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Author Details

Heiko S Schadt
Novartis Institutes for BioMedical Research, Novartis Pharma AG
2007
12
8
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36410420Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.Am J Pathol2023
36473578Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes.Toxicol In Vitro2023
34326236Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2.Science2021
33791693Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2.bioRxiv2021
32930584Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4.J Med Chem2020
31409633FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer.Mol Cancer Ther2019
29432567Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation.Toxicol Sci2018
26874804Bile acids in drug induced liver injury: Key players and surrogate markers.Clin Res Hepatol Gastroenterol2016
27576608Ocular toxicity of AUY922 in pigmented and albino rats.Toxicol Appl Pharmacol2016
23175984Quantification of vitamin D3 in feed, food, and pharmaceuticals using high-performance liquid chromatography/tandem mass spectrometry.J AOAC Int2012
192752582-Amino-2-deoxyisochorismate is a key intermediate in Bacillus subtilis p-aminobenzoic acid biosynthesis.J Am Chem Soc2009
17886307Action of atrop-abyssomicin C as an inhibitor of 4-amino-4-deoxychorismate synthase PabB.Angew Chem Int Ed Engl2007
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Collaborators

Audrey Fischer
Department of Preclinical Safety, Novartis Institutes for BioMedical Research
Co-authored papers 4
Francois Pognan
Novartis
Co-authored papers 4
Philippe Couttet
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Olivier Schwartz
Institut Pasteur, Universite Paris Cite, CNRS UMR9
Co-authored papers 2
Veronica V Rezelj
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Matthew J O'Meara
University of Michigan ann arbor
Co-authored papers 2
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Thomas Vallet
Institut Pasteur, Center for the Viral Populations and Pathogenesis
Co-authored papers 2
Jiankun Lyu
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Andrew C Kruse
Blavatnik Institute, Harvard Medical School
Co-authored papers 2
Blandine Monel
Institut Pasteur, CNRS UMR 3569
Co-authored papers 2
Brian K Shoichet
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Laszlo Urban
Matrahaza University and Teaching Hospital
Co-authored papers 2
Assaf Alon
Harvard Medical School
Co-authored papers 2
Kevan M Shokat
University of California San Francisco
Co-authored papers 2
Tia A Tummino
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 2
Marco Vignuzzi
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Sonia Jangra
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Ziyang Zhang
Quantitative Biosciences Institute (QBI)
Co-authored papers 1
Ziyang Zhang
Quantitative Biosciences Institute (QBI)
Co-authored papers 1
William R Sellers
Co-authored papers 1
Michael Schotsaert
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Raveen Rathnasinghe
Icahn School of Medicine at Mount Sinai New York
Co-authored papers 1
Benoit Fischer
Novartis Institutes for BioMedical Research, Preclinical Safety
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Benoit Fischer
Novartis Institutes for BioMedical Research, Preclinical Safety
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Briana L McGovern
Icahn School of Medicine at Mount Sinai
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Henry R O'Donnell
Department of Pharmaceutical Chemistry, University of California San Francisco (UCSF)
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Romel Rosales
Icahn School of Medicine at Mount Sinai
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