Author details

Full Name

David S Lawrence

Affiliation

University of North Carolina

ORCID

Career Start Year

1984

Papers

150

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35353509	Assessment of Photoreleasable Linkers and Light-Capturing Antennas on a Photoresponsive Cobalamin Scaffold.	J Org Chem	2022
33532572	Light-Controlled Release of Therapeutic Proteins from Red Blood Cells.	ACS Cent Sci	2021
31834783	Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems.	ACS Synth Biol	2020
30540191	Dasatinib Is Preferentially Active in the Activated B-Cell Subtype of Diffuse Large B-Cell Lymphoma.	J Proteome Res	2019
31353802	On Command Drug Delivery via Cell-Conveyed Phototherapeutics.	Small	2019
31353320	Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases.	Cell Chem Biol	2019
31267251	Laser Light Therapy in Inflammatory, Musculoskeletal, and Autoimmune Disease.	Curr Allergy Asthma Rep	2019
31128778	Design, construction, and validation of optogenetic proteins.	Methods Enzymol	2019
31155059	Optogenetic perturbation of the biochemical pathways that control cell behavior.	Methods Enzymol	2019
31155054	Selection and optimization of enzyme reporters for chemical cytometry.	Methods Enzymol	2019
29104065	Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase.	Cell Chem Biol	2018
29671930	Optogenetics: A Primer for Chemists.	Chembiochem	2018
29628434	Cellular Cyborgs: On the Precipice of a Drug Delivery Revolution.	Cell Chem Biol	2018
29376326	Design and Application of Sensors for Chemical Cytometry.	ACS Chem Biol	2018
28267235	Red Blood Cells for Glucose-Responsive Insulin Delivery.	Adv Mater	2017
26848595	Fluorophore Assisted Photolysis of Thiolato-Cob(III)alamins.	Inorg Chem	2016
26587880	Rational Design of a Dephosphorylation-Resistant Reporter Enables Single-Cell Measurement of Tyrosine Kinase Activity.	ACS Chem Biol	2016
26636264	The Plasma Membrane as a Reservoir, Protective Shield, and Light-Triggered Launch Pad for Peptide Therapeutics.	Angew Chem Int Ed Engl	2016
27647713	An Integrated Chemical Cytometry Method: Shining a Light on Akt Activity in Single Cells.	Angew Chem Int Ed Engl	2016
27704073	Development of a protease-resistant reporter to quantify BCR-ABL activity in intact cells.	Analyst	2016
27874260	Phototriggered Secretion of Membrane Compartmentalized Bioactive Agents.	Angew Chem Int Ed Engl	2016
25347733	Multicolor monitoring of the proteasome's catalytic signature.	ACS Chem Biol	2015
26479305	Vitamin B12: a tunable, long wavelength, light-responsive platform for launching therapeutic agents.	Acc Chem Res	2015
26418181	Optogenetic apoptosis: light-triggered cell death.	Angew Chem Int Ed Engl	2015
25697508	B(12)-mediated, long wavelength photopolymerization of hydrogels.	J Am Chem Soc	2015
24285381	Tunable visible and near-IR photoactivation of light-responsive compounds by using fluorophores as light-capturing antennas.	Angew Chem Int Ed Engl	2014
25156888	Optogenetic engineering: light-directed cell motility.	Angew Chem Int Ed Engl	2014
25154925	Cell-mediated assembly of phototherapeutics.	Angew Chem Int Ed Engl	2014
24604833	Long-wavelength fluorescent reporters for monitoring protein kinase activity.	Angew Chem Int Ed Engl	2014
24716819	Measurement of protein kinase B activity in single primary human pancreatic cancer cells.	Anal Chem	2014
23339123	Monitoring of protein arginine deiminase activity by using fluorescence quenching: multicolor visualization of citrullination.	Angew Chem Int Ed Engl	2013
24069527	Direct observation of frequency modulated transcription in single cells using light activation.	Elife	2013
23904389	Lipid pools as photolabile "protecting groups": design of light-activatable bioagents.	Angew Chem Int Ed Engl	2013
23682679	Measurement of protein tyrosine phosphatase activity in single cells by capillary electrophoresis.	Anal Chem	2013
23778327	A broad spectrum dark quencher: construction of multiple colour protease and photolytic sensors.	Chem Commun (Camb)	2013
23410952	Probes of the mitochondrial cAMP-dependent protein kinase.	Biochim Biophys Acta	2013
22385295	Proteolytic regulation of the mitochondrial cAMP-dependent protein kinase.	Biochemistry	2012
22956133	A combinatorial strategy for the acquisition of potent and specific protein tyrosine phosphatase inhibitors.	Methods Mol Biol	2012
23145001	SRC kinase regulation in progressively invasive cancer.	PLoS One	2012
22740297	Merging of confocal and caging technologies: selective three-color communication with profluorescent reporters.	Angew Chem Int Ed Engl	2012
22881604	Development of a peptidase-resistant substrate for single-cell measurement of protein kinase B activation.	Anal Chem	2012
22314840	Metabolism of peptide reporters in cell lysates and single cells.	Analyst	2012
21275391	A new trick (hydroxyl radical generation) for an old vitamin (B12).	J Am Chem Soc	2011
21302921	Construction of a photoactivatable profluorescent enzyme via propinquity labeling.	J Am Chem Soc	2011
21218856	Dual wavelength photoactivation of cAMP- and cGMP-dependent protein kinase signaling pathways.	ACS Chem Biol	2011
19765679	Light-mediated remote control of signaling pathways.	Biochim Biophys Acta	2010
20583816	Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia.	ACS Chem Biol	2010
20380406	Suborganelle sensing of mitochondrial cAMP-dependent protein kinase activity.	J Am Chem Soc	2010
20078037	Simultaneous fluorescent monitoring of proteasomal subunit catalysis.	J Am Chem Soc	2010
20073458	Light-mediated spatial control via photolabile fluorescently quenched peptide cassettes.	J Am Chem Soc	2010

1 - 50 of 150

Amit Choudhary

Broad Institute of MIT and Harvard

Career Start Year 2009

Number of shared co-authors 0

Farid El Oualid

The Netherlands Cancer Institute

Career Start Year 2004

Number of shared co-authors 0

Luke L Lairson

The Scripps Research Institute

Career Start Year 2003

Number of shared co-authors 0

Hyunil Jo

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2002

Number of shared co-authors 1

Huib Ovaa

Leiden University Medical Center

Career Start Year 2002

Number of shared co-authors 0

Craig J Thomas

Center for Cancer Research, National Cancer Institute

Career Start Year 2001

Number of shared co-authors 0

Jack Taunton

University of California san francisco

Career Start Year 1996

Number of shared co-authors 1

Paul J Hergenrother

University of Illinois at Urbana-Champaign

Career Start Year 1995

Number of shared co-authors 0

Tom W Muir

Princeton University

Career Start Year 1993

Number of shared co-authors 1

Michael J Romanowski

Sunesis Pharmaceuticals, Inc. 395 Oyster Point Boulevard

Career Start Year 1993

Number of shared co-authors 3

Eduard Sergienko

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1992

Number of shared co-authors 0

Marc Ferrer

National Institutes of Health, National Center for Advancing Translational Sciences

Career Start Year 1992

Number of shared co-authors 0

Dale J Christensen

TFF Pharmaceuticals, Inc.

Career Start Year 1992

Number of shared co-authors 0

Charles E Lyons

Massey Cancer Center, Virginia Commonwealth University

Career Start Year 1992

Number of shared co-authors 0

Michael A Whitney

University of California San Diego

Career Start Year 1990

Number of shared co-authors 1

Philip A Cole

Brigham and Women's Hospital, Blavatnik Institute, Harvard Medical School

Career Start Year 1990

Number of shared co-authors 1

Timothy A Lewis

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Career Start Year 1990

Number of shared co-authors 1

Yue-Ming Li

Memorial Sloan Kettering Cancer Center

Career Start Year 1990

Number of shared co-authors 0

John Rush

Cell Signaling Technology Inc.

Career Start Year 1987

Number of shared co-authors 0

Kevan M Shokat

University of California San Francisco

Career Start Year 1987

Number of shared co-authors 1

Rob Hooft van Huijsduijnen

Vrije Universiteit Amsterdam (VU)

Career Start Year 1987

Number of shared co-authors 0

Stuart L Schreiber

Broad Institute

Career Start Year 1985

Number of shared co-authors 1

Jill Meisenhelder

Salk Institute

Career Start Year 1984

Number of shared co-authors 0

Stefan Knapp

Institute of Pharmaceutical Chemistry, Goethe University

Career Start Year 1983

Number of shared co-authors 10

Ronald T Raines

Massachusetts Institute of Technology

Career Start Year 1981

Number of shared co-authors 0

Jonathan A Pachter

Laufer Center for Physical and Quantitative Biology, Stony Brook University

Career Start Year 1979

Number of shared co-authors 0

James A Wells

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 1974

Number of shared co-authors 1

Jack E Dixon

University of California

Career Start Year 1972

Number of shared co-authors 3

Susan S Taylor

University of California

Career Start Year 1969

Number of shared co-authors 3

Tony Hunter

Salk Institute for Biological Studies

Career Start Year 1968

Number of shared co-authors 1

row(s) 1 - 30 of 30

Zhong-Yin Zhang

Center for Cancer Research, and Institute for Drug Discovery, Purdue University

Co-authored papers 22

Sean Cahill

The Fenway Institute

Co-authored papers 4

Steven C Almo

Albert Einstein College of Medicine

Co-authored papers 4

Anne R Bresnick

Albert Einstein College of Medicine

Co-authored papers 3

Mousumi Ghosh

Co-authored papers 2

Laura E Herring

Co-authored papers 2

Robert H Singer

Albert Einstein College of Medicine

Co-authored papers 2

Desigan Kumaran

Brookhaven National Laboratory

Co-authored papers 1

Jin-Peng Sun

Co-authored papers 1

Andras Fiser

Albert Einstein College of Medicine

Co-authored papers 1

Stephen K Burley

The State University of New Jersey

Co-authored papers 1

Ragumani Sugadev

Defence Institute of Physiology and Allied Sciences (DIPAS)

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Joana Faber-Barata

Faculdade de Farmacia, Universidade Federal do Rio de Janeiro

Co-authored papers 1

Vladimir N Malashkevich

Albert Einstein College of Medicine

Co-authored papers 1

J S Emtage

Co-authored papers 1

Jeffrey B Bonanno

Albert Einstein College of Medicine

Co-authored papers 1

J Michael Sauder

Eli Lilly and Co.

Co-authored papers 1

Rakhi Agarwal

National Forensic Sciences University

Co-authored papers 1

Madegowda Mahendra

University of Mysore

Co-authored papers 1

John J Alvarado

University of Pittsburgh

Co-authored papers 1

Antonio L Amelio

University of North Carolina at Chapel Hill

Co-authored papers 1

Subramaniam Eswaramoorthy

Brookhaven National Laboratory

Co-authored papers 1

Joseph A Adams

University of California San Diego

Co-authored papers 1

Jerrold M Olefsky

University of California

Co-authored papers 1

Subramanyam Swaminathan

Brookhaven National Laboratory

Co-authored papers 1

John B Buse

University of North Carolina

Co-authored papers 1

Yury Patskovsky

New York University Grossman School of Medicine

Co-authored papers 1

Stephen R Wasserman

Argonne National Laboratory

Co-authored papers 1

Robert D Hawkins

Co-authored papers 1

1 - 30

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