Author details

Full Name

Michael Chong

Affiliation

ORCID

Career Start Year

2013

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36917778	Vascular-Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling.	Am J Respir Crit Care Med	2023
36300369	Anti-Epileptic Drug Target Perturbation and Intracranial Aneurysm Risk: Mendelian Randomization and Colocalization Study.	Stroke	2023
37626057	A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets.		2023
36894711	Identifying individuals at extreme risk of venous thromboembolism using polygenic risk scores.		2023
36548480	Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Studyâ¿ .	Circ Genom Precis Med	2023
37498601	Biomarkers Associated With Severe COVID-19 Among Populations With High Cardiometabolic Risk: A 2-Sample Mendelian Randomization Study.		2023
35197325	Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease.	J Am Soc Nephrol	2022
36240095	Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.	Neurology	2022
36360312	Evaluation of DNA Methylation Array for Glioma Tumor Profiling and Description of a Novel Epi-Signature to Distinguish IDH1/IDH2 Mutant and Wild-Type Tumors.	Genes (Basel)	2022
35446786	Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases.	JCI Insight	2022
35953142	Reply: Lipoprotein(a) and AtrialÂ Fibrillation.	Journal of the American College of Cardiology	2022
35812273	ACLY and CKD: A Mendelian Randomization Analysis.	Kidney International Reports	2022
35300815	Lipoprotein(a) Cholesterol Masquerading as Low-Density Lipoprotein Cholesterol: Catch Me if You Can.	Journal of the American College of Cardiology	2022
35023831	GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia.	eLife	2022
34880091	Mitochondrial DNA Copy Number as a Marker and Mediator of Stroke Prognosis: Observational and Mendelian Randomization Analyses.	Neurology	2022
34615865	Calibrated rare variant genetic risk scores for complex disease prediction using large exome sequence repositories.	Nature Communications	2021
33528103	Whole exome sequencing reveals a biallelic frameshift mutation in GRXCR2 in hearing impairment in Cameroon.	Mol Genet Genomic Med	2021
34106200	Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study.	JAMA Cardiol	2021
31391289	Hypolipidaemia among patients with PMM2-CDG is associated with low circulating PCSK9 levels: a case report followed by observational and experimental studies.	Journal of Medical Genetics	2020
32019855	ACE and Type 2 Diabetes Risk: A Mendelian Randomization Study.	Diabetes Care	2020
32106772	Global Assessment of Mendelian Stroke Genetic Prevalence in 101 635 Individuals From 7 Ethnic Groups.	Stroke	2020
31928076	Identification of Circulating Proteins Associated With Blood Pressure Using Mendelian Randomization.	Circulation. Genomic and precision medicine	2020
32693751	Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.	Stroke	2020
32685888	Bleeding risks for uncharacterized platelet function disorders.	Res Pract Thromb Haemost	2020
33010842	Plasma ACE2 and risk of death or cardiometabolic diseases: a case-cohort analysis.	Lancet, The	2020
33063668	Effects of lifelong testosterone exposure on health and disease using Mendelian randomization.	eLife	2020
32842921	Beyond the Brain: Systematic Review of Extracerebral Phenotypes Associated With Monogenic Cerebral Small Vessel Disease.	Stroke	2020
31208196	Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome.	Circulation	2019
30615506	Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis.	Circulation	2019
31235487	Identification of Novel Causal Blood Biomarkers Linking Metabolically Favorable Adiposity With Type 2 Diabetes Risk.	Diabetes Care	2019
29335331	Cerebrovascular Disease Knowledge Portal: An Open-Access Data Resource to Accelerate Genomic Discoveries in Stroke.	Stroke	2018
30012324	Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease.	Journal of the American College of Cardiology	2018
29874178	Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease.	Circulation. Genomic and precision medicine	2018
30535086	Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies.	Am J Clin Nutr	2018
29531354	Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.	Nat Genet	2018
27908689	PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.	Lancet Diabetes Endocrinol	2017
28954878	<i>COL4A2</i> is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls.	Neurology	2017
28502497	The 9p21.3 locus and cardiovascular risk in familial hypercholesterolemia.	Journal of Clinical Lipidology	2017
28679849	Mendelian Genes and Risk of Intracerebral Hemorrhage and Small-Vessel Ischemic Stroke in Sporadic Cases.	Stroke	2017
28456682	Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia.	Journal of Clinical Lipidology	2017
28280076	Identification of Cadherin 2 (<i>CDH2</i>) Mutations in Arrhythmogenic Right Ventricular Cardiomyopathy.	Circ Cardiovasc Genet	2017
28181366	Molecular phenotype and bleeding risks of an inherited platelet disorder in a family with a RUNX1 frameshift mutation.	Haemophilia	2017
27678447	Frameshift mutation in the APOA5 gene causing hypertriglyceridemia in a Pakistani family: Management and considerations for cardiovascular risk.	Journal of Clinical Lipidology	2016
22999193	Genetic markers of inflammation and their role in cardiovascular disease.	Canadian Journal of Cardiology	2013