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Author Details

Wanxia Li Tsai
National Institute of Arthritis
2005
48
29
PMIDPaper TitleJournal TitlePublished Year
37756335Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation.Proc Natl Acad Sci U S A2023
36220328Changes in cardiorespiratory function and fatigue following 12 weeks of exercise training in women with systemic lupus erythematosus: a pilot study.Lupus Sci Med2022
35868845Gain-of-function mutations in <i>ALPK1</i> cause an NF-κB-mediated autoinflammatory disease: functional assessment, clinical phenotyping and disease course of patients with ROSAH syndrome.Ann Rheum Dis2022
35984892PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes.Sci Immunol2022
32843325Janus kinase (JAK) inhibition with baricitinib in refractory juvenile dermatomyositis.Ann Rheum Dis2021
33892719Homozygous variant p. Arg90His in NCF1 is associated with early-onset Interferonopathy: a case report.Pediatr Rheumatol Online J2021
33779074Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS.Arthritis Rheumatol2021
34797715Deubiquitination of proteasome subunits by OTULIN regulates type I IFN production.Sci Adv2021
34099646Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus.Nat Commun2021
342902433-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.Nat Commun2021
32252809Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies.Arthritis Res Ther2020
31726053High throughput pSTAT signaling profiling by fluorescent cell barcoding and computational analysis.J Immunol Methods2020
31827281Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.Nature2020
33108101Somatic Mutations in <i>UBA1</i> and Severe Adult-Onset Autoinflammatory Disease.N Engl J Med2020
30675193SUN2: A potential therapeutic target in cancer.Oncol Lett2019
31015188Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2.Blood2019
30936877Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC.Front Immunol2019
29134648Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients.Clin Pharmacol Ther2018
29993036PSTPIP2 connects DNA methylation to macrophage polarization in CCL4-induced mouse model of hepatic fibrosis.Oncogene2018
30282980Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis.Cell Death Dis2018
29669944Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus.JCI Insight2018
29358286Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors.Ann Rheum Dis2018
29427642Germline gain-of-function myeloid differentiation primary response gene-88 (MYD88) mutation in a child with severe arthritis.J Allergy Clin Immunol2018
27429362Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction.Arthritis Rheumatol2017
28332284EZH2-mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis.J Cell Mol Med2017
28502886HMGA2, a driver of inflammation, is associated with hypermethylation in acute liver injury.Toxicol Appl Pharmacol2017
28118536Cerebrospinal Fluid Cytokines Correlate With Aseptic Meningitis and Blood-Brain Barrier Function in Neonatal-Onset Multisystem Inflammatory Disease: Central Nervous System Biomarkers in Neonatal-Onset Multisystem Inflammatory Disease Correlate With Central Nervous System Inflammation.Arthritis Rheumatol2017
28263189CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.J Clin Invest2017
28544690Brief Report: Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease.Arthritis Rheumatol2017
27818223Hesperitin derivative-11 suppress hepatic stellate cell activation and proliferation by targeting PTEN/AKT pathway.Toxicology2017
27939986Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis.Toxicol Appl Pharmacol2017
26725521Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease.Sci Rep2016
26642243Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease.Nat Genet2016
27731420Whole Chromosome Instability induces senescence and promotes SASP.Sci Rep2016
27396813Role of histone deacetylases(HDACs) in progression and reversal of liver fibrosis.Toxicol Appl Pharmacol2016
27559085Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease.Proc Natl Acad Sci U S A2016
26806094Role of NLRC5 in progression and reversal of hepatic fibrosis.Toxicol Appl Pharmacol2016
26829627Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production.J Clin Invest2016
26802121Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.Proc Natl Acad Sci U S A2016
26934991MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes.Joint Bone Spine2016
26739621PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells.Toxicol Appl Pharmacol2016
26526086Hyperin attenuates inflammation by activating PPAR-γ in mice with acute liver injury (ALI) and LPS-induced RAW264.7 cells.Int Immunopharmacol2015
26371859Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells.Int Immunopharmacol2015
24213371Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib.J Invest Dermatol2014
25029335Activated STING in a vascular and pulmonary syndrome.N Engl J Med2014
24552284Early-onset stroke and vasculopathy associated with mutations in ADA2.N Engl J Med2014
22910563Engineering of an elastic scaffolding polyprotein based on an SH3-binding intrinsically disordered titin PEVK module.Protein Expr Purif2012
16465472Titin PEVK segment: charge-driven elasticity of the open and flexible polyampholyte.J Muscle Res Cell Motil2005
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Collaborators

Massimo Gadina
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 27
Daniel L Kastner
Co-authored papers 14
Sergio D Rosenzweig
National Institute of Allergy and Infectious Diseases
Co-authored papers 6
Elaine F Remmers
Co-authored papers 5
James C Mullikin
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 5
Robert A Colbert
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 4
Peter C Grayson
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 4
Edward W Cowen
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 4
Joshua D Milner
Columbia University
Co-authored papers 3
Laura Santambrogio
Weill Cornell School of Medicine
Co-authored papers 3
Neal S Young
National Heart Lung and Blood Institute Division of Intramural Research
Co-authored papers 3
John J O'Shea
National Institute of Arthritis, National Institutes of Health
Co-authored papers 3
Cristina C Clement
Englander Institute for Precision Medicine
Co-authored papers 2
Yan Huang
National Institute of Allergy and Infectious Diseases
Co-authored papers 2
Settara C Chandrasekharappa
National Institutes of Health
Co-authored papers 2
Martha Quezado
National Cancer Institute (NCI), National Institutes of Health (NIH)
Co-authored papers 2
Yasuko Furumoto
Co-authored papers 2
Marcus Y Chen
and Blood Institute, National Institutes of Health
Co-authored papers 2
Rajesh K Soni
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 2
Michele Nehrebecky
National Human Genome Research Institute, National Institutes of Health (NIH)
Co-authored papers 2
Douglas B Kuhns
Frederick National Laboratory for Cancer Research
Co-authored papers 2
Camilo Toro
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 2
Theo Heller
National Institute of Diabetes and Digestive and Kidney Diseases
Co-authored papers 2
Vineet Gupta
Purdue University
Co-authored papers 1
Xinghao Wang
Co-authored papers 1
Simone Moretti
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati"
Co-authored papers 1
Kari Alitalo
Wihuri Research Institute
Co-authored papers 1
Sarah Gehrke
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Christina Torres Kozycki
National Human Genome Research Institute
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Shilpa Kodati
National Eye Institute, National Institutes of Health
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Release 1.2