Scale Computational Comparison to Existing Alternatives.ChemSusChem2021
34589226Hydrothermal polymerization of porous aromatic polyimide networks and machine learning-assisted computational morphology evolution interpretation.J Mater Chem A Mater2021
34753928Network analysis reveals rare disease signatures across multiple levels of biological organization.Nat Commun2021
32646852The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.Sci Immunol2020
31969567Environmental arginine controls multinuclear giant cell metabolism and formation.Nat Commun2020
33199895The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages.Nat Metab2020
31133746MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.Nat Genet2019
31784108Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.Immunity2019
31723137Mapping the perturbome network of cellular perturbations.Nat Commun2019
31442425Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation.Mol Cell2019
31321300HACE1 deficiency leads to structural and functional neurodevelopmental defects.Neurol Genet2019
31427792Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers.Nat Genet2019
31064751Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms.Blood2019
29423274A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.NPJ Syst Biol Appl2018
29891926Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.Nat Commun2018
29858401B Cell-Activating Factor Neutralization Aggravates Atherosclerosis.Circulation2018
29932108Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology.Pharmaceuticals (Basel)2018
29959183Non-classical monocytes as mediators of tissue destruction in arthritis.Ann Rheum Dis2018
29977601Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.NPJ Syst Biol Appl2018
30262855Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module.Sci Rep2018
28899006Network medicine: a new paradigm for cardiovascular disease research and beyond.Cardiovasc Res2017
28418389The immune system as a social network.Nat Immunol2017
29261807Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.PLoS Pathog2017
29089570Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.Nat Commun2017
28649437Integrating personalized gene expression profiles into predictive disease-associated gene pools.NPJ Syst Biol Appl2017
28530711A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.Nat Chem Biol2017
27107014An inter-species protein-protein interaction network across vast evolutionary distance.Mol Syst Biol2016
28185567From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration.BMC Bioinformatics2016
27748412Tissue Specificity of Human Disease Module.Sci Rep2016
27278246Endophenotype Network Models: Common Core of Complex Diseases.Sci Rep2016
26831545Network-based in silico drug efficacy screening.Nat Commun2016
25586491A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.Hum Mol Genet2015
26571460Canonical genetic signatures of the adult human brain.Nat Neurosci2015
25853560A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome.PLoS Comput Biol2015
25700523Disease networks. Uncovering disease-disease relationships through the incomplete interactome.Science2015
24967666Human symptoms-disease network.Nat Commun2014
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Collaborators

Albert-L??szl?? Barab??si
Network Science Institute, Northeastern University
Co-authored papers 18
Christoph Bock
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 7
Stefan Kubicek
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 6
Marc Vidal
Blavatnik Institute, Harvard Medical School
Co-authored papers 6
Michael Schuster
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 5
Edwin K Silverman
Brigham and Women's Hospital
Co-authored papers 5
Joanna I Loizou
Center for Cancer Research, Comprehensive Cancer Centre, Medical University of Vienna
Co-authored papers 4
Fiorella Schischlik
National Cancer Institute, National Institutes of Health
Co-authored papers 3
Robert Kralovics
Medical University of Vienna
Co-authored papers 3
Lydia Robinson-Garcia
CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Scott T Weiss
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Radu Dobrin
Janssen Research & Development Inc.
Co-authored papers 2
Kerstin Spirohn
Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute
Co-authored papers 2
Martin Moder
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Frederick P Roth
University of Toronto
Co-authored papers 2
Michael H Cho
Brigham and Women's Hospital Channing Division of Network Medicine
Co-authored papers 2
Patrick Aloy
Institucio Catalana de Recerca i Estudis Avancats (ICREA)
Co-authored papers 2
David Gomez-Cabrero
King Abdullah University of Science and Technology
Co-authored papers 2
Georgia Velimezi
University of Patras
Co-authored papers 2
Christian Schmidl
Leibniz Institute for Immunotherapy
Co-authored papers 2
Natali Gulbahce
Complete Genomics Inc.
Co-authored papers 2
Michel Owusu
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Joana Ferreira da Silva
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
John J O'Shea
National Institute of Arthritis, National Institutes of Health
Co-authored papers 2
Andr?? F Rendeiro
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Marc Wiedner
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Co-authored papers 2
Nidhi Sahni
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Yu Xia
College of Information Engineering, Zhejiang University of Technology
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Jesper Tegn??r
King Abdullah University of Science and Technology (KAUST)
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Stephen P Jackson
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