Author details

Full Name

Colin A McKenzie

Affiliation

ORCID

Career Start Year

1995

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
31857576	Edematous severe acute malnutrition is characterized by hypomethylation of DNA.	Nat Commun	2019
29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Am J Hum Genet	2018
30120022	Exploring putative genetic determinants of inter-individual phenotypic heterogeneity in sickle cell disease: A cross-sectional Jamaican cohort-based study.	Blood Cells, Molecules, and Diseases	2018
29912962	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.	PLoS One	2018
29750786	Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.	PLoS Genet	2018
29114966	A cross-sectional clinic-based study exploring whether variants within the glutathione S-transferase, haptoglobin and uridine 5'-diphospho-glucuronosyltransferase 1A1 genes are associated with interindividual phenotypic variation in sickle cell anaemia in	European Journal of Haematology	2018
28218758	Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.	Nat Genet	2017
28498854	Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.	PLoS Genet	2017
28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Nat Commun	2017
27618452	The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.	Nat Genet	2016
26833246	New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.	Nat Commun	2016
27036123	Meta-analysis of 49â¿¿549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.	J Med Genet	2016
25673412	New genetic loci link adipose and insulin biology to body fat distribution.	Nature	2015
25673413	Genetic studies of body mass index yield new insights for obesity biology.	Nature	2015
25161768	Vitamin D levels are low in adult patients with sickle cell disease in Jamaica and West Africa.	BMC Hematol	2014
25282103	Defining the role of common variation in the genomic and biological architecture of adult human height.	Nat Genet	2014
24564034	Prevalence of overweight and obesity among children six to ten years of age in the north-east health region of Jamaica.	West Indian Medical Journal	2013
22956460	Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians.	Int Urol Nephrol	2013
23937567	Quantitative variation in plasma angiotensin-I converting enzyme activity shows allelic heterogeneity in the ABO blood group locus.	Annals of Human Genetics	2013
24097068	Discovery and refinement of loci associated with lipid levels.	Nat Genet	2013
24097064	Common variants associated with plasma triglycerides and risk for coronary artery disease.	Nat Genet	2013
21593783	Patterns of sodium and potassium excretion and blood pressure in the African Diaspora.	J Hum Hypertens	2012
21942117	The predictive value of urinary vanillylmandelic acid testing in the diagnosis of phaeochromocytoma at the University Hospital of the West Indies.	West Indian Medical Journal	2011
21347282	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	PLoS Genet	2011
21262107	A preliminary examination of the effects of genetic variants of redox enzymes on susceptibility to oedematous malnutrition and on percentage cytotoxicity in response to oxidative stress in vitro.		2011
21424828	The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA.	Hum Genet	2011
21909115	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.	Nature	2011
20400458	Genome-wide association of anthropometric traits in African- and African-derived populations.	Hum Mol Genet	2010
20839009	Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.	Hum Genet	2010
20221249	Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples.	PLoS Genet	2010
20430937	Fine mapping of the association with obesity at the FTO locus in African-derived populations.	Hum Mol Genet	2010
19148297	Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients.	PLoS One	2009
19120354	Ethnic differences in F cell levels in Jamaica: a potential tool for identifying new genetic loci controlling fetal haemoglobin.	Br J Haematol	2009
19664003	Rate of change of sickle allele frequency may be influenced by total fertility rate: a sesquicentenary reflection on human micro-evolution.	Br J Haematol	2009
18544166	A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene.	BMC Med Genomics	2008
18072409	Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism.	West Indian Medical Journal	2007
17688704	Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations.	BMC Genet	2007
17381963	Childhood malnutrition is associated with a reduction in the total melanin content of scalp hair.	Br J Nutr	2007
16709328	Polymorphisms in genes involved in folate metabolism as risk factors for oedematous severe childhood malnutrition: a hypothesis-generating study.		2006
16923217	Glutathione S-transferase polymorphisms may be associated with risk of oedematous severe childhood malnutrition.	British Journal of Nutrition	2006
16432044	Epithelial sodium channel allele T594M is not associated with blood pressure or blood pressure response to amiloride.	Hypertension	2006
16929536	Predicted declines in sickle allele frequency in Jamaica using empirical data.	Am J Hematol	2006
15919834	Angiotensin-converting enzyme gene polymorphisms and obesity: an examination of three black populations.	Obes Res	2005
15720304	SNP haplotypes in the angiotensin I-converting enzyme (ACE) gene: analysis of Nigerian family data using gamete competition models.	Ann Hum Genet	2005
16156863	The frequency of the sickle allele in Jamaica has not declined over the last 22 years.	Br J Haematol	2005
15388579	UGT1A1 variation and gallstone formation in sickle cell disease.	Blood	2005
15199718	HIV serostatus and recovery from severe childhood malnutrition. A retrospective matched case-control study.	West Indian Medical Journal	2004
15256516	Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk.	Int J Epidemiol	2004