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Author Details

Aaron Isaacs
2004
144
59
PMIDPaper TitleJournal TitlePublished Year
35625889Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77.Biomedicines2022
34777816Considerations for the Assessment of Substrates, Genetics and Risk Factors in Patients with Atrial Fibrillation.Arrhythmia and Electrophysiology Review2021
34198338Clinical and electrophysiological predictors of device-detected new-onset atrial fibrillation during 3 years after cardiac surgery.Europace2021
33558525Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nat Commun2021
33506376Reappraisal of Atrial fibrillation: interaction between hyperCoagulability, Electrical remodelling and Vascular destabilisation in the progression of AF (RACE V) Tissue Bank Project: study design.Netherlands Heart Journal2021
33713866Leukocyte gene expression in post-thrombotic syndrome.Thrombosis Research2021
33555020Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference.Europace2021
33402679Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nat Commun2021
32822252Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation.Circ Genom Precis Med2020
31713012Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality.Diabetologia2020
32439900Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.Nat Commun2020
33208780JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling.Scientific Reports2020
31197173An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.Nat Commun2019
30976747Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease.Hepatology Communications2019
31263163Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals.Sci Rep2019
29506515A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy.BMC Med Genomics2018
28719597Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.Pharmacogenomics J2018
30510157GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.Nat Commun2018
30390057Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.Nat Genet2018
30012220Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.Genome Biol2018
29874175ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals.Circ Genom Precis Med2018
30046033PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.Nat Commun2018
29748316Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.Circ Genom Precis Med2018
28117334A systematic SNP selection approach to identify mechanisms underlying disease aetiology: linking height to post-menopausal breast and colorectal cancer risk.Scientific Reports2017
28379579Discovery of novel heart rate-associated loci using the Exome Chip.Hum Mol Genet2017
28794112Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.Circ Cardiovasc Genet2017
28782696Heritability in a SCN5A-mutation founder population with increased female susceptibility to non-nocturnal ventricular tachyarrhythmia and sudden cardiac death.Heart Rhythm2017
28002404Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.Nature2017
28157516PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease.Gastroenterology2017
27918535Disease variants alter transcription factor levels and methylation of their binding sites.Nat Genet2017
27918533Identification of context-dependent expression quantitative trait loci in whole blood.Nat Genet2017
27872105Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.Circ Cardiovasc Genet2016
27142678Genetic variants in RBFOX3 are associated with sleep latency.Eur J Hum Genet2016
26833098Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.Nat Commun2016
26962151Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram.Hum Mol Genet2016
27329260Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.Aging Cell2016
26831199Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Nat Commun2016
26997408Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.Psychol Med2016
26860063Association of the IGF1 gene with fasting insulin levels.Eur J Hum Genet2016
27036123Meta-analysis of 49â¿¿549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.J Med Genet2016
26898941Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs.J Autoimmun2016
26653072Discriminative Ability of Plasma Branched-Chain Amino Acid Levels for Glucose Intolerance in Families At Risk for Type 2 Diabetes.Metab Syndr Relat Disord2016
27577874Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans.Hum Mol Genet2016
2765946652 Genetic Loci Influencing Myocardial Mass.J Am Coll Cardiol2016
27877193A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study.Front Genet2016
27876822A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.Nat Commun2016
24791963Failing beta-cell adaptation in South Asian families with a high risk of type 2 diabetes.Acta Diabetol2015
28721259Fine mapping the <i>CETP</i> region reveals a common intronic insertion associated to HDL-C.NPJ Aging Mech Dis2015
25673413Genetic studies of body mass index yield new insights for obesity biology.Nature2015
25751400Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels.Nat Commun2015
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University of Oxford
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Erasmus University Medical Center
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Harvard T.H. Chan School of Public Health
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University Medical Center Rotterdam
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National Institute on Aging
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University of Michigan School of Public Health ann arbor
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King's College London
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Finnish Cardiovascular Research Center-Tampere - FCRCT, Tampere University
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Institute for Biomedicine, Affiliated institute of the University of Lubeck
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Baylor College of Medicine
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German Research Center for Cardiovascular Disease (DZHK)
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National Institute on Aging, National Institutes of Health
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