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Author Details

Yuhua Xue
School of Pharmaceutical Sciences, Xiamen University
2008
51
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37476050Decellularized squid mantle scaffolds as tissue-engineered corneal stroma for promoting corneal regeneration.Bioeng Transl Med2023
37619669Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction.Ocul Surf2023
37540094Quantitative Proteomics of the CDK9 Interactome Reveals a Function of the HSP90-CDC37-P-TEFb Complex for BETi-Induced HIV-1 Latency Reactivation.J Proteome Res2023
37016511Isobaric Stable Isotope N-Phosphorylation Labeling (iSIPL) for Ultrasensitive Proteome Quantification.Angew Chem Int Ed Engl2023
35178129Polyphenol Extracts from Grape Seeds and Apple Can Reactivate Latent HIV-1 Transcription through Promoting P-TEFb Release from 7SK snRNP.Dis Markers2022
35393539Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage.Nat Cell Biol2022
36177466Receptor-binding domain-anchored peptides block binding of severe acute respiratory syndrome coronavirus 2 spike proteins with cell surface angiotensin-converting enzyme 2.Front Microbiol2022
35878206Phenotypic and Transcriptomics Analyses Reveal Underlying Mechanisms in a Mouse Model of Corneal Bee Sting.Toxins (Basel)2022
35307497Polystyrene microplastic particles: In vivo and in vitro ocular surface toxicity assessment.Environ Pollut2022
33461468Resveratrol Promotes HIV-1 Tat Accumulation via AKT/FOXO1 Signaling Axis and Potentiates Vorinostat to Antagonize HIV-1 Latency.Curr HIV Res2021
35072011A natural product targets BRD4 to inhibit phase separation and gene transcription.iScience2021
34738709Synthesis and Antiproliferative Activity of New Thiosemicarboxamide Derivatives.Chem Biodivers2021
34411762Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.J Proteomics2021
34277619Novel Cell Culture Paradigm Prolongs Mouse Corneal Epithelial Cell Proliferative Activity <i>in vitro</i> and <i>in vivo</i>.Front Cell Dev Biol2021
34324861Real-time confocal microscopy imaging of corneal cytoarchitectural changes induced by different stresses.Exp Eye Res2021
34147784Phenotypic and transcriptomic changes in the corneal epithelium following exposure to cigarette smoke.Environ Pollut2021
34229558Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1<i>H</i>-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent.J Enzyme Inhib Med Chem2021
32479599Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2.Nucleic Acids Res2020
32087315ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation.Biochim Biophys Acta Gene Regul Mech2020
32048991JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.Elife2020
32044517Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.Bioorg Chem2020
32653610Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors.Bioorg Chem2020
32548957Onion Epithelial Membrane Scaffolds Transfer Corneal Epithelial Layers in Reconstruction Surgery.Adv Healthc Mater2020
32292346Protective Effects Oncorneal Endothelium During Intracameral Irrigation Using N-(2)-l-alanyl-l-Glutamine.Front Pharmacol2020
32128251Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription.Cell Discov2020
30973208The role of autophagy in the pathogenesis of exposure keratitis.J Cell Mol Med2019
30864669A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis.Nucleic Acids Res2019
30125539Epithelial dysplasia in pterygium postoperative granuloma.Exp Eye Res2018
35539279Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1.RSC Adv2018
28878233A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter.Sci Rep2017
28178646Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells.Oncotarget2017
28595723Stable isotope N-phosphoryl amino acids labeling for quantitative profiling of amine-containing metabolites using liquid chromatography mass spectrometry.Anal Chim Acta2017
27315790Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents.Chem Biol Drug Des2016
26007649Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.Nucleic Acids Res2015
26569506A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP.PLoS One2015
26186095Correction: Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism.Elife2015
24367103AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.Proc Natl Acad Sci U S A2014
24793763Mechanism and factors that control HIV-1 transcription and latency activation.J Zhejiang Univ Sci B2014
24634865Fibrin glue-assisted for the treatment of corneal perforations using glycerin-cryopreserved corneal tissue.Int J Ophthalmol2014
23739874Hypoxia affects in vitro proliferation and differentiation of mouse corneal epithelial progenitor cell.In Vitro Cell Dev Biol Anim2013
23795863Viral-host interactions that control HIV-1 transcriptional elongation.Chem Rev2013
22253435Mutual information analysis reveals coevolving residues in Tat that compensate for two distinct functions in HIV-1 gene expression.J Biol Chem2012
21219541Downregulation of HTPAP transcript variant 1 correlates with tumor metastasis and poor survival in patients with hepatocellular carcinoma.Cancer Sci2011
21873227Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.Proc Natl Acad Sci U S A2011
21586224[High expression of thrombin receptor PAR1 in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma in early stage].Zhonghua Gan Zang Bing Za Zhi2011
19906723A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.Nucleic Acids Res2010
20890897Thrombin is a therapeutic target for metastatic osteopontin-positive hepatocellular carcinoma.Hepatology2010
20942864Human mesenchymal stem cells inhibit metastasis of a hepatocellular carcinoma model using the MHCC97-H cell line.Cancer Sci2010
20471948HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.Mol Cell2010
20345480Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection.Cancer Sci2010
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Collaborators

Qiang Zhou
The University of Hong Kong
Co-authored papers 18
Huasong Lu
Life Sciences Institute, Zhejiang University
Co-authored papers 7
Min Liu
Xiamen University
Co-authored papers 3
Zichong Li
Gladstone Center for HIV Cure Research, Gladstone Institute of Virology
Co-authored papers 3
Tom Alber
University of California berkeley
Co-authored papers 3
Nanhai He
Adlai Nortye USA Inc.
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Seemay Chou
University of California - San Francisco
Co-authored papers 2
Ursula Schulze-Gahmen
Gladstone Institute of Virology, Gladstone Institutes San Francisco CA USA .
Co-authored papers 2
Adam P Arkin
Lawrence Berkeley National Laboratory
Co-authored papers 1
Zhiyuan Yang
Gladstone Institute of Virology and Immunology
Co-authored papers 1
Guan Wang
Jilin University
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
John C Burnett
Mayo Clinic
Co-authored papers 1
Gregory D Friedland
Joint BioEnergy Institute
Co-authored papers 1
David V Schaffer
University of California berkeley
Co-authored papers 1
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Ben Weisburd
Broad Institute of MIT and Harvard
Co-authored papers 1
Siddharth S Dey
University of California Santa Barbara
Co-authored papers 1
Joanne H Hsu
Clinical Research Division, Fred Hutchinson Cancer Research Center
Co-authored papers 1
Marcin P Joachimiak
E O Lawrence Berkeley National Laboratory, UCSF Medical Center, University of California, Berkeley, University of Chicago
Co-authored papers 1
Alma L Burlingame
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Guoying K Yu
Co-authored papers 1
Release 1.2