Author details

Full Name

Charles C Gu

Affiliation

ORCID

Career Start Year

1995

Papers

121

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37046083	Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.	Nature	2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37268629	Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups.	Nat Commun	2023
37126548	The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.	Sci Adv	2023
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
36544485	Multi-omics insights into the biological mechanisms underlying statistical gene-by-lifestyle interactions with smoking and alcohol consumption.	Front Genet	2022
33416449	Donor-specific phenotypic variation in hiPSC cardiomyocyte-derived exosomes impacts endothelial cell function.	Am J Physiol Heart Circ Physiol	2021
33679876	Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify <i>MYRIP</i>, <i>TRAPPC11</i>, and <i>SLC27A6</i> of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population.	Front Genet	2021
30262922	Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31.	Eur J Hum Genet	2019
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
29381148	Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.	Int J Obes (Lond)	2018
29912962	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.	PLoS One	2018
29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Am J Hum Genet	2018
28993450	Blood Pressure Genetic Risk Score Predicts Blood Pressure Responses to Dietary Sodium and Potassium: The GenSalt Study (Genetic Epidemiology Network of Salt Sensitivity).	Hypertension	2017
28899353	Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation.	BMC Genomics	2017
28391526	Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.	Hum Genet	2017
28234671	Rare coding variants associated with blood pressure variation in 15â¿¿914 individuals of African ancestry.	J Hypertens	2017
28200110	Associations Between Genetic Variants of NADPH Oxidase-Related Genes and Blood Pressure Responses to Dietary Sodium Intervention: The GenSalt Study.	American Journal of Hypertension	2017
27867202	Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations.	Int J Obes (Lond)	2017
29503979	Whole exome analyses to examine the impact of rare variants on left ventricular traits in African American participants from the HyperGEN and GENOA studies.	J Hypertens Manag	2017
26582766	Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.	Circulation: Cardiovascular Genetics	2016
26582410	Common variants in the Na(+)-coupled bicarbonate transporter genes and salt sensitivity of blood pressure: the GenSalt study.	Journal of Human Hypertension	2016
26556563	Genetic association of left ventricular mass assessed by M-mode and two-dimensional echocardiography.	Journal of Hypertension	2016
26224401	Associations Between Genetic Variants of the Natriuretic Peptide System and Blood Pressure Response to Dietary Sodium Intervention: The GenSalt Study.	American Journal of Hypertension	2016
27418245	Associations of Variants in the CACNA1A and CACNA1C Genes With Longitudinal Blood Pressure Changes and Hypertension Incidence: The GenSalt Study.	American Journal of Hypertension	2016
27271309	Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study.	Hypertension	2016
25231509	Associations of epithelial sodium channel genes with blood pressure: the GenSalt study.	Journal of Human Hypertension	2015
26088064	Aggregate blood pressure responses to serial dietary sodium and potassium intervention: defining responses using independent component analysis.	BMC Genetics	2015
25819087	Genome-wide linkage and positional association analyses identify associations of novel AFF3 and NTM genes with triglycerides: the GenSalt study.	Journal of Genetics and Genomics	2015
25249183	Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.	Hum Mol Genet	2015
24658007	Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese.	PLoS ONE	2014
23695277	Random forest fishing: a novel approach to identifying organic group of risk factors in genome-wide association studies.	European Journal of Human Genetics	2014
25168954	A custom correlation coefficient (CCC) approach for fast identification of multi-SNP association patterns in genome-wide SNPs data.	Genetic Epidemiology	2014
25073833	Interplay of genetic risk (CHRNA5) and environmental risk (partner smoking) on cigarette smoking reduction.	Drug Alcohol Depend	2014
24878720	A gene-based analysis of variants in the serum/glucocorticoid regulated kinase (SGK) genes with blood pressure responses to sodium intake: the GenSalt Study.	PLoS ONE	2014
24780206	Association of comorbidity burden with abnormal cardiac mechanics: findings from the HyperGEN study.	J Am Heart Assoc	2014
24011389	The St. Louis African American health-heart study: methodology for the study of cardiovascular disease and depression in young-old African Americans.	BMC Cardiovascular Disorders	2013
23443727	Common genetic variants in the endothelial system predict blood pressure response to sodium intake: the GenSalt study.	American Journal of Hypertension	2013
23341774	A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.	PLoS Genet	2013
24165912	Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.	Circulation: Cardiovascular Genetics	2013
24114848	A whole-genome simulator capable of modeling high-order epistasis for complex disease.	Genetic Epidemiology	2013
24094743	Fine Mapping and Identification of BMI Loci in African Americans.	Am J Hum Genet	2013
22510845	Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets.	European Journal of Human Genetics	2012
23102619	Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance.		2012
22751097	Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.	Nat Genet	2012
22719818	Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition.	PLoS One	2012
22654895	Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophy.	Front Genet	2012
22644746	Genotype imputation for African Americans using data from HapMap phase II versus 1000 genomes projects.	Genet Epidemiol	2012
21151011	Five blood pressure loci identified by an updated genome-wide linkage scan: meta-analysis of the Family Blood Pressure Program.	Am J Hypertens	2011