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Author Details

Andrew B Waight
Merck & Co.
2003
20
12
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35727687Codon Optimization Using a Recurrent Neural Network.J Comput Biol2023
37610144A machine learning strategy for the identification of key <i>in silico</i> descriptors and prediction models for IgG monoclonal antibody developability properties.MAbs2023
35133949BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning.MAbs2022
35076451Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability.Antibodies (Basel)2022
35240221ACE2-Fc fusion protein overcomes viral escape by potently neutralizing SARS-CoV-2 variants of concern.Antiviral Res2022
33369163Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation.ChemMedChem2021
33288628Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux-positive Tumor Models.Mol Cancer Ther2021
32527543Structure-activity relationships of tubulysin analogues.Bioorg Med Chem Lett2020
30242091Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody-Drug Conjugates.Mol Cancer Ther2018
29866744Glucuronide-Linked Antibody-Tubulysin Conjugates Display Activity in MDR<sup>+</sup> and Heterogeneous Tumor Models.Mol Cancer Ther2018
26944920Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates.Mol Cancer Ther2016
27395016Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation.J Mol Biol2016
27518442Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.PLoS One2016
27078104Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.Proc Natl Acad Sci U S A2016
25187564A previously undescribed tubulin binder.Proc Natl Acad Sci U S A2014
23542591Crystal structure of a eukaryotic phosphate transporter.Nature2013
23685453Structural basis for alternating access of a eukaryotic calcium/proton exchanger.Nature2013
23773802Ion selectivity and gating mechanisms of FNT channels.Curr Opin Struct Biol2013
20010838Structure and mechanism of a pentameric formate channel.Nat Struct Mol Biol2010
12733877Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering.J Am Chem Soc2003
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Collaborators

Bj??rn Panyella Pedersen
Aarhus University
Co-authored papers 3
Robert M Stroud
University of California San Francisco
Co-authored papers 3
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Massimiliano Bonomi
Institut Pasteur, Universite Paris Cite, CNRS UMR 8
Co-authored papers 2
Bryant H Chau
Co-authored papers 2
Aaron J Risenmay
Co-authored papers 2
Avner Schlessinger
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Zygy Roe-Zurz
Pfizer Inc.
Co-authored papers 2
William Harries
University of California san francisco
Co-authored papers 1
Arun H S Kumar
Sher-i-Kashmir Institute of Medical Sciences
Co-authored papers 1
Janet Finer-Moore
University of California San Francisco
Co-authored papers 1
Atul Kumar Johri
Jawaharlal Nehru University
Co-authored papers 1
Daniel E Cohen
Co-authored papers 1
Release 1.2