Author details

Full Name

Chad J Creighton

Affiliation

ORCID

Career Start Year

1998

Papers

347

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
32341528	Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers.	Nat Genet	2023
37704602	Global impact of somatic structural variation on the cancer proteome.	Nat Commun	2023
37621654	Transcriptomic analyses of ovarian clear-cell carcinoma with concurrent endometriosis.	Front Endocrinol (Lausanne)	2023
37683055	Oncogenic miR-1825 promotes head and neck carcinogenesis via targeting FREM1.		2023
36906706	SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration.		2023
36585450	Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis.	Nat Cancer	2023
37279148	Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer.		2023
37400528	Androgen-regulated stromal complement component 7 (C7) suppresses prostate cancer growth.	Oncogene	2023
37333115	Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load.	Res Sq	2023
37143122	Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer.	J Exp Clin Cancer Res	2023
37141409	Using cancer proteomics data to identify gene candidates for therapeutic targeting.	Oncotarget	2023
36757799	EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.		2023
36945465	Inflammatory memory restrains intestinal stem cell regeneration.		2023
36697831	Author Correction: Genomic basis for RNA alterations in cancer.	Nature	2023
36693152	Gene Expression Profiles in Cancers and Their Therapeutic Implications.		2023
37172086	Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice.	Sci Adv	2023
36731467	Pan-cancer molecular subtypes of metastasis reveal distinct and evolving transcriptional programs.		2023
37292999	Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load.	bioRxiv	2023
32047324	Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers.	Nat Genet	2023
34874914	Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis.	JCI insight	2022
36369237	Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity.	Nat Commun	2022
35654454	The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8<sup>+</sup> cytotoxic T-cell response.	Genes Dev	2022
35948570	Author Correction: Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.	Nat Commun	2022
35562349	Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.	Nat Commun	2022
36001375	Noncanonical Wnt/Ror2 signaling regulates cell-matrix adhesion to prompt directional tumor cell invasion in breast cancer.	Molecular Biology of the Cell	2022
36070687	Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis.	Cell Rep	2022
36261627	STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential.	Oncogene	2022
36495097	Clinical proteomics towards multiomics in cancer.		2022
36481652	Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.	Nat Commun	2022
35045964	Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.	Clin Cancer Res	2022
34987156	Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.	Nat Commun	2022
34864569	Global molecular alterations involving recurrence or progression of pediatric brain tumors.	Neoplasia	2022
35017531	MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade.	Nat Commun	2022
34999736	Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130.	Oncogene	2022
35138907	A functional genomic approach to actionable gene fusions for precision oncology.	Sci Adv	2022
34706306	CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation.	Neoplasia	2021
33586682	MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT.	J Clin Invest	2021
34012099	Correction: YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer.	Oncogene	2021
33743584	SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints.	BMC Bioinformatics	2021
33627787	Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers.	Oncogene	2021
33568653	A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement.	Nat Commun	2021
34155143	Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.	Proceedings of the National Academy of Sciences of the United States of America	2021
34099644	Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis.	Nature Communications	2021
34099494	A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis.	Cancer Research	2021
33882319	Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity.	Cell Reports	2021
33664454	YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer.	Oncogene	2021
33510359	Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumors.	Scientific Reports	2021
34144984	p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi.	Science advances	2021
33875777	A collagen glucosyltransferase drives lung adenocarcinoma progression in mice.	Commun Biol	2021
33921461	Mapping Astrocyte Transcriptional Signatures in Response to Neuroactive Compounds.	International Journal of Molecular Sciences	2021