|
| 36778461 | A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in <i>Plasmodium vivax</i> Hypnozoites. | bioRxiv | 2024 |
| 37029122 | Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. | Nat Commun | 2023 |
| 37083395 | Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. | ACS Infect Dis | 2023 |
| 37196868 | Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition. | Bioorg Med Chem Lett | 2023 |
| 34748385 | Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis. | Antimicrob Agents Chemother | 2022 |
| 35703552 | Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy. | Antimicrob Agents Chemother | 2022 |
| 35149760 | Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance. | Commun Biol | 2022 |
| 35134095 | Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis. | PLoS Pathog | 2022 |
| 32277809 | Clofazimine for Treatment of Cryptosporidiosis in Human Immunodeficiency Virus Infected Adults: An Experimental Medicine, Randomized, Double-blind, Placebo-controlled Phase 2a Trial. | Clin Infect Dis | 2021 |
| 33740373 | Repurposing Infectious Disease Hits as Anti-<i>Cryptosporidium</i> Leads. | ACS Infect Dis | 2021 |
| 33648890 | MalDA, Accelerating Malaria Drug Discovery. | Trends Parasitol | 2021 |
| 34523908 | Prioritization of Molecular Targets for Antimalarial Drug Discovery. | ACS Infect Dis | 2021 |
| 34083527 | Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. | Nat Commun | 2021 |
| 34226736 | The Tuberculosis Drug Accelerator at year 10: what have we learned? | Nat Med | 2021 |
| 33466870 | An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease. | Pathogens | 2021 |
| 32892652 | Phenotypic screening techniques for <i>Cryptosporidium</i> drug discovery. | Expert Opin Drug Discov | 2021 |
| 31452169 | High-Content Screening for Cryptosporidium Drug Discovery. | Methods Mol Biol | 2020 |
| 32078764 | Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials. | ACS Infect Dis | 2020 |
| 32998973 | Bicyclic azetidines kill the diarrheal pathogen <i>Cryptosporidium</i> in mice by inhibiting parasite phenylalanyl-tRNA synthetase. | Sci Transl Med | 2020 |
| 32514072 | A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii. | Nat Microbiol | 2020 |
| 32197482 | Antimalarial Peptide and Polyketide Natural Products from the Fijian Marine Cyanobacterium <i>Moorea producens</i>. | Mar Drugs | 2020 |
| 32224991 | High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for <i>Trypanosoma cruzi</i>. | Microorganisms | 2020 |
| 30996125 | Modular, stereocontrolled C<sub>β</sub>-H/C<sub>α</sub>-C activation of alkyl carboxylic acids. | Proc Natl Acad Sci U S A | 2019 |
| 31244158 | Peyssonnosides A-B, Unusual Diterpene Glycosides with a Sterically Encumbered Cyclopropane Motif: Structure Elucidation Using an Integrated Spectroscopic and Computational Workflow. | J Org Chem | 2019 |
| 31323841 | Advances in Antiwolbachial Drug Discovery for Treatment of Parasitic Filarial Worm Infections. | Trop Med Infect Dis | 2019 |
| 31249291 | Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis. | Nat Commun | 2019 |
| 31158574 | Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease. | Int J Parasitol Drugs Drug Resist | 2019 |
| 31074963 | Discovery of Kirromycins with Anti- Wolbachia Activity from Streptomyces sp. CB00686. | ACS Chem Biol | 2019 |
| 31015448 | A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors. | Nat Commun | 2019 |
| 30894487 | Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. | Proc Natl Acad Sci U S A | 2019 |
| 30730745 | Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis. | J Med Chem | 2019 |
| 30908914 | Antibacterial Oligomeric Polyphenols from the Green Alga Cladophora socialis. | J Org Chem | 2019 |
| 29339392 | A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box. | Antimicrob Agents Chemother | 2018 |
| 30155446 | The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis. | Front Cell Infect Microbiol | 2018 |
| 29884783 | Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum. | Nat Commun | 2018 |
| 30523084 | Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. | Science | 2018 |
| 30282735 | The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. | Proc Natl Acad Sci U S A | 2018 |
| 29469575 | Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity. | J Nat Prod | 2018 |
| 29743474 | A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum. | Nat Commun | 2018 |
| 29735709 | Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors. | Proc Natl Acad Sci U S A | 2018 |
| 28899690 | Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis. | Int J Parasitol | 2017 |
| 28158186 | A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis. | PLoS Negl Trop Dis | 2017 |
| 27275010 | High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria. | ACS Infect Dis | 2016 |
| 27291296 | Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor. | Sci Rep | 2016 |
| 25322084 | Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials. | ACS Chem Biol | 2015 |
| 26186534 | Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. | PLoS Pathog | 2015 |
| 25785478 | Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. | J Med Chem | 2015 |
| 24366744 | KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. | Antimicrob Agents Chemother | 2014 |
| 25147620 | Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages. | ACS Med Chem Lett | 2014 |
| 24589256 | Identification of pathogen genomic variants through an integrated pipeline. | BMC Bioinformatics | 2014 |