Author details

Full Name

Mainak Guharoy

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37464277	SNPeffect 5.0: large-scale structural phenotyping of protein coding variants extracted from next-generation sequencing data using AlphaFold models.		2023
35545699	Degron masking outlines degronons, co-degrading functional modules in the proteome.	Commun Biol	2022
32502383	Distance-Based Metrics for Comparing Conformational Ensembles of Intrinsically Disordered Proteins.	Biophys J	2020
31713636	DisProt: intrinsic protein disorder annotation in 2020.	Nucleic Acids Res	2020
30878482	The Balancing Act of Intrinsically Disordered Proteins: Enabling Functional Diversity while Minimizing Promiscuity.	J Mol Biol	2019
30212197	Unique Physicochemical Patterns of Residues in Protein-Protein Interfaces.	J Chem Inf Model	2018
30070766	Disordered Substrates of the 20S Proteasome Link Degradation with Phase Separation.	Proteomics	2018
28306503	Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.	Mol Cell	2017
26851277	Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.	J Biol Chem	2016
27385826	Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.	Proc Natl Acad Sci U S A	2016
26732515	Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.	Nat Commun	2016
26301226	Computational approaches for inferring the functions of intrinsically disordered proteins.	Front Mol Biosci	2015
25968230	DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder.	BMC Bioinformatics	2015
26439842	Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins.	PLoS One	2015
26437245	Ensemble Methods Enable a New Definition for the Solution to Gas-Phase Transfer of Intrinsically Disordered Proteins.	J Am Chem Soc	2015
26000490	SnapShot: Intrinsic Structural Disorder.	Cell	2015
26387106	Bioinformatics Approaches for Predicting Disordered Protein Motifs.	Adv Exp Med Biol	2015
23734257	Functional diversity and structural disorder in the human ubiquitination pathway.	PLoS One	2013
23761374	Intrinsic structural disorder in cytoskeletal proteins.	Cytoskeleton (Hoboken)	2013
23934783	Reassessing buried surface areas in protein-protein complexes.	Protein Science	2013
22641851	Characterization and prediction of the binding site in DNA-binding proteins: improvement of accuracy by combining residue composition, evolutionary conservation and structural parameters.	Nucleic Acids Research	2012
22001016	Community-wide assessment of protein-interface modeling suggests improvements to design methodology.	J Mol Biol	2011
21519818	PRICE (PRotein Interface Conservation and Energetics): a server for the analysis of protein-protein interfaces.	Journal of Structural and Functional Genomics	2011
20507585	Conserved residue clusters at protein-protein interfaces and their use in binding site identification.	BMC Bioinformatics	2010
20737439	Side-chain rotamer transitions at protein-protein interfaces.	Proteins: Structure, Function and Bioinformatics	2010
18704949	Dissection, residue conservation, and structural classification of protein-DNA interfaces.	Proteins: Structure, Function and Bioinformatics	2009
19479323	Empirical estimation of the energetic contribution of individual interface residues in structures of protein-protein complexes.	Journal of Computer-Aided Molecular Design	2009
18841236	Structural segments and residue propensities in protein-RNA interfaces: comparison with protein-protein and protein-DNA complexes.		2008
17510165	Secondary structure based analysis and classification of biological interfaces: identification of binding motifs in protein-protein interactions.		2007
16221766	Conservation and relative importance of residues across protein-protein interfaces.	Proceedings of the National Academy of Sciences of the United States of America	2005