Author details

Full Name

Mohan Somasundaran

Affiliation

University of Massachusetts Chan Medical School

ORCID

Career Start Year

1985

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36893269	Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.	Proc Natl Acad Sci U S A	2023
35045267	Identification of a Permissive Secondary Mutation That Restores the Enzymatic Activity of Oseltamivir Resistance Mutation H275Y.	J Virol	2022
37274537	Anti-SARS-CoV-2 Activity of Adamantanes In Vitro and in Animal Models of Infection.	COVID	2022
35891350	A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants.	Viruses	2022
35290796	Quantitative structural analysis of influenza virus by cryo-electron tomography and convolutional neural networks.	Structure	2022
34293929	SARS-CoV-2 Initiates Programmed Cell Death in Platelets.	Circ Res	2021
33619959	Inhibiting HTLV-1 Protease: A Viable Antiviral Target.	ACS Chem Biol	2021
33495478	Unique structural solution from a V<sub>H</sub>3-30 antibody targeting the hemagglutinin stem of influenza A viruses.	Nat Commun	2021
30381484	Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody.	J Virol	2019
29093087	Early Epstein-Barr Virus Genomic Diversity and Convergence toward the B95.8 Genome in Primary Infection.	J Virol	2018
29687407	Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues.	J Neurovirol	2018
29760455	Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.	Sci Rep	2018
29118121	HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.	J Virol	2018
28452355	Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.	Nat Commun	2017
27104621	Early Combination Antiretroviral Therapy Limits Exposure to HIV-1 Replication and Cell-Associated HIV-1 DNA Levels in Infants.	PLoS One	2016
27733645	High Epstein-Barr Virus Load and Genomic Diversity Are Associated with Generation of gp350-Specific Neutralizing Antibodies following Acute Infectious Mononucleosis.	J Virol	2016
25693029	Viremic relapse after HIV-1 remission in a perinatally infected child.	N Engl J Med	2015
26573574	Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission.	Retrovirology	2015
26416268	A Gene Expression Signature That Correlates with CD8+ T Cell Expansion in Acute EBV Infection.	J Immunol	2015
25914058	The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.	Structure	2015
24429365	Epstein-Barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluids.	J Virol	2014
23685212	Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain.	Structure	2013
22181350	First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.	ACS Chem Biol	2012
23151449	Pilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates.	Hum Vaccin Immunother	2012
22821539	Mass spectrometry tools for analysis of intermolecular interactions.	Methods Mol Biol	2012
21843318	Genotypic and functional properties of early infant HIV-1 envelopes.	Retrovirology	2011
20152150	Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.	Structure	2010
20886079	Programmed Death-1 expression on Epstein Barr virus specific CD8+ T cells varies by stage of infection, epitope specificity, and T-cell receptor usage.	PLoS One	2010
20578491	Virologic and immunologic outcomes in HIV-infected Cambodian children after 18 months of highly active antiretroviral therapy (HAART).	Southeast Asian J Trop Med Public Health	2010
19503790	Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR.	PLoS One	2009
18177249	Identification and characterization of HIV-1 CD8+ T cell escape variants with impaired fitness.	J Infect Dis	2008
18614660	Diminished human immunodeficiency virus type 1 DNA yield from dried blood spots after storage in a humid incubator at 37 degrees C compared to -20 degrees C.	J Clin Microbiol	2008
17492595	Cytomegalovirus (CMV) IE1- and pp65-specific CD8+ T cell responses broaden over time after primary CMV infection in infants.	J Infect Dis	2007
17598142	Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity.	Proteins	2007
15655773	Development and characterization of a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody that provides effective immunoprophylaxis in mice.	J Infect Dis	2005
16049331	Pneumonitis and multi-organ system disease in common marmosets (Callithrix jacchus) infected with the severe acute respiratory syndrome-associated coronavirus.	Am J Pathol	2005
15989462	Nuclear localization of HIV type 1 Vif isolated from a long-term asymptomatic individual and potential role in virus attenuation.	AIDS Res Hum Retroviruses	2005
15452268	Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.	J Virol	2004
12594286	Differential kinetics and specificity of EBV-specific CD4+ and CD8+ T cells during primary infection.	J Immunol	2003
14647384	Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.	Nature	2003
12036487	Enhanced culture method for detection of replication-competent virus in peripheral blood mononuclear cells of HIV type 1-infected individuals.	AIDS Res Hum Retroviruses	2002
12093916	Evidence for a cytopathogenicity determinant in HIV-1 Vpr.	Proc Natl Acad Sci U S A	2002
10659052	Attenuation of human immunodeficiency virus type 1 cytopathic effects by replacing a 424-bp region of envelope from a noncytopathic biological clone.	AIDS Res Hum Retroviruses	2000
10558933	Long-term nonprogressive infection with human immunodeficiency virus type 1 in a hemophilia cohort.	J Infect Dis	1999
9333151	In vitro characterization of adult primary human immunodeficiency virus type 1: demonstration of distinctive single-cell killing phenotypes in spite of similar levels of viral replication.	J Infect Dis	1997
9207357	Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes (CTL), virus load, and CD4 T cell loss: evidence supporting a protective role for CTL in vivo.	J Infect Dis	1997
9232625	Detection and differentiation of Epstein-Barr virus strains by in situ polymerase chain reaction.	Mol Cell Probes	1997
8947293	In vitro characterization of HIV type 1 biological clones from asymptomatic and symptomatic pediatric patients.	AIDS Res Hum Retroviruses	1996
7658067	Major histocompatibility complex class I-restricted cytotoxic T lymphocyte responses to Epstein-Barr virus in children.	J Infect Dis	1995
7888220	Non-syncytium-inducing HIV type 1 isolated from infected individuals replicates in MT-2 cells.	AIDS Res Hum Retroviruses	1994

1 - 50 of 62

Chi N Chan

Vaccine & Gene Therapy Institute, Oregon Health & Science University

Career Start Year 2010

Number of shared co-authors 0

Satish K Pillai

Vitalant Research Institute, USA University of California san francisco

Career Start Year 2001

Number of shared co-authors 2

Edward P Browne

University of North Carolina at Chapel Hill

Career Start Year 2000

Number of shared co-authors 1

Maudi Killian

University of California San Francisco

Career Start Year 1999

Number of shared co-authors 0

Viviana Simon

Icahn School of Medicine at Mount Sinai

Career Start Year 1997

Number of shared co-authors 3

Paul D Bieniasz

The Rockefeller University

Career Start Year 1993

Number of shared co-authors 1

Sharon R Lewin

The University of Melbourne at the Peter Doherty Institute for Infection and Immunity

Career Start Year 1993

Number of shared co-authors 1

Wei Shao

Inc., Frederick National Laboratory for Cancer Research

Career Start Year 1993

Number of shared co-authors 2

Vicente Planelles

University of Utah

Career Start Year 1991

Number of shared co-authors 2

Keith R Jerome

Fred Hutchinson Cancer Center

Career Start Year 1991

Number of shared co-authors 1

Pavel Sova

Altius Institute for Biomedical Sciences

Career Start Year 1990

Number of shared co-authors 0

Mark Connors

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Career Start Year 1990

Number of shared co-authors 2

Rafael Delgado

Instituto de Investigacion Hospital 12 de Octubre (imas12)

Career Start Year 1988

Number of shared co-authors 0

Steven G Deeks

University of California san francisco

Career Start Year 1988

Number of shared co-authors 6

Ian Frank

IF School of Medicine, University of Pennsylvania

Career Start Year 1987

Number of shared co-authors 0

Olivier Schwartz

Institut Pasteur, Universite Paris Cite, CNRS UMR9

Career Start Year 1987

Number of shared co-authors 3

Bruce D Walker

Ragon Institute of Mass General

Career Start Year 1987

Number of shared co-authors 1

Richard T Davey

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Career Start Year 1985

Number of shared co-authors 0

Stephen Raffanti

Vanderbilt University Medical Center

Career Start Year 1983

Number of shared co-authors 0

Henry Clifford Lane

Division of Clinical Research, National Institutes of Allergy and Infectious Diseases

Career Start Year 1981

Number of shared co-authors 0

Steven M Wolinsky

Northwestern University Feinberg School of Medicine

Career Start Year 1979

Number of shared co-authors 2

Robert F Siliciano

Johns Hopkins University School of Medicine

Career Start Year 1978

Number of shared co-authors 2

John Guatelli

University of California San Diego, USA VA San Diego Healthcare System

Career Start Year 1978

Number of shared co-authors 2

Jeffrey D Lifson

Frederick National Laboratory

Career Start Year 1977

Number of shared co-authors 2

Amalio Telenti

Vir Biotechnology Inc.

Career Start Year 1977

Number of shared co-authors 0

Robert F Garry

Tulane University School of Medicine

Career Start Year 1974

Number of shared co-authors 0

Joseph B Margolick

Johns Hopkins Bloomberg School of Public Health

Career Start Year 1973

Number of shared co-authors 0

Ronald Swanstrom

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill

Career Start Year 1972

Number of shared co-authors 2

Eric Hunter

Center for Family Health Research Zambia

Career Start Year 1971

Number of shared co-authors 1

Douglas D Richman

Center for AIDS Research, University of California San Diego

Career Start Year 1970

Number of shared co-authors 2

row(s) 1 - 30 of 30

Celia A Schiffer

University of Massachusetts Chan Medical School

Co-authored papers 13

Shivender M D Shandilya

University of Massachusetts Medical School

Co-authored papers 6

Hiroshi Matsuo

Frederick National Laboratory for Cancer Research

Co-authored papers 4

Manuel Garber

Co-authored papers 3

Reuben S Harris

University of Texas Health San Antonio

Co-authored papers 3

Markus-Frederik Bohn

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 3

Michael A Carpenter

University of Minnesota

Co-authored papers 2

Shan Lu

Co-authored papers 2

Ming Li

Department of Cancer Research Institute, University of South Australia

Co-authored papers 2

Akbar Ali

University of Massachusetts Chan Medical School

Co-authored papers 2

Anurag Rathore

Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center

Co-authored papers 2

Jeffrey D Jensen

Co-authored papers 2

Karin M Green

Co-authored papers 2

Barbara Tabak

Co-authored papers 2

Shixia Wang

Co-authored papers 2

Kangkang Song

University of Massachusetts Chan Medical School

Co-authored papers 1

William L Brown

University of Minnesota

Co-authored papers 1

Jeffrey R Johnson

Gladstone Institutes

Co-authored papers 1

Derek J Hook

Institute for Therapeutics Discovery and Development, University of Minnesota

Co-authored papers 1

Jeremy Luban

Co-authored papers 1

Keisuke Shindo

Graduate School of Medicine, Kyoto University

Co-authored papers 1

Mary Munson

University of Massachusetts Chan Medical School

Co-authored papers 1

Maria L Zapp

Co-authored papers 1

Brett D Anderson

University of Minnesota

Co-authored papers 1

Jane E Freedman

Vanderbilt University Medical Center

Co-authored papers 1

Daniel A Harki

University of Minnesota

Co-authored papers 1

Daniel I S Rosenbloom

Merck & Co. Inc.

Co-authored papers 1

Michael Emerman

Fred Hutchinson Cancer Center

Co-authored papers 1

Michael R Green

Co-authored papers 1

Caroline M Mitchell

Co-authored papers 1

1 - 30

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